Cooperative induction of rat mammary cancer by radiation and 1-methyl-1-nitrosourea via the oncogenic pathways involving c-Myc activation and H-ras mutation

International Journal of Cancer

Volumn 115, Issue 2, 2005, Pages 187-193

  Imaoka, Tatsuhiko ^a   Nishimura, Mayumi ^a   Teramoto, Ayako ^a   Nishimura, Yukiko ^a   Ootawara, Masami ^a   Osada, Harumi ^a   Kakinuma, Shizuko ^a   Maekawa, Akihiko ^b   Shimada, Yoshiya ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b SASAKI INSTITUTE   (Japan)

Author keywords

1 methyl 1 nitrosourea; Carcinogenesis; Combined exposure; H ras; Ionizing radiation; Mammary cancer; Mutation

Indexed keywords

CARCINOGEN; COMPLEMENTARY DNA; METHYLNITROSOUREA; RNA;

ADENOCARCINOMA; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER INCIDENCE; CONTROLLED STUDY; FEMALE; FIBROADENOMA; GAMMA IRRADIATION; GENE MUTATION; IMMUNOHISTOCHEMISTRY; IONIZING RADIATION; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; ONCOGENE H RAS; PRIORITY JOURNAL; RADIATION EXPOSURE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADENOCARCINOMA; ALKYLATING AGENTS; ANIMALS; COCARCINOGENESIS; FEMALE; FIBROADENOMA; GAMMA RAYS; GENES, RAS; HUMANS; INCIDENCE; MAMMARY NEOPLASMS, EXPERIMENTAL; METHYLNITROSOUREA; MUTATION; PROTO-ONCOGENE PROTEINS C-MYC; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; SURVIVAL RATE;

EID: 17844401263     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.20904     Document Type: Article

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