Effect of NMDA receptor antagonists on behavioral impairment induced by chronic treatment with dexamethasone

Pharmacological Reports

Volumn 57, Issue 1, 2005, Pages 47-54

  Danilczuk, Zofia ^a   Ossowska, Grazyna ^a   Łupina, Tomasz ^a   Cieślik, Katarzyna ^a   Zebrowska Łupina, Iwona ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Dexamethasone; Memantine; Mice; MK 801; Neurotoxicity; NMDA receptor antagonists

Indexed keywords

DEXAMETHASONE; DIZOCILPINE; EXCITATORY AMINO ACID; GLUCOCORTICOID; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; BODY WEIGHT; BRAIN INJURY; BRAIN ISCHEMIA; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; EXTRACELLULAR SPACE; HIPPOCAMPUS; LETHALITY; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; MOTOR COORDINATION; MOTOR DYSFUNCTION; MOUSE; NEUROLOGIC DISEASE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; STRESS; TASK PERFORMANCE; TREATMENT FAILURE; WEIGHT REDUCTION;

EID: 18044378154     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Behl C, Lezoualc'h F, Trapp T, Widmann M, Skutella T, Holsboer F: Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology, 1997, 138, 101-106.
2. Bertorelli R, Adami M, Di Santo E, Ghezzi P: MK-801 and dexamethasone reduce both tumor necrosis factor levels and infarct volume after focal cerebral ischemia in the rat brain. Neurosci Lett, 1998, 246, 41-44.
3. Boissier JR, Tardy J, Diverres JC: Une nouvelle méthode simple pour explorer l'action "tranquillisante": le test de la cheminée. Méd Exp (Basel), 1960, 3, 81-84.
4. Brown ES, Rush AJ, McEwen BS: Hippocampal remodeling and damage by corticosteroids: implications for mood disorders. Neuropsychopharmacology, 1999, 21, 474-484.
5. Chen J, Adachi N, Tsubota S, Nagoro T, Arai T: Dexamethasone augments ischemia-induced extracelluralar accumulation of glutamate in gerbil hippocampus. Eur J Pharmacol, 1998, 347, 67-70.
6. Danilczuk Z, Ossowska G, Wróbel A, Lupina T: Glucocorticoids modulate behavioral effects induced by dopaminergic agonists in rats. Pol J Pharmacol, 2001, 53, 467-473.
7. Danysz W, Parsons CG: The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence. Int J Geriatr Psychiatry, 2003, 18, 23-32.
8. Danysz W, Parsons CG, Komhuher J, Schmidt WJ, Quack G: Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents - preclinical studies. Neurosci Biobehav Rev, 1997, 211, 455-468.
9. De Quervain DJ, Roozendaal B, McGaugh JL: Stress and glucocorticoids impair retrieval of long-term spatial memory. Nature, 1998, 394, 787-790.
10. Endo Y, Nishimura JI, Kimura F: Impairment of maze learning in rats following long-term glucocorticoid treatment. Neurosci Lett, 1996, 203, 199-202.
11. Estupina C, Abarca J, Arancibia S, Belmar J: N-methyl-D-aspartate receptor involvement in dexamethasone- and stress-induced hypothalamic somatostatin release in rats. Neurosci Lett, 1996, 29, 203-206.
12. Farber NB, Wozniak DF, Price MT, Labruyere J, Huss J, Peter HS, Olney JW: Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: potential relevance to schizophrenia? Biol Psychiatry, 1995, 38, 788-796.
13. Feldman S, Weidenfeld J: Hypothalamic mechanisms mediating glutamate effects on the hypothalamo-pituitary-adrenocortical axis. J Neural Transm, 1997, 104, 633-642.
14. 2A receptor binding after chronic corticosterone associated with behavioral indication of depression but not anxiety. Psychoneuroendocrinology, 1997, 22, 477-491.
15. Flavin MP: Influence of dexamethasone on neurotoxicity caused by oxygen and glucose deprivation in vitro. Exp Neurol, 1996, 139, 34-38.
16. Fonnum F, Myhrer T, Paulsen RE, Wangen K, Oksengard AR: Role of glutamate and glutamate receptors in memory function and Alzheimer's disease. Ann NY Acad Sci, 1995, 757, 475-486.
17. Fuchs E, Flügge G: Stress, glucoeorticoids and structural plasticity of the hippocampus. Neurosci Biobehav Rev, 1998, 23, 295-300.
18. Griffiths MR, Cooper AJ, Barber DJ, Mitchell IJ: Pharmacological mechanisms mediating phencyclidine-induced apoptosis of striatopallidal neurons: the roles of glutamate, dopamine, acetylcholine and cortocosteroids. Brain Res, 2000, 855, 1-10.
19. Haynes LE, Griffiths MR, Hyde RE, Barber DJ, Mitchell IJ: Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders. Neuroscience, 2001, 104, 57-69.
20. Hirsch SR, Das I, Garey LJ, de Belleroche J: A pivotal role for glutamate in the pathogenesis of schizophrenia, and its cognitive dysfunction. Pharmacol Biochem Behav, 1997, 56, 797-802.
21. Ikonomidou Ch, Bosch F, Miksa M, Bittigau P, Vöckler J, Dikranian K, Tenkova TI et al.: Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science, 1999, 283, 70-74.
22. Ikonomidou CH, Stefovska V, Turski L: Neuronal death enhanced by N-methyl-D-aspartate antagonists. Proc Natl Acad Sci USA, 2000, 97, 12885-12890.
23. Ismail K, Wessely S: Psychiatric complications of corticosteroid therapy. Br J Hosp Med, 1995, 53, 495-499.
24. Keenan PA, Jacobson MW, Soleymani RM, Mayes MD, Stress ME, Yaldoo DT: The effect on memory of chronic prednisone treatment in patients with systemic disease. Neurology, 1996, 47, 1396-1402
25. Kiraly SJ, Ancill R J, Dimitrova G: The relationship of endogenous cortisol to psychiatric disorder: a review. Can J Psychiatry, 1997, 42, 415-420.
26. Kormhuber J, Weller M: Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy. Biol Psychiatry, 1997, 41, 135-144.
27. Mitchell IJ, Cooper AJ, Griffiths MR, Barber DJ: Phencyclidine and corticosteroids induce apoptosis of a subpopulation of striatal neurons: a neuronal substrate for psychosis? Neuroscience, 1998, 84, 489-501.
28. Morita K, Ishimura K, Tsuruo Y, Wong DL: Dexamethasone enhances serum deprivation-induced necrotic death of rat C6 glioma cells through activation of glucocorticoid receptors. Brain Res, 1999, 816, 309-316.
29. Muir KW, Lees KR: Clinical experience with excitatory amino acid antagonist drugs. Stroke, 1995, 26, 503-513.
30. Newcomer JW, Selke G. Melson AK, Hershey T, Craft S, Richards K, Alderson A: Decreased memory performance in healthy humans induced by stress-level cortisol treatment. Arch Gen Psychiatry, 1999, 556, 527-533.
31. Olney JW, Farber NB: NMDA antagonists as neurotherapeutic drugs, psychotogens, neurotoxins, and research tools for studying schizophrenia. Neuropsychopharmacology, 1995, 13, 335-345.
32. Olney J, Farber NB: Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry, 1995, 52, 998-1007.
33. Parsons CG, Danysz W, Quack G: Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist - a review of preclinical data. Neuropharmacology, 1999, 38, 735-767.
34. Rao VLR, Dogan A, Todd KG, Bowen KK, Dempsey RJ: Neuroprotection by memantine, a non-competitive NMDA receptor antagonist after traumatic brain injury in rats. Brain Res, 2001, 911, 96-100.
35. Seckl JR, Olsson T: Glucocorticoid hypersecretion and the age-impaired hippocampus: cause or effect? J Endocrinol, 1995, 145, 201-211.
36. Sekita-Krzak J, Zebrowska-Lupina I, Czerny K, Stepniewska M, Wróbel A: Neuroprotective effect of ACTH(4-9) in degeneration of hippocampal nerve cells caused by dexamethasone: morpological, immunocytochemical and ultrastructural studies. Acta Neurobiol Exp, 2003, 63, 1-8.
37. Sekita-Krzak J, Zebrowska-Łupina I, Wróbel A, Koziej J: Neurotoxic effects of glucocorticosteroids: morphological examinations of hippocampal cells after experimental administration of dexamethasone. Ann Univ M. Curie-Sklodowska, 1999, 54, 167-172.
38. Tomitaka S, Hashimoto K, Narita N, Minabe Y, Tamura A: Memantine induces heat shock protein HSP70 in the posterior cingulated cortex, retrosplenial cortex and dendate gyrus of rat brain. Brain Res, 1996, 740, 1-5.
39. Venault P, Chapouthier G, de Carvalho LP, Simiand J, Morre M, Dodd RH, Rossier J: Benzodiazepines impair and betacarbolines enhance performance in learning and memory tasks. Nature, 1986, 321, 864-866.
40. Watanabe Y, Gould E, McEwen B: Stress-induced atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res, 1992, 588, 341-345.
41. Wolkowitz OM, Reus VI, Canick J, Levin B, Lupien S: Glucocorticoid medication, memory and steroid psychosis in medical illness. Ann NY Acad Sci, 1997, 823, 81-96.
42. Young AH, Sahakian BJ, Robbins TW, Cowe PJ: The effects of chronic administration of hydrocortisone on cognitive function in normal volunteers. Psychopharmacology, 1999, 145, 260-266.
43. Zajaczkowski W, Hetman M, Nikolaev E, Quack G, Danysz W, Kaczmarek L: Behavioural evaluation of long-term neurotoxic effects of NMDA receptor antagonists. Neurotox Res, 2000, 1, 299-310.