메뉴 건너뛰기




Volumn 25, Issue 7, 2002, Pages 747-752

Age-related macular degeneration: A review of anti-angiogenic treatments;Traitements anti-angiogéniques au cours de la dégénérescence maculaire liée à l'âge

Author keywords

Age related macular degeneration; Anti angiogenic treatment; Choroidal neovascular membrane; Pharmacological therapy

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; APTAMER; CORTICOSTEROID; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; INTEGRIN; INTEGRIN INHIBITOR; LIPOSOME; MATRIX METALLOPROTEINASE INHIBITOR; THALIDOMIDE; TRIAMCINOLONE; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 17944396283     PISSN: 01815512     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (42)
  • 2
    • 0028123090 scopus 로고
    • Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy
    • Adamis AP, Miller JW, Bernal MT et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol, 1994;118:445-50.
    • (1994) Am J Ophthalmol , vol.118 , pp. 445-450
    • Adamis, A.P.1    Miller, J.W.2    Bernal, M.T.3
  • 3
    • 0030875072 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and ocular neovascularization
    • Miller JW. Vascular endothelial growth factor and ocular neovascularization. Am J Pathol, 1997;151:13-23.
    • (1997) Am J Pathol , vol.151 , pp. 13-23
    • Miller, J.W.1
  • 4
    • 0030803649 scopus 로고    scopus 로고
    • Factors controlling ocular angiogenesis
    • Casey R, Li WW. Factors controlling ocular angiogenesis. Am J Ophthalmol, 1997;124:521-9.
    • (1997) Am J Ophthalmol , vol.124 , pp. 521-529
    • Casey, R.1    Li, W.W.2
  • 5
    • 0010712792 scopus 로고    scopus 로고
    • Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity
    • Brooks PC, Silletti S, von Schalscha TL, Friedlander M, Cheresh DA. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell 1998;92:391-400.
    • (1998) Cell , vol.92 , pp. 391-400
    • Brooks, P.C.1    Silletti, S.2    Von Schalscha, T.L.3    Friedlander, M.4    Cheresh, D.A.5
  • 6
    • 0031719049 scopus 로고    scopus 로고
    • Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes
    • Steen B, Sejersen S, Berglin L, Seregard S, Kvanta A. Matrix metalloproteinases and metalloproteinase inhibitors in choroidal neovascular membranes. Invest Ophthalmol Vis Sci, 1998;39:2194-200.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 2194-2200
    • Steen, B.1    Sejersen, S.2    Berglin, L.3    Seregard, S.4    Kvanta, A.5
  • 7
    • 0028670833 scopus 로고
    • Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks PC, Montgomery AM, Rosenfeld M et al. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell, 1994;79:1157-64.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3
  • 8
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science, 1994;264:569-71.
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 9
    • 0030484702 scopus 로고    scopus 로고
    • Role of integrins in angiogenesis
    • Brooks PC. Role of integrins in angiogenesis. Eur J Cancer, 1996;32A:2423-9.
    • (1996) Eur J Cancer , vol.32 A , pp. 2423-2429
    • Brooks, P.C.1
  • 11
    • 0029843947 scopus 로고    scopus 로고
    • Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases
    • Friedlander M, Theesfeld CL, Sugita M et al. Involvement of integrins alpha v beta 3 and alpha v beta 5 in ocular neovascular diseases. Proc Natl Acad Sci U S A, 1996;93:9764-9.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9764-9769
    • Friedlander, M.1    Theesfeld, C.L.2    Sugita, M.3
  • 12
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell, 1992;69:11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 14
    • 0342313474 scopus 로고    scopus 로고
    • Teratogen update: Thalidomide: A review, with a focus on ocular findings and new potential uses
    • Miller MT, Stromland K. Teratogen update: Thalidomide: A review, with a focus on ocular findings and new potential uses. Teratology, 1999;60:306-21.
    • (1999) Teratology , vol.60 , pp. 306-321
    • Miller, M.T.1    Stromland, K.2
  • 16
    • 0031018867 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with nonproliferative diabetic retinopathy
    • Amin RH, Frank RN, Kennedy A, Eliott D, Puklin JE, Abrams GW. Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with nonproliferative diabetic retinopathy. Invest Ophthalmol Vis Sci, 1997;38:36-47.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 36-47
    • Amin, R.H.1    Frank, R.N.2    Kennedy, A.3    Eliott, D.4    Puklin, J.E.5    Abrams, G.W.6
  • 17
    • 0030832082 scopus 로고    scopus 로고
    • Growth factors in age-related macular degeneration: Pathogenic and therapeutic implications
    • Frank RN. Growth factors in age-related macular degeneration: Pathogenic and therapeutic implications. Ophthalmic Res, 1997;29:341-53.
    • (1997) Ophthalmic Res , vol.29 , pp. 341-353
    • Frank, R.N.1
  • 18
    • 0029879849 scopus 로고    scopus 로고
    • Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes
    • Lopez PF, Sippy BD, Lambert HM, Thach AB, Hinton DR. Transdifferentiated retinal pigment epithelial cells are immunoreactive for vascular endothelial growth factor in surgically excised age-related macular degeneration-related choroidal neovascular membranes. Invest Ophthalmol Vis Sci, 1996;37:855-68.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 855-868
    • Lopez, P.F.1    Sippy, B.D.2    Lambert, H.M.3    Thach, A.B.4    Hinton, D.R.5
  • 19
    • 0028037723 scopus 로고
    • Growth factor localization in choroidal neovascular membranes of age-related macular degeneration
    • Amin R, Puklin JE, Frank RN. Growth factor localization in choroidal neovascular membranes of age-related macular degeneration. Invest Ophthalmol Vis Sci, 1994;35:3178-88.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3178-3188
    • Amin, R.1    Puklin, J.E.2    Frank, R.N.3
  • 20
    • 0028230461 scopus 로고
    • Basic fibroblast growth factor experimentally induced choroidal angiogenesis in the minipig
    • Soubrane G, Cohen SY, Delayre T et al. Basic fibroblast growth factor experimentally induced choroidal angiogenesis in the minipig. Curr Eye Res, 1994;13:183-95.
    • (1994) Curr Eye Res , vol.13 , pp. 183-195
    • Soubrane, G.1    Cohen, S.Y.2    Delayre, T.3
  • 22
    • 0031468395 scopus 로고    scopus 로고
    • Systemic hyperoxia decreases vascular endothelial growth factor gene expression in ischemic primate retina
    • Pournaras CJ, Miller JW, Gragoudas ES et al. Systemic hyperoxia decreases vascular endothelial growth factor gene expression in ischemic primate retina. Arch Ophthalmol, 1997;115:1553-8.
    • (1997) Arch Ophthalmol , vol.115 , pp. 1553-1558
    • Pournaras, C.J.1    Miller, J.W.2    Gragoudas, E.S.3
  • 23
    • 0028786651 scopus 로고
    • Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins
    • Aiello LP, Pierce EA, Foley ED et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci U S A, 1995;92:10457-61.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 10457-10461
    • Aiello, L.P.1    Pierce, E.A.2    Foley, E.D.3
  • 24
    • 0029925079 scopus 로고    scopus 로고
    • Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization
    • Hammes HP, Brownlee M, Jonczyk A, Sutter A, Preissner KT. Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization. Nat Med, 1996;2:529-33.
    • (1996) Nat Med , vol.2 , pp. 529-533
    • Hammes, H.P.1    Brownlee, M.2    Jonczyk, A.3    Sutter, A.4    Preissner, K.T.5
  • 26
    • 0034466813 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of an antivascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
    • Drolet DW, Nelson J, Tucker CE et al. Pharmacokinetics and safety of an antivascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys. Pharm Res, 2000;17:1503-10.
    • (2000) Pharm Res , vol.17 , pp. 1503-1510
    • Drolet, D.W.1    Nelson, J.2    Tucker, C.E.3
  • 27
    • 0032955659 scopus 로고    scopus 로고
    • Retinal neovascularization is suppressed with a matrix metalloproteinase inhibitor
    • Das A, McLamore A, Song W, McGuire PG. Retinal neovascularization is suppressed with a matrix metalloproteinase inhibitor. Arch Ophthalmol, 1999;117:498-503.
    • (1999) Arch Ophthalmol , vol.117 , pp. 498-503
    • Das, A.1    McLamore, A.2    Song, W.3    McGuire, P.G.4
  • 28
    • 0033944912 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide in exudative age-related macular degeneration
    • Danis RP, Ciulla TA, Pratt LM, Anliker W. Intravitreal triamcinolone acetonide in exudative age-related macular degeneration. Retina, 2000;20:244-50.
    • (2000) Retina , vol.20 , pp. 244-250
    • Danis, R.P.1    Ciulla, T.A.2    Pratt, L.M.3    Anliker, W.4
  • 29
    • 0030955337 scopus 로고    scopus 로고
    • Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization
    • BenEzra D, Griffin BW, Maftzir G, Sharif NA, Clark AF. Topical formulations of novel angiostatic steroids inhibit rabbit corneal neovascularization. Invest Ophthalmol Vis Sci, 1997;38:1954-62.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 1954-1962
    • BenEzra, D.1    Griffin, B.W.2    Maftzir, G.3    Sharif, N.A.4    Clark, A.F.5
  • 30
    • 0032882397 scopus 로고    scopus 로고
    • Angiostatic activity of steroids in the chick embryo CAM and rabbit cornea models of neovascularization
    • McNatt LG, Weimer L, Yanni J, Clark AF. Angiostatic activity of steroids in the chick embryo CAM and rabbit cornea models of neovascularization. J Ocul Pharmacol Ther, 1999;15:413-23.
    • (1999) J Ocul Pharmacol Ther , vol.15 , pp. 413-423
    • McNatt, L.G.1    Weimer, L.2    Yanni, J.3    Clark, A.F.4
  • 31
    • 6544281475 scopus 로고    scopus 로고
    • Inhibition of intraocular tumor growth by topical application of the angiostatic steroid anécortave acetate
    • Clark AF, Mellon J, Li XY et al. Inhibition of intraocular tumor growth by topical application of the angiostatic steroid anécortave acetate. Invest Ophthalmol Vis Sci, 1999;40:2158-62.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2158-2162
    • Clark, A.F.1    Mellon, J.2    Li, X.Y.3
  • 32
    • 0035161760 scopus 로고    scopus 로고
    • The effect of an angiostatic steroid on neovascularization in a rat model of retinopathy of prematurity
    • Penn JS, Rajaratnam VS, Collier RJ, Clark AF. The effect of an angiostatic steroid on neovascularization in a rat model of retinopathy of prematurity. Invest Ophthalmol Vis Sci, 2001;42:283-90.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 283-290
    • Penn, J.S.1    Rajaratnam, V.S.2    Collier, R.J.3    Clark, A.F.4
  • 33
    • 0029859140 scopus 로고    scopus 로고
    • Antagonists of integrin alpha v beta 3 inhibit retinal neovascularization in a murine model
    • Luna J, Tobe T, Mousa SA, Reilly TM, Campochiaro PA. Antagonists of integrin alpha v beta 3 inhibit retinal neovascularization in a murine model. Lab Invest, 1996;75:563-73.
    • (1996) Lab Invest , vol.75 , pp. 563-573
    • Luna, J.1    Tobe, T.2    Mousa, S.A.3    Reilly, T.M.4    Campochiaro, P.A.5
  • 34
    • 0031453118 scopus 로고    scopus 로고
    • Integrin chatter and vascular function in diabetic retinopathy
    • Preissner KT, Kanse SM, Hammes HP. Integrin chatter and vascular function in diabetic retinopathy. Horm Metab Res, 1997;29:643-5.
    • (1997) Horm Metab Res , vol.29 , pp. 643-645
    • Preissner, K.T.1    Kanse, S.M.2    Hammes, H.P.3
  • 35
    • 15844420283 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
    • Brooks PC, Stromblad S, Sanders LC et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell, 1996;85:683-93.
    • (1996) Cell , vol.85 , pp. 683-693
    • Brooks, P.C.1    Stromblad, S.2    Sanders, L.C.3
  • 36
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly MS, Holmgren L, Shing Y et al. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell, 1994;79:315-28.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3
  • 37
    • 0037931645 scopus 로고    scopus 로고
    • Recombinant kringle 1-3 of plasminogen inhibits rabbit corneal angiogenesis induced by angiogenin
    • Shin SH, Kim JC, Chang SI, Lee H, Chung SI. Recombinant kringle 1-3 of plasminogen inhibits rabbit corneal angiogenesis induced by angiogenin. Cornea, 2000;19:212-7.
    • (2000) Cornea , vol.19 , pp. 212-217
    • Shin, S.H.1    Kim, J.C.2    Chang, S.I.3    Lee, H.4    Chung, S.I.5
  • 38
    • 0033621350 scopus 로고    scopus 로고
    • The inhibitory effects of recombinant plasminogen kringle 1-3 on the neovascularization of rabbit cornea induced by angiogenin, bFGF, and VEGF
    • Kim JH, Kim JC, Shin SH, Chang SI, Lee HS, Chung SI. The inhibitory effects of recombinant plasminogen kringle 1-3 on the neovascularization of rabbit cornea induced by angiogenin, bFGF, and VEGF. Exp Mol Med, 1999;31:203-9.
    • (1999) Exp Mol Med , vol.31 , pp. 203-209
    • Kim, J.H.1    Kim, J.C.2    Shin, S.H.3    Chang, S.I.4    Lee, H.S.5    Chung, S.I.6
  • 39
    • 0033753701 scopus 로고    scopus 로고
    • Photodynamic therapy using Lu-Tex induces apoptosis in vitro, and its effect is potentiated by angiostatin in retinal capillary endothelial cells
    • Renno RZ, Delori FC, Holzer RA, Gragoudas ES, Miller JW. Photodynamic therapy using Lu-Tex induces apoptosis in vitro, and its effect is potentiated by angiostatin in retinal capillary endothelial cells. Invest Ophthalmol Vis Sci, 2000;41:3963-71.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3963-3971
    • Renno, R.Z.1    Delori, F.C.2    Holzer, R.A.3    Gragoudas, E.S.4    Miller, J.W.5
  • 40
    • 0030700775 scopus 로고    scopus 로고
    • Iontophoresis of dexamethasone in the treatment of endotoxin-induced-uveitis in rats
    • Behar-Cohen FF, Parel JM, Pouliquen Y et al. Iontophoresis of dexamethasone in the treatment of endotoxin-induced-uveitis in rats. Exp Eye Res, 1997;65:533-45.
    • (1997) Exp Eye Res , vol.65 , pp. 533-545
    • Behar-Cohen, F.F.1    Parel, J.M.2    Pouliquen, Y.3
  • 41
    • 0034114629 scopus 로고    scopus 로고
    • Transscleral delivery of bioactive protein to the choroid and retina
    • Ambati J, Gragoudas ES, Miller JW et al. Transscleral delivery of bioactive protein to the choroid and retina. Invest Ophthalmol Vis Sci, 2000;41:1186-91.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1186-1191
    • Ambati, J.1    Gragoudas, E.S.2    Miller, J.W.3
  • 42
    • 0034031474 scopus 로고    scopus 로고
    • Diffusion of high molecular weight compounds through sclera
    • Ambati J, Canakis CS, Miller JW et al. Diffusion of high molecular weight compounds through sclera. Invest Ophthalmol Vis Sci, 2000;41:1181-5.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1181-1185
    • Ambati, J.1    Canakis, C.S.2    Miller, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.