Local production of oxygen free radicals and nitric oxide in rat diaphragm during sepsis: Effects of pentoxifylline and somatostatin

European Journal of Surgery

Volumn 163, Issue 8, 1997, Pages 619-625

  Arias Diaz J ^a   Vara, E ^b   Torres Melero, J ^a   Garcia C ^b   Hernandez J ^a   Balibrea, J L ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Conjugated dienes; Lipopolysaccharide; Malondialdehyde; Myeloperoxidase; Oxygen free radicals; Phospholipase A2

Indexed keywords

MALONALDEHYDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN RADICAL; PENTOXIFYLLINE; PHOSPHOLIPASE A2; SOMATOSTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAPHRAGM; EXPERIMENTAL INFECTION; INTRAPERITONEAL DRUG ADMINISTRATION; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS; TISSUE LEVEL;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL MARKERS; CONFIDENCE INTERVALS; DIAPHRAGM; DISEASE MODELS, ANIMAL; LIPOPOLYSACCHARIDES; MALE; MALONDIALDEHYDE; NITRIC OXIDE; PENTOXIFYLLINE; PEROXIDASE; RANDOM ALLOCATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REFERENCE VALUES; SEPSIS; SOMATOSTATIN;

EID: 0030876645     PISSN: 11024151     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Anzueto A, Supinski GS, Levine N, Jenkinson SG. Mechanisms of disease: are oxygen-derived free radicals involved in diaphragmatic dysfunction? Am J Respir Care Med 1994; 149: 1048-1052.
2. Balibrea JL, Arias-Díaz J, García C, Vara E. Effect of pentoxifylline and somatostatin on tumour necrosis factor production by human pulmonary macrophages. Circ Shock 1994; 43: 51-56.
3. Bermudez LE, Wu M, Young LS. Effect of stress-related hormones on macrophage receptors and response to tumor necrosis factor. Lymphokine Res 1990; 9: 137-145.
4. Bessler H, Gilgal R, Djaldetti M, Zahavi I. Effect of pentoxifylline on the phagocytic activity, cAMP levels and superoxide anion production by monocytes and polymorphonuclear cells. J Leukocyte Biol 1986; 40: 747-754.
5. Bissonnette EY, Hogaboam CM, Wallace JL, Befus AD. Potentiation of tumour necrosis factor-α-mediated cytotoxicity of mast cells by their production of nitric oxide. J Immunol 1991; 147: 3060-3065.
6. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal Biochem 1976; 72: 248-254.
7. Bradley PP, Priebat DA, Christensen RD, Rothestein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 1982; 78: 206-209.
8. Brigham KL, Meyrick B, Bernard GR, et al. Free radicals and arachidonic acid metabolites in endotoxin-induced pulmonary endothelial injury. In: Taylor AE, Matalon S, Ward P, eds. Physiology of oxygen radicals. Bethesda: American Physiological Society, 1986: 199-220.
9. Bromberg Y, Pick E. Unsaturated fatty acids as second messengers of superoxide generation by macrophage. Cell Immunol 1983; 79: 240-252.
10. Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 941-948.
11. Bulkley GB. Endothelial xanthine oxidase: a radical transducer of inflammatory signals for reticuloendothelial activation. Br J Surg 1993; 80: 684-686.
12. Busse R, Mulsch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett 1990; 275: 87-90.
13. Coccia MT, Waxman K, Soliman MH, Tominaga G, Pinderski L. Pentoxifylline improves survival following hemorrhagic shock. Crit Care Med 1989; 17: 36-41.
14. 2 for activation of the assembled NADPH oxidase in human neutrophils. Biochem J 1994; 297: 217-223.
15. 2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein kinase. Proc Natl Acad Sci USA 1994; 91: 3142-3146.
16. Fletcher MA, McKenna TM, Owens EH, Nadkarni VM. Effects of in vivo pentoxifylline treatment on survival and ex vivo vascular contractility in a rat lipopolysaccharide shock model. Circ Shock 1992; 36: 74-80.
17. Hausladen A, Fridovich I. Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not. J Biol Chem 1994; 47: 29405-29408.
18. Horton JW, White DJ. Free radical scavengers prevent intestinal ischemia-reperfusion-mediated cardiac dysfunction (abstract). Physiologist 1991; 34: 227.
19. Hussain SN, Simkus G, Roussos C. Respiratory muscle fatigue: a cause of ventilatory failure in septic shock. J Appl Physiol 1985; 58: 2033-2040.
20. Ishizaka A, Wu ZH, Stephens KE, et al. Attenuation of acute lung injury in septic guinea pigs by pentoxifylline. Am Rev Respir Dis 1988; 138: 376-384.
21. Jorens PG, Van Overveld FJ, Vermeire PA, Bull H, Herman AG. Synergism between interleukin-1β and the nitric oxide synthase inducer interferon-τ in rat lung fibroblasts. Eur J Pharmacol 1992; 224: 7-12.
22. 2 inhibition decouples lung injury from gut ischemia-reperfusion. Surgery 1992; 112: 173-180.
23. Littner MR, Lott FD. Increase in filtration coefficient from actions of melittin on neutrophils in isolated rabbit lungs. Am J Respir Crit Care Med 1994; 149: 867-872.
24. Mandell GL. ARDS, neutrophils and pentoxifylline. Am Rev Respir Dis 1988; 138: 1103-1105.
25. Mansbach II CM. Phospholipases: old enzymes with new meaning. Gastroenterology 1990; 98: 1369-1382.
26. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide physiology, pathology and pharmacology. Pharmacol Rev 1991; 43: 109-142.
27. Park KGM, Hayes PD, Garlick PJ, Sewell H, Eremin O. Stimulation of lymphocyte natural cytotoxicity by L-arginine. Lancet 1991; 337: 645-646.
28. Payan DG, McGillis JP, Goetzl EJ. Neuroimmunology. Adv Immunol 1986; 39: 299-323.
29. Radomski MW, Palmer RMJ, Moncada S. An L-arginine, nitric oxide pathway present in human platelets regulates aggregation. Proc Natl Acad Sci USA 1990; 87: 5193-5197.
30. Recknagel RO, Glende Jr EA. Spectrophotometric detection of lipid conjugated dienes. Methods Enzymol 1984: 331-335.
31. Reid MB, Stokic DS, Koch SM, Khawli FA, Leis AA. N-acetylcysteine inhibits muscle fatigue in humans. J Clin Invest 1994; 94: 2468-2474.
32. Rossignol L, Plantavid M, Chap H, Douste-Blazy L. Effects of two methylxanthines, pentoxifylline and propentofylline, on arachidonic acid metabolism in platelets stimulated by thrombin. Biochem Pharmacol 1988; 37: 3229-3236.
33. Salvemini D, De Nucci G, Gryglewski RJ, Vaner JR. Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. Proc Natl Acad Sci USA 1989; 86: 6328-6332.
34. Stanisz AM, Befus D, Bienenstock J. Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferation by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen. J Immunol 1986; 136: 152-156.
35. Supinski GS, Nethery D, Dimarco A. Effect of free radical scavengers on endotoxin-induced respiratory muscle dysfunction. Am Rev Respir Dis 1993; 148: 1318-1324.
36. Tepperman BL, Vozzolo BL, Soyer BD. Effect of neutropenia on gastric mucosal nitric oxide synthesis in the rat. Dig Dis Sci 1993; 38: 2056-2061.
37. Usadel KH, Schwedes U, Wdowinski JM. Pharmacological effects of somatostatin in acute organ lesions. Inn Med 1982; 9: 204-209.
38. 2 enzyme activity and immunoreactivity in a prospective analysis of patients with septic shock. Life Sci 1992; 50: 807-811.