Restoration of early rise in plasma insulin levels improves the glucose tolerance of type 2 diabetic patients

Diabetes

Volumn 48, Issue 1, 1999, Pages 99-105

  Bruttomesso, Daniela ^a   Pianta, Alessandro ^a   Mari, Andrea ^b   Valerio, Anna ^a   Marescotti, Maria Cristina ^a   Avogaro, Angelo ^a   Tiengo, Antonio ^a   Del Prato, Stefano ^a,c  

^a UNIVERSITY OF PADOVA   (Italy)

^b CNR   (Italy)

^c Servizio di Diabetologia   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; INSULIN; INSULIN LISPRO; ISOPHANE INSULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GLUCOSE TOLERANCE; HUMAN; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION;

BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCOSE; GLUCOSE TOLERANCE TEST; HUMANS; HYPOGLYCEMIC AGENTS; INJECTIONS, SUBCUTANEOUS; INSULIN; KINETICS; LIPID METABOLISM; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; OXIDATION-REDUCTION; PANCREATIC HORMONES;

EID: 0032941723     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.1.99     Document Type: Article

References (31)

1. Kahn SE, McCulloch DK, Porte D Jr. Insulin secretion in the normal and diabetic human. In The International Textbook of Diabetes Mellitus. 2nd ed., vol. 1. Alberti KGMM, Zimmet P, DeFronzo RA, Eds. 1997, Chichester, U.K., Wiley, p. 337-353
2. Perley MJ, Kipnis DM: Plasma insulin responses to oral and intravenous glucose: studies in normal and diabetic subjects. J Clin Invest 46:1954-1962, 1967
3. Srikanta S, Ganda OP, Gleason PE, Jackson RA, Soeldner JS, Eisenbarth GA: Pre-type I diabetes: linear loss of B-cell response to intravenous glucose. Diabetes 33:717-720, 1984
4. Ward WK, Bogliano DC, McNight JB, Halter JB, Porte D: Diminished B-cell secretory capacity in patients with noninsulin dependent diabetes mellitus. J Clin Invest 76:1318-1328, 1984
5. Bruce DG, Storlien LH, Furler SM, Chisholm DJ: Cephalic phase metabolic responses in normal weight adults. Metabolism 36:721-725, 1987
6. Louise-Silvestre J: Preabsorptive insulin release and hypoglycemia in rats. Am J Physiol 235:56-60, 1976
7. Hommel H, Fischer U, Retzlaff K, Knofler H: The mechanism of insulin secretion after oral glucose administration: II. Reflex insulin secretion in conscious dogs bearing fistulas of the digestive tract by sham-feeding of glucose or tap water. Diabetologia 8:111-116, 1972
8. Kraegen EW, Chisholm DJ, MacNamara M: Timing of insulin delivery with meals. Horm Metab Res 13:365-367, 1981
9. Dimitriadis GD, Gerich JE: Importance of timing of preprandial subcutaneous insulin administration in the management of diabetes mellitus. Diabetes Care 6:374-377, 1983
10. Steiner KE, Mounton SM, Bowles CR, Williams PE, Cherrington AD: The relative importance of first and second-phase insulin secretion in countering the action of glucagon on glucose turnover in the conscious dog. Diabetes 31:964-972, 1982
11. Steiner KE, Mounton SM, Williams PE, Lacy WW, Cherrington AD: Relative importance of first and second-phase insulin secretion in glucose homeostasis in conscious dog: effects on gluconeogenesis. Diabetes 35:776-784, 1986
12. Luzi L, DeFronzo RA: Effects of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans. Am J Physiol 257:E241-E246, 1989
13. Mitrakou A, Kelley D, Veneman T, Jenssen T, Pangburn T, Reilly J, Gerich J: Contribution of abnormal muscle and liver glucose metabolism in postprandial hyperglycemia in NIDDM. Diabetes 39:1381-1390, 1900
14. Firth RG, Bell PM, Marsh HM, Hansen I, Rizza RA: Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus: role of hepatic and extrahepatic tissues. J Clin Invest 77:1525-1532, 1986
15. Ferrannini E, Simonson DC, Karts LD, Reichard G Jr, Bevilacqua S, Barrett EJ, Olsson M, DeFronzo RA: The disposal of an oral glucose load in patients with non-insulin-dependent diabetes. Metabolism 37:79-85, 1988
16. Mitrakou A, Kelley D, Mokan M, Veneman T, Pangburn T, Reilly J, Gerich J: Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance. N Engl J Med 326:22-29, 1992
17. Bruce DG, Chisholm DJ, Storlien LH, Kraegen EW: Physiological importance of deficiency in early prandial insulin secretion in non-insulin-independent diabetes. Diabetes 37:736-744, 1988
18. Holleman F, Hoekstra JBL: Insulin lispro. N Engl J Med 337:176-183, 1997
19. Bonadonna RC, Del Prato S, Bonora E, Gulli G, Solini A, DeFronzo RA: Effects of physiological hyperinsulinemia on the intracellular metabolic partition of plasma glucose. Am J Physiol 265:E943-E953, 1993
20. 2] glucose kinetics. Diabetes 38:845-853, 1989
21. Miles JR, Glassock J, Aikens J, Gerich J, Haymond M: A microfluorimetric method for the determination of free fatty acids in plasma. J Lipid Res 24:96-99, 1983.
22. Ferrannini E, Del Prato S, DeFronzo RA: Glucose kinetics. Tracer methods. In Methods in Diabetes Research, vol. 2. Clarke WL, Larner J, Pohl SL, Eds. Chichester, U.K., Wiley, 1986, p. 107-141
23. Mari A: Estimation of the rate of appearance in the non-steady state with a two-comportment model. Am J Physiol 263:E400-E415, 1992
24. Mari A, Wahren J, DeFronzo RA, Ferrannini E: Glucose absorption and production following oral glucose: comparison of compartmental and arteriovenous-difference methods. Metabolism 43:1419-1425, 1994
25. 13C] glucose. Am J Physiol 245:E476-E482, 1983
26. Ferrannini E: The theoretical bases of indirect calorimetry: a review. Metabolism 37:287-301, 1988
27. Groop LC, Bonadonna RC, Del Prato S, Ratheiser K, Zyck K, Ferrannini E, DeFronzo RA: Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. J Clin Invest 84:205-213, 1989
28. Reaven GM, Chen Y-DI, Golay A, Swislocki M, Jaspan JB: Documentation of hyperglucagonemia throughout the day in nonobese patients with non-insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 64:106-110, 1987
29. Del Prato S, Leonetti F, Simonson DC, Sheean P, DeFronzo RA: Effect of chronic physiologic hyperinsulinemia and hyperglycemia on insulin secretion and insulin sensitivity in man. Diabetologia 30:1025-1035, 1994
30. DeFronzo RA, Ferrannini E: Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194, 1991
31. Del Prato S, Bonadonna RC, Bonora E, Gulli G, Solini A, Shank M, DeFronzo RA: Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus. J Clin Invest 91:484-494, 1993