Local growth factors are beneficial for the autonomic reinnervation of transplanted islets in rats

Pancreas

Volumn 26, Issue 4, 2003, Pages 392-397

  Reimer, Martina Kvist ^a   Mokshagundam, Sri Prakash ^b   Wyler, Karen ^b   Sundler, Frank ^a   Ahrén, Bo ^a,c   Stagner, John I ^b  

^a LUND UNIVERSITY   (Sweden)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Autonomic nerves; Diabetes; Graft; Nerve growth factor; Neuropeptides; Rat; Transplantation; Vascular endothelial growth factor

Indexed keywords

GROWTH FACTOR; NERVE GROWTH FACTOR; NEUROPEPTIDE Y; TYROSINE 3 MONOOXYGENASE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC INNERVATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; GRAFT SURVIVAL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; NONHUMAN; PANCREAS FUNCTION; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RAT; REINNERVATION; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; FASTING; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; NERVE GROWTH FACTOR; NEUROPEPTIDE Y; RATS; RATS, INBRED LEW; TYROSINE 3-MONOOXYGENASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 0037730407     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-200305000-00014     Document Type: Article

References (35)

1. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343:230-238.
2. Ryan EA, Lakey JR, Rajotte RV, et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes 2001;50:710-719.
3. Korsgren O, Andersson A, Jansson L, et al. Reinnervation of transplanted mouse pancreatic islets. Transplant Proc 1991;23:750-751.
4. Korsgren O, Jansson L, Andersson A, Sundler F. Reinnervation of transplanted pancreatic islets: a comparison among islets implanted into the kidney, spleen, and liver. Transplantation 1993;56:138-143.
5. Henriksson C, Claes G, Pehrsson NG. Viability of the islets of Langerhans after warm ischemia as judged by isologous transplantation. Acta Chir Scand 1977;143:323-328.
6. Mandel TE, Koulmanda M. Effect of ischemia and temperature on fetal mouse pancreas. Insulin production in vitro, and function after isotransplantation. Diabetes 1984;33:376-382.
7. Stagner JI, Mokshagundam S, Samols E. Hormone secretion from transplanted islets is dependent upon changes in islet revascularization and islet architecture. Transplant Proc 1995;27:3251-3254.
8. Allen JM, Polak JM, Bloom SR. Presence of the predicted C-flanking peptide of neuropeptide Y (CPON) in tissue extracts. Neuropeptides 1985;6:95-100.
9. Ahren B. Autonomic regulation of islet hormone secretion: implications for health and disease. Diabetologia 2000;43:393-410.
10. Korsgren O, Jansson L, Andersson A, et al. Reinnervation of transplanted pancreatic islets: a comparison between islets implanted into the kidney, spleen, or liver. Transplant Proc 1992;24:1025-1026.
11. Persson-Sjögren S, Forsgren S, Taljedal IB. Peptides and other neuronal markers in transplanted pancreatic islets. Peptides 2000;21:741-752.
12. Persson-Sjögren S, Forsgren S, Taljedal IB. Expression of tyrosine hydroxylase, calcitonin gene-related peptide, substance P and protein gene product 9.5 in mouse islets transplanted under the kidney capsule. Neuropeptides 1998;32:307-318.
13. Shi CL, Sehlin J, Taljedal IB. Effects of UK-14,304, noradrenaline, and propranolol on insulin release from transplanted mouse islets. Eur J Endocrinol 1996;135:724-728.
14. Lindskog S, Ahrén B, Dunning BE, et al. Galanin-immunoreactive nerves in the mouse and rat pancreas. Cell Tissue Res 1991;264:363-368.
15. Ekström AR, Kanje M, Skottner A. Nerve regeneration and serum levels of insulin-like growth factor-I in rats with streptozotocin-induced insulin deficiency. Brain Res 1989;496:141-147.
16. Korsgren O, Andersson A, Jansson L, et al. Reinnervation of syngeneic mouse pancreatic islets transplanted into renal subcapsular space. Diabetes 1992;41:130-135.
17. Mohiuddin L, Tomlinson DR. Impaired molecular regenerative responses in sensory neurones of diabetic rats: gene expression changes in dorsal root ganglia after sciatic nerve crush. Diabetes 1997;46:2057-2062.
18. Myrsen U, Keymeulen B, Pipeleers DG, et al. Beta cells are important for islet innervation: evidence from purified rat islet-cell grafts. Diabetologia 1996;39:54-59.
19. Scharfmann R, Tazi A, Polak M, et al. Expression of functional nerve growth factor receptors in pancreatic beta-cell lines and fetal rat islets in primary culture. Diabetes 1993;42:1829-1836.
20. Pierucci D, Cicconi S, Bonini P, et al. NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro. Diabetologia 2001;44:1281-1295.
21. Rosenbaum T, Vidaltamayo R, Sanchez-Soto MC, et al. Pancreatic beta cells synthesize and secrete nerve growth factor. Proc Natl Acad Sci U S A 1998;95:7784-7788.
22. Kanaka-Gantenbein C, Tazi A, Czernichow P, et al. In vivo presence of the high affinity nerve growth factor receptor Trk- A in the rat pancreas: differential localization during pancreatic development. Endocrinology 1995;136:761-769.
23. Yamaoka T, Itakura M. Development of pancreatic islets [review]. Int J Mol Med 1999;3:247-261.
24. Rosenbaum T, Vidaltamayo R, Sanchez-Herrera D, et al. Nerve growth factor increases sodium current in pancreatic beta cells. J Membr Biol 1996:153:53-58.
25. Rosenbaum T, Sanchez-Soto MC, Hiriart M. Nerve growth factor increases insulin secretion and barium current in pancreatic beta-cells. Diabetes 2001;50:1755-1762.
26. Grodsky GM, Ma YH, Edwards RH. Chronic sympathetic innervation of islets in transgenic mice results in differential desensitization of alpha-adrenergic inhibition of insulin secretion. Adv Exp Med Biol 1997;426:129-138.
27. Klein R. Role of neurotrophins in mouse neuronal development. Faseb J 1994;8:738-744.
28. Lewin GR, Rueff A, Mendell LM. Peripheral and central mechanisms of NGF-induced hyperalgesia. Eur J Neurosci 1994;6:1903-1912.
29. Olson L. Outgrowth of sympathetic adrenergic neurons in mice treated with a nerve-growth factor (NGF). Z Zellforsch Mikrosk Anat 1967;81:155-173.
30. Angeletti PU, Levi-Montalcini R. Growth regulation of the sympathetic nervous system: immunosympathectomy and chemical sympathectomy. Rev Eur Etud Clin Biol 1971;16:866-874.
31. Bjerre B, Bjorklund A, Mobley W, Rosengren E. Short- and long-term effects of nerve growth factor on the sympathetic nervous system in the adult mouse. Brain Res 1975;94:263-277,
32. Christofori G, Naik P, Hanahan D. Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis. Mol Endocrinol 1995;9:1760-1770.
33. Aase K, Lymboussaki A, Kaipainen A, et al. Localization of VEGF-B in the mouse embryo suggests a paracrine role of the growth factor in the developing vasculature. Dev Dyn 1999;215:12-25.
34. Oberg-Welsh C, Sandler S, Andersson A, et al. Effects of vascular endothelial growth factor on pancreatic duct cell replication and the insulin production of fetal islet-like cell clusters in vitro. Mol Cell Endocrinol 1997;126:125-132.
35. Kuroda M, Oka T, Oka Y, et al. Colocalization of vascular endothelial growth factor (vascular permeability factor) and insulin in pancreatic islet cells. J Clin Endocrinol Metab 1995;80:3196-3200.