Effect of pentoxifylline on antioxidant status of healthy and endotoxemic New Zealand white rabbits

Acta Veterinaria Brno

Volumn 74, Issue 1, 2005, Pages 17-21

  Keskin, E ^a   Oztekin, E ^a   Coli, R ^b   Sivrikaya, A ^a   Uney, K ^a   Yazar, E ^a  

^a SELCUK UNIVERSITY   (Turkey)

^b NONE

Author keywords

Antioxidant status; Lipopolysaccharide; Pentoxifylline; Rabbits

Indexed keywords

GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PENTOXIFYLLINE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; ENZYME ACTIVITY; ESCHERICHIA COLI; HEART; KIDNEY; LIVER; MALE; NONHUMAN; RABBIT;

EID: 17844408660     PISSN: 00017213     EISSN: None     Source Type: Journal    
DOI: 10.2754/avb200574010017     Document Type: Article

References (31)

1. ABD EL-GAWAD, HM, KHALIFA, AE 2001: Quercetin, coenzyme Q10, and L-canavanine as protective agents lipid peroxidation and nitric oxide generation in endotoxin-induced shock in rat brain. Pharmacol Res 43: 257-263
2. ALTAVILLA, D, SQUADRITO, G, MINUTOLI, L, DEODATO, B, BOVA, A, SARDELLA, A, SEMINARA, P, PASSANITI, M, URNA, G, VENUTI, SF, CAPUTI, AP, SQUADRITO, F 2002: Inhibition of nuclear factor-kB activation by IRFI 042, protects against endotoxin-induced shock. Cardiovasc Res 54: 684-693
3. ARIAS-DIAZ, J, VARA, E, TORRES-MELERO, J, GARCIA, C, HERNANDEZ, J, BALIBREA, JL 1997: Local production of oxygen free radicals and nitric oxide in rat diaphragm during sepsis: Effects of pentoxifylline and somatostatin. Eur J Surg 163: 619-625
4. BEKERECIOGLU, M, KUTLUHAN, A, DEMIRTAS, I, KARAAYVAZ, M 1998: Prevention of adriamycin-induced skin necrosis with various free radical scavengers. J Surg Res 75: 61-65
5. BEN-SHAUL, V, LOMNITSKI, L, NYSKA, A, ZUROVSKY, Y, BERGMAN, M, GROSSMAN, S 2001: The effect of natural antioxidants, NAO and apomycin, on oxidative stress in the rat hear following LPS challenge. Toxicol Lett 123: 1-10
6. CADENAS, S, CADENAS, AM 2002: Fighting the stranger-antioxidant protection against endotoxin toxicity. Toxicology 180: 45-63
7. CATALA, M, PORTOLES, MT 2002: Action of E. coli endotoxin, IL-1β and TNF-α on antioxidant status of cultured hepatocytes. Mol Cell Biochem 231: 75-82
8. CHAN, KM, DECKER, EA 1994: Endogenous skeletal muscle antioxidants. Crit Rev Food Sci Nutr 34: 403-426
9. CNUBBEN, NHP, RIETJENS, IMCM, WORTELBOER, H, VAN-ZANDEN, J, VAN BLADEREN, PJ 2001: The interplay of glutathione related processes in antioxidant defense. Environ Toxicol Pharmacol 10: 141-152
10. DEMIR, S, INAL-ERDEN, M 1998: Pentoxifylline and N-acetylcystein in hepatic ischemia/reperfusion injury. Clin Chim Acta 275: 127-135
11. DRINGEN, R 2000: Metabolism and functions of glutathione in brain. Prog Neurobiol 62: 649-641
12. ELLMANN, GL 1959: Tissue sulfhydryl groups. Arch Biochem Biophys 82: 70-77
13. HANNA, NF 2003: Sepsis and septic shock. Top Emerg Med 25: 158-165
14. HARDAWAY, RM 2000: A review of septic shock. Am Surg 66: 22-29
15. HORVATH, B, MARTON, R, HALMOSI, R, ALEXY, T, SZAPARY, L, VEKASI, J, BIRO, Z, HABON, T, KESMARKY, G, TOTH, K 2002: In vitro antioxidant properties of pentoxifylline, piracetam, and vinpocetine. Clin Neuropharmacol 25: 37-42
16. JOE, B, LOKESH, BR 1997: Studies on the inactivation of superoxide dismutase activity by nitric oxide from rat peritoneal macrophages. Mol Cell Biochem 168: 87-93
17. KAYA, S 1997: Circulatory shock and treatment. In: KAYA, S, PIRINCCI, I, BILGILI, A (Eds).: Veterinary Applied Pharmacology. Volume 2, Medisan, Ankara, pp. 147-152
18. KHEIR-ELDIN, AA, MOTAWI, TK, GAD, MZ, ABD-ELGAWAD, HM 2001: Protective effect of vitamin E, β-carotene and n-acetylcysteine from the brain oxidative stress induced in rats by lipopolysaccharide. Int J Biochem Cell Biol 33: 475-482
19. KRYSZTOPIK, RJ, MATHESON, PJ, SPAIN, DA, GARRISON, RN, WILSON, MA 2000: Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism. J Surg Res 93: 75-81
20. MACDONALD, J, GALLEY, HF, WEBSTER, NR 2003: Oxidative stress and gene expression in sepsis. Br J Anaest 90: 221-232
21. MIHARA, M, UCHIYAMA, M 1978: Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86: 271-278
22. NORDBERG, J, ARNER, ESJ 2001: Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 31: 1287-1312
23. PEREZ-CAMPO, R, LOPEZ-TORRES, M, ROJAS, C, CADENAS, S, BARJA, G 1993: A comparative study of free radicals in vertebrates-I. Antioxidant enzymes. Comp Biochem Physiol 105: 749-755
24. PFALLER, W, GSTRAUNTHALER, G, WILLINGER, CC 1990: Morphology of renal tubular damage from nephrotoxins. Toxicol Lett 53: 39-43
25. PORTOLES, MT, CATALA, M, ANTON, A, PAGANI, R 1996: Hepatic response to the oxidative stress induced by E. coli endotoxin: Glutathione as an index of the acute phase during the endotoxic shock. Mol Cell Biochem 159: 115-121
26. SALVEMINI, D, CUZZOCREA, S 2002: Oxidative stress in septic shock and disseminated intravascular coagulation. Free Radic Biol Med 33: 1173-1185
27. SUZZOCREA, S, RILEY, DP, CAPUTI, AP, SALVEMINI, D 2001: Antioxidant therapy: A new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol Rev 53: 135-159
28. TOYOKUNI, S 1999: Reactive oxygen species induced molecular damage and its application in pathology. Pathol Int 49: 91-102
29. WU, CC, LIAO, MH, CHEN, SJ, YEN, MH 1999: Pentoxifylline improves circulatory failure and survival in murine models of endotoxemia. Eur J Pharmacol 373: 41-49
30. VALENZUELA, A 1991: The biological significance of malondialdehyde determination in the assessment of tissue oxidative stress. Life Sci 48: 301-309
31. VINCENT, JL 1997: New therapies in sepsis. Chest 112: 330-338