Self-organized density patterns of molecular motors in arrays of cytoskeletal filaments

Biophysical Journal

Volumn 88, Issue 5, 2005, Pages 3118-3132

  Klumpp, Stefan ^a   Nieuwenhuizen, Theo M ^a,b   Lipowsky, Reinhard ^a  

^a MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETON PROTEIN; MOLECULAR MOTOR;

ARTICLE; BINDING SITE; CYTOSKELETON; MATHEMATICAL ANALYSIS; MONTE CARLO METHOD; PROTEIN BINDING; SIMULATION; THEORETICAL MODEL;

EID: 17844392871     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.104.056127     Document Type: Article

References (52)

1. Abramowitz, M., and I. Stegun, editors. 1984. Pocketbook of Mathematical Functions. Harri Deutsch, Thun and Frankfurt/Main.
2. Ajdari, A. 1995. Transport by active filaments. Europhys. Lett. 31:69-74.
3. Alberts, B., A. Johnson, J. Lewis, M. Raff, K. Roberts, and P. Walter. 2002 Molecular Biology of the Cell, 4th Ed. Garland, New York and London.
4. Block, S. M., L. S. B. Goldstein, and B. J. Schnapp. 1990. Bead movement by single kinesin molecules studied with optical tweezers. Nature. 348: 348-352.
5. Böhm, K. J., R. Stracke, and E. Unger. 2000. Speeding up kinesin-driven microtubule gliding in vitro by variation of cofactor composition and physicochemical parameters. Cell Biol. Int. 24:335-341.
6. Brinkmann, M., and R. Lipowsky. 2002. Wetting morphologies on substrates with striped surface domains. J. Appl. Phys. 92:4296-4306.
7. Clemmens, J., H. Hess, J. Howard, and V. Vogel. 2003. Analysis of microtubule guidance in open microfabricated channels coated with the motor protein kinesin. Langmuir. 19:1738-1744.
8. Coy, D. L., W. O. Hancock, M. Wagenbach, and J. Howard. 1999. Kinesin's tail domain is an inhibitory regulator of the motor domain. Nat. Cell Biol. 1:288-292.
9. Dahlström, A. B., K. K. Pfister, and S. T. Brady. 1991. The axonal transport motor kinesin is bound to anterogradely transported organelles: quantitative cytofluorimetric studies of fast axonal transport in the rat. Acta Physiol. Scand. 141:469-476.
10. Gau, H., S. Herminghaus, P. Lenz, and R. Lipowsky. 1999. Liquid morphologies on structured surfaces: from microchannels to microchips. Science. 283:46-49.
11. Goldstein, L. S. B., and Z. Yang. 2000. Microfubule-based transport systems in neurons: the roles of kinesins and dyneins. Annu. Rev. Neurosci. 23:39-71.
12. Harrison, B. C., S. P. Marchese-Ragona, S. P. Gilbert, N. Cheng, A. C. Steven, and K. A. Johnson. 1993. Decoration of the microtubule surface by one kinesin head per tubulin heterodimer. Nature. 362:73-75.
13. Hirokawa, N., R. Sato-Yoshitake, T. Yoshida, and T. Kawashima. 1990. Brain dynein (MAP1C) localizes on both anterogradely and retrogradely transported membranous organelles in vivo. J. Cell Biol. 111:1027-1037.
14. Hirokawa, N., R. Sato-Yoshitake, N. Kobayashi, K. K. Pfister, G. S. Bloom, and S. T. Brady. 1991. Kinesin associates with anterogradely transported membranous organelles in vivo. J. Cell Biol. 114:295-302.
15. Holy, T. E., M. Dogterom, B. Yurke, and S. Leibler. 1997. Assembly and positioning of microtubule asters in microfabricated chambers. Proc. Natl. Acad. Sci. USA. 94:6228-6231.
16. Howard, J. 2001. Mechanics of Motor Proteins and the Cytoskeleton. Sinauer Associates, Sunderland, MA.
17. Howard, J., A. J. Hudspeth, and R. D. Vale. 1989. Movement of microtubules by single kinesin molecules. Nature. 342:154-158.
18. Hurd, D. D., and W. M. Saxton. 1996. Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila. Genetics. 144:1075-1085.
19. Hyman, A. A., and E. Karsenti. 1996. Morphogenetic properties of microtubules and mitotic spindle assembly. Cell. 84:401-410.
20. Katz, S., J. L. Lebowitz, and H. Spohn. 1983. Phase transitions in stationary nonequilibrium states of model lattice systems. Phys. Rev. B. 28:1655-1658.
21. King, S. J., and T. A. Schroer. 2000. Dynactin increases the processivity of the cytoplasmic dynein motor. Nat. Cell Biol. 2:20-24.
22. Klumpp, S., and R. Lipowsky. 2003. Traffic of molecular motors through tube-like compartments. J. Stat. Phys. 113:233-268.
23. Klumpp, S., and R. Lipowsky. 2004. Phase transitions in systems with two species of molecular motors. Europhys. Lett. 66:90-96.
24. Konzack, S. 2004. Function of the kinesin motor KipA in organization of the microtubule cytoskeleton and in polar growth of Aspergillus nidulans. PhD thesis. Universität Marburg.
25. Konzack, S., P. E. Rischitor, C. Enke, and R. Fischer. 2005. The role of the kinesin motor KipA in microtubule organization and polarized growth of Aspergillus nidulans. Mol. Biol. Cell. 16:497-506.
26. Krug, J. 1991. Boundary-induced phase transitions in driven diffusive systems. Phys. Rev. Lett. 67:1882-1885.
27. Kruse, K., and F. Jülicher. 2000. Actively contracting bundles of polar filaments. Phys. Rev. Lett. 85:1778-1781.
28. Lipowsky, R., S. Klumpp, and T. M. Nieuwenhuizen. 2001. Random walks of cytoskeletal motors in open and closed compartments. Phys. Rev. Lett. 87:108101.
29. MacDonald, C. T., J. H. Gibbs, and A. C. Pipkin. 1968. Kinetics of biopolymerization on nucleic acid templates. Biopolymers. 6:1-25.
30. Martin, M. A., S. J. Iyadurai, A. Gassman, J. G. Gindhart, Jr., T. S. Hays, and W. M. Saxton. 1999. Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. Mol. Biol. Cell. 10:3717-3728.
31. McGhee, J. D., and P. H. von Hippel. 1974. Theoretical aspects of DNA-protein interactions: cooperative and non-cooperative binding of large ligands to a one-dimensional homogeneous lattice. J. Mol. Biol. 86:469-489.
32. Mehta, A. D., R. S. Rock, M. Rief, J. A. Spudich, M. S. Mooseker, and R. E. Cheney. 1999. Myosin-V is a processive actin-based motor. Nature. 400:590-593.
33. Meyhöfer, E., and J. Howard. 1995. The force generated by a single kinesin molecule against an elastic load. Proc. Natl. Acad. Sci. USA. 92:574-578.
34. Nédélec, F., T. Surrey, A. C. Maggs, and S. Leibler. 1997. Self-organization of microtubules and motors. Nature. 389:305-308.
35. Nédélec, F., T. Surrey, and A. C. Maggs. 2001. Dynamic concentration of motors in microtubule arrays. Phys. Rev. Lett. 86:3192-3195.
36. Nieuwenhuizen, T. M., S. Klumpp, and R. Lipowsky. 2002. Walks of molecular motors in two and three dimensions. Europhys. Lett. 58:468-474.
37. Nieuwenhuizen, T. M., S. Klumpp, and R. Lipowsky. 2004. Random walks of molecular motors arising from diffusional encounters with immobilized filaments. Phys. Rev. E. 69:061911.
38. Okada, Y., and N. Hirokawa. 1999. A processive single-headed motor: kinesin superfamily protein KIF1A. Science. 283:1152-1157.
39. Press, W. H., S. A. Teukolsky, W. T. Vetterling, and B. P. Flannery. 1992. Numerical Recipes in C, 2nd Ed. Cambridge University Press, Cambridge, UK.
40. Schliwa, M., and G. Woehlke. 2003. Molecular motors. Nature. 422:759-765.
41. Schnitzer, M. J., and S. M. Block. 1997. Kinesin hydrolyses one ATP per 8-nm step. Nature. 388:386-390.
42. Seiler, S., J. Kirchner, C. Horn, A. Kallipolitou, G. Woehlke, and M. Schliwa. 2000. Cargo binding and regulatory sites in the tail of fungal conventional kinesin. Nat. Cell Biol. 2:333-338.
43. Song, Y.-H., and E. Mandelkow. 1993. Recombinant kinesin motor domain binds to β-tubulin and decorates microtubules with a B-surface lattice. Proc. Natl. Acad. Sci. USA. 90:1671-1675.
44. Surrey, T., F. Nédélec, S. Leibler, and E. Karsenti. 2001. Physical properties determining self-organization of motors and microtubules. Science. 292:1167-1171.
45. Svoboda, K., C. F. Schmidt, B. J. Schnapp, and S. M. Block. 1993. Direct observation of kinesin stepping by optical trapping interferometry. Nature. 365:721-727.
46. Takiguchi, K. 1991. Heavy meromyosin induces sliding movements between antiparallel actin filaments. J. Biochem. (Tokyo). 109:520-527.
47. Tomishige, M., D. R. Klopfenstein, and R. D. Vale. 2002. Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization. Science. 297:2263-2267.
48. Urrutia, R., M. A. McNiven, J. P. Albanesi, D. B. Murphy, and B. Kachar. 1991. Purified kinesin promotes vesicle motility and induces active sliding between microtubules in vitro. Proc. Natl. Acad. Sci. USA. 88:6701-6705.
49. Vale, R. D., T. Funatsu, D. W. Pierce, L. Romberg, Y. Harada, and T. Yanagida. 1996. Direct observation of single kinesin molecules moving along microtubules. Nature. 380:451-453.
50. Veigel, C., F. Wang, M. L. Bartoo, J. R. Sellers, and J. E. Molloy. 2002. The gated gait of the processive molecular motor, myosin V. Nat. Cell Biol. 4:59-65.
51. Verhey, K. J., D. L. Lizotte, T. Abramson, L. Barenboim, B. J. Schnapp, and T. A. Rapoport. 1998. Light-chain dependent regulation of kinesin's interaction with microtubules. J. Cell Biol. 143:1053-1066.
52. Wang, Z., and M. P. Sheetz. 2000. The C-terminus of tubulin increases cytoplasmic dynein and kinesin processivity. Biophys. J. 78:1955-1964.