Influence of rhinologic usual and unusual drugs on fibroblasts from nasal polyps in cell culture;Verhalten von fibroblasten aus nasenpolypen in zellkultur nach applikation üblicher rhinologika und unüblicher medikamente unterschiedlicher wirkstoffgruppen

Laryngo- Rhino- Otologie

Volumn 82, Issue 6, 2003, Pages 408-415

  Ostwald, Jürgen ^a   Graumuller S ^a   Dommerich, S ^a   Hoff, M ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Cell culture; Cytotoxicity; Drug; Fibroblasts; Nasal polyps; Proliferation

Indexed keywords

BECLOMETASONE; DICLOFENAC; FLUORESCEIN ISOTHIOCYANATE; FLUTICASONE; METHYLPREDNISOLONE; MOMETASONE FUROATE; PENTOXIFYLLINE; PILOCARPINE; PIROXICAM; PREDNISOLONE HEMISUCCINATE; TIMOLOL; VERAPAMIL;

ARTICLE; CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NOSE POLYP; PRIORITY JOURNAL; SURGICAL APPROACH;

ADMINISTRATION, TOPICAL; ADRENERGIC BETA-ANTAGONISTS; ANDROSTADIENES; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIRHEUMATIC AGENTS; BECLOMETHASONE; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; CULTURE MEDIA; DICLOFENAC; FIBROBLASTS; GLUCOCORTICOIDS; HEMATOLOGIC AGENTS; HUMANS; MESALAMINE; METHYLPREDNISOLONE; MUSCARINIC AGONISTS; NASAL POLYPS; PENTOXIFYLLINE; PILOCARPINE; PIROXICAM; PREDNISOLONE; PREGNADIENEDIOLS; TIME FACTORS; TIMOLOL; VERAPAMIL;

EID: 17944391776     PISSN: 09358943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-40541     Document Type: Article

References (36)

1. Kirsch JP, White JA. Nasal polyposis. J La state Med Soc 1990; 142: 11-14
2. Rudack C. Untersuchungen zum Entzündungsgeschehen in Nasenpolypen. Laryngo-Rhino-Otologie 2002; 81: 659-660
3. Rudack C, Hauser U, Stoll W. Einfluss von Zytokinen und Fibroblasten auf die Überlebenszeit eosinophiler Granulozyten bei der Polyposis nasi. Laryngo-Rhino-Otologie 1999; 78: 378-381
4. Bachert C, Lange B. Polyposis Nasi. Allergiemanagment 1999; 4: 27-32
5. Bachert C, Wagenmann M, Rudack C, Hopken K, Hillebrandt M, Wang D, van Cauwenberge P. The role of cytokines in infectious sinusitis and nasal polyposis. Allergy 1998; 53: 2-13
6. Weber A, Schröder UH, May A, von Ilberg C, Frömter E. Chloridleitfähigkeit nasaler Fibroblasten von Polyposis-Patienten mit zystischer Fibrose und Patienten ohne zystische Fibrose. HNO 1997; 45: 695-701
7. Wang D, Levasseur-Acker GM, Jankowski R, Kanny G, Moneret-Vautrin DA, Charron D, Lockhart A, Swierczewski E. HLA class II antigens and T lymphocytes in human nasal epithelial cells. Modulation of the HLA class II gene transcripts by gamma interferon. Clin Exp Allergy 1997; 27: 306-314
8. Nonaka M, Pawankar R, Saji F, Yagi T. Effect of roxithromycin on IL-8 synthesis and proliferation of nasal polyp fibroblasts. Acta Otolaryngol Suppl 1998; 539: 71-75
9. Nakagawa T, Yamane H, Nakai Y, Shigeta T, Takashima T, Takeda Z. Comparative assessment of cell proliferation and accumulation of extracellular matrix in nasal polyps. Acta Otolaryngol Suppl 1998; 538: 205-208
10. Umbach B, Hennebach U. Veränderungen im Bindegewebsmetabolismus von Fibroblasten aus Nasenpolypen. HNO 1994; 42: 344-349
11. Larsen PL, Tos M, Kuijpers W, van der Beek JM. The early stages of polyp formation. Laryngoscope 1992; 102: 670-677
12. Johansen LV, Illum P, Kristensen S, Winther L, Petersen SV, Synnerstad P. The effect of budenoside (Rhinocort) in the treatment of small and medium sized nasal polyps. Clin Otolaryngol 1993; 18: 524-527
13. Rhuno J, Anderson B, Denburg J. A double-blind comparision of intranasal budenoside with placebo for nasal popyposis. J Allergy Clin Immunol 1990; 86: 946-953
14. Williams DE, Nguyen KD, Shapourifar-Tehrani S, Kitada S, Lee DA. Effects of timolol, betaxolol, and levobunolol on human tenon's fibroblasts in tissue culture. Invest Ophthalmol Vis Sci 1992; 33: 2233-2241
15. Cunlife IA, McIntyre CA, Rees RC, Rennie IG. The effect of topical cholinergic medications on human Tenon's capsule fibroblasts in tissue culture. Graefes Arch Clin Exp Ophthalmol 1995; 233: 507-512
16. Lange K, Kleuser B, Gysler A, Bader M, Maia C, Scheidereit C, Korting HC, Schafer-Korting M. Cutaneous inflammation and proliferation in vitro: differential effects and mode of action of topical glucocorticoids. Skin Pharmacol Appl Skin Physiol 2000; 13: 93-103
17. Muhlberg T, Joba W, Spitzweg C, Schworm HD, Heberling HJ, Heufelder AE. Interleukin-1 receptor antagonist ribonucleic acid and protein expression by cultured Graves' and normal orbital fibroblasts is differentially modulated by dexamethasone and irradiation. J Clin Endocrinol Metab 2000; 85: 734-742
18. Hein R, Korting HC, Mehring T. Differential effect of medium potent nonhalogenated double-ester-type and conventional glucocorticoids on proliferation and chemotaxis of fibroblasts in vitro. Skin Pharmacol 1994; 7: 300-306
19. Gormar FE, Bernd A, Holzmann H. The effect of hydrocortisone aceponate on proliferation, total protein synthesis and collagen synthesis in human skin fibroblasts in vitro. Arzneimittelforschung 1990; 40: 192-196
20. Silvestri M, Sabatini F, Scarso L, Cordone A, Dasic G, Rossi GA. Fluticasone propionate downregulates nasal fibroblast functions involved in airway inflammation and remodeling. Int Arch Allergy Immunol 2002; 128: 51-58
21. Li S, Mawal-Dewan M, Cristofalo VJ, Sell C. Enhanced proliferation of human fibroblasts, in the presence of dexamethasone, is accompanied by changes in p21Waf1/Cip1/Sdi1 and the insulin-like growth factor type 1 receptor. J Cell Physiol 1998; 177: 396-401
22. Albrecht M, Janssen M, Konrad L, Renneberg H, Aumuller G. Effects of dexamethasone on proliferation of and fibronectin synthesis by human primary prostatic stromal cells in vitro. Andrologia 2002; 34: 11-21
23. Bruzzese N, Sica G, Iacopino F, Paludetti G, Schiavino D, Nucera E, Scarano E, Patriarca G. Growth inhibition of fibroblasts from nasal polyps and normal skin by lysine acetylsalicylate. Allergy 1998; 53: 431-434
24. Tarpila E, Franzen L, Ghassemifar R, Risto O. The effect of diclofenac (Voltaren) on the contraction of collagen lattices. Scand J Plast Reconstr Surg Hand Surg 1997; 31: 105-107
25. Sun R, Gimbel HV, Liu S, Guo D, Hollenberg MD. Effect of diclofenac sodium and dexamethasone on cultured human Tenon's capsule fibroblasts. Ophthalmic Surg Lasers 1999; 5: 382-388
26. Nguyen KD, Lee DA. In vitro evaluation of antiproliferative potential of topical cyclooxygenase inhibitors in human Tenon's fibroblasts. Exp Eye Res 1993; 57: 97-105
27. Mattey DL, Evans E, Dawes PT. The effects of Tenidap on cytokine induced proliferation of human synovial fibroblasts in vitro. Ann Rheum Dis 1994; 53: 250-255
28. Zeitler H, Ko Y, Glodny B, Totzke G, Appenheimer M, Sachinidis A, Vetter H. Cell-cycle arrest in G0/G1 phase of growth factor-induced endothelial cell proliferation by various calcium channel blockers. Cancer Detect Prev 1997; 21: 332-339
29. Kang Y, Lee DA, Higginbotham EJ. In vitro evaluation of antiproliferative potential of calcium channel blockers in human Tenon's fibroblasts. Exp Eye Res 1997; 64: 913-925
30. Anderson MS, Shankey TV, Lubrano T, Mulhall JP. Inhibition of Peyronie's plaque fibroblast proliferation by biologic agents. Int J Impot Res 2000; 12(Suppl 3): 25-31
31. Chidiac P, Hebert TE, Valiquette M, Dennis M, Bouvier M. Inverse agonist activity of beta-adrenergic antagonists. Mol Pharmacol 1994; 45: 490-499
32. Hussain SS, Al-Dakan AA, Aboul-Enein HY, Hannan MA. DNA strand breaks and mutations caused by penbutolol, a beta blocker. Mutat Res 1988; 204: 675-682
33. Wu KY, Hong SJ, Wang HZ. Effects of pilocarpine and other antiglaucoma drugs on cultured human Tenon's fibroblast cells. J Ocul Pharmacol Ther 1997; 13: 13-21.
34. Strutz F, Heeg M, Kochsiek T, Siemers G, Zeisberg M, Muller GA. Effects of pentoxifylline, pentifylline and gamma-interferon on proliferation, differentiation, and matrix synthesis of human renal fibroblasts. Nephrol Dial Transplant 2000; 15: 1535-1546
35. Desmouliere A, Xu G, Costa AM, Yousef IM, Gabbiani G, Tuchweber B. Effect of pentoxifylline on early proliferation and phenotypic modulation of fibrogenic cells in two rat models of liver fibrosis and on cultured hepatic stellate cells. J Hepatol 1999; 30: 621-631
36. Hewitson TD, Martic M, Kelynack KJ, Pedagogos E, Becket GJ. Pentoxifylline reduces in vitro renal myofibroblast proliferation and collagen secretion. Am J Nephrol 2000; 20: 82-88