Hypoxia-induced radioresistance is independent of hypoxia-inducible factor-1A in vitro

International Journal of Radiation Oncology Biology Physics

Volumn 62, Issue 1, 2005, Pages 207-212

  Arvold, Nils D ^a   Guha, Neela ^a   Wang, Dongfang ^a   Matli, Mary ^a   Deen, Dennis F ^a   Warren, Robert S ^a   Haas Kogan, Daphne A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

HIF 1; Hypoxia; Oxygen enhancement ratio; Radiation resistance

Indexed keywords

BIOASSAY; CELLS; ONCOLOGY; OXYGEN;

CLONOGENIC SURVIVAL ASSAYS; FIBROBLASTS; HYPOXIA-INDUCED RADIORESISTANCE; NORMOXIC CONDITIONS;

RADIOTHERAPY;

HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; FIBROBLAST; HYPOXIA; IN VITRO STUDY; MOUSE; NONHUMAN; ONCOGENE H RAS; OXYGEN ENHANCEMENT RATIO; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY;

EID: 17844385801     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2005.01.019     Document Type: Article

References (40)

1. P. Vaupel, F. Kallinowski, P. Okunieff Blood flow, oxygen consumption and tissue oxygenation of human tumors Adv Exp Med Biol 277 1990 895 905
2. J.M. Brown, A.J. Giaccia The unique physiology of solid tumors Opportunities (and problems) for cancer therapy Cancer Res 58 1998 1408 1416
3. K.S. Yao, M. Clayton, P.J. O'Dwyer Apoptosis in human adenocarcinoma HT29 cells induced by exposure to hypoxia J Natl Cancer Inst 87 1995 117 122
4. S. Shimizu, Y. Eguchi, H. Kosaka Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL Nature 374 1995 811 813
5. C. Schmaltz, P.H. Hardenbergh, A. Wells Regulation of proliferation-survival decisions during tumor cell hypoxia Mol Cell Biol 18 1998 2845 2854
6. T.G. Graeber, J.F. Peterson, M. Tsai Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status Mol Cell Biol 14 1994 6264 6277
7. M.F. Czyzyk-Krzeska Molecular aspects of oxygen sensing in physiological adaptation to hypoxia Respir Physiol 110 1997 99 111
8. T.G. Graeber, C. Osmanian, T. Jacks Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours Nature 379 1996 88 91
9. T. Girinsky, R. Lubin, J.P. Pignon Predictive value of in vitro radiosensitivity parameters in head and neck cancers and cervical carcinomas Preliminary correlations with local control and overall survival Int J Radiat Oncol Biol Phys 25 1993 3 7
10. C.M. West, S.E. Davidson, S.A. Roberts Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix Br J Cancer 68 1993 819 823
11. E.J. Hall Radiobiology for the radiologist Fifth ed. 2000 Lippincott Williams & Wilkins Philadelphia 91 111
12. G.L. Semenza Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis J Lab Clin Med 131 1998 207 214
13. G.L. Wang, B.H. Jiang, E.A. Rue Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension Proc Natl Acad Sci U S A 92 1995 5510 5514
14. L.E. Huang, Z. Arany, D.M. Livingston Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit J Biol Chem 271 1996 32253 32259
15. T. Hofer, I. Desbaillets, G. Hopfl Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1 alpha activation cascade Implications for HIF-1 alpha gene therapy FASEB J 15 2001 2715 2717
16. D. Chilov, G. Camenisch, I. Kvietikova Induction and nuclear translocation of hypoxia-inducible factor-1 (HIF-1) Heterodimerization with ARNT is not necessary for nuclear accumulation of HIF-1alpha J Cell Sci 112 1999 1203 1212
17. B.H. Jiang, G.L. Semenza, C. Bauer Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension Am J Physiol 271 1996 C1172 C1180
18. R.H. Wenger Mammalian oxygen sensing, signalling and gene regulation J Exp Biol 203 2000 1253 1263
19. H. Zhong, A.M. De Marzo, E. Laughner Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases Cancer Res 59 1999 5830 5835
20. R. Bos, H. Zhong, C.F. Hanrahan Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis J Natl Cancer Inst 93 2001 309 314
21. P. Birner, M. Schindl, A. Obermair Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer Cancer Res 60 2000 4693 4696
22. P. Birner, B. Gatterbauer, G. Oberhuber Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas Its impact on prognosis and on neoangiogenesis Cancer 92 2001 165 171
23. D.M. Aebersold, P. Burri, K.T. Beer Expression of hypoxia-inducible factor-1 alpha A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer Cancer Res 61 2001 2911 2916
24. P. Birner, M. Schindl, A. Obermair Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors Its impact on prognosis and on response to chemotherapy Clin Cancer Res 7 2001 1661 1668
25. G. Hopfl, R.H. Wenger, U. Ziegler Rescue of hypoxia-inducible factor-1 alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor Cancer Res 62 2002 2962 2970
26. H.E. Ryan, M. Poloni, W. McNulty Hypoxia-inducible factor-1 alpha is a positive factor in solid tumor growth Cancer Res 60 2000 4010 4015
27. P. Carmeliet, Y. Dor, J.M. Herbert Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis Nature 394 1998 485 490
28. H.E. Ryan, J. Lo, R.S. Johnson HIF-1 alpha is required for solid tumor formation and embryonic vascularization EMBO J 17 1998 3005 3015
29. R.V. LaRocca, M. Rosenblum, B. Westermark Patterns of proto-oncogene expression in human glioma cell lines J Neurosci Res 24 1989 97 106
30. E.P. Clark, H.B. Michaels, E.C. Peterson, E.R. Epp Irradiation of mammalian cells in the presence of diamide and low concentrations of oxygen at conventional and at ultrahigh dose rates Radiat Res 93 1983 479 491
31. G.L. Semenza, P.H. Roth, H.M. Fang Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1 J Biol Chem 269 1994 23757 23763
32. M. Weinmann, C. Belka, L. Plasswilm Tumour hypoxia Impact on biology, prognosis and treatment of solid malignant tumours Onkologie 27 2004 83 90
33. J.M. Brown Tumor hypoxia, drug resistance, and metastases J Natl Cancer Inst 82 1990 338 339
34. J.M. Brown, M.J. Lemmon Tumor hypoxia can be exploited to preferentially sensitize tumors to fractionated irradiation Int J Radiat Oncol Biol Phys 20 1991 457 461
35. J.M. Brown, A.J. Giaccia Tumour hypoxia The picture has changed in the 1990s Int J Radiat Biol 65 1994 95 102
36. V.K. Gupta, N.T. Jaskowiak, M.A. Beckett Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance Cancer J 8 2002 47 54
37. T. Nomiya, K. Nemoto, H. Miyachi Relationships between radiosensitivity and microvascular density in esophageal carcinoma Significance of hypoxic fraction Int J Radiat Oncol Biol Phys 58 2004 589 596
38. J. Dunst, T. Kuhnt, H.G. Strauss Anemia in cervical cancers Impact on survival, patterns of relapse, and association with hypoxia and angiogenesis Int J Radiat Oncol Biol Phys 56 2003 778 787
39. X. Sun, J.R. Kanwar, E. Leung Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy Gene Ther 8 2001 638 645
40. D. Vordermark, A. Katzer, K. Baier Cell type-specific association of hypoxia-inducible factor-1 alpha (HIF-1 alpha) protein accumulation and radiobiologic tumor hypoxia Int J Radiat Oncol Biol Phys 58 2004 1242 1250