Augmentation of Helicobacter pylori urease activity by its specific IgG antibody: Implications for bacterial colonization enhancement

Biomedical Research

Volumn 26, Issue 1, 2005, Pages 35-42

  Iizumi, Tadasu ^a   Yamanishi, Shingo ^a   Kumagai, Yoshihiro ^a   Nagata, Kumiko ^b   Kamiya, Shigeru ^c   Hirota, Kaoru ^a   Watanabe, Eri ^a   Sakamoto, Choitsu ^a   Takahashi, Hidemi ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; UREASE; BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; MONOCLONAL ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; COLONY FORMING UNIT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELICOBACTER PYLORI; IN VIVO STUDY; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STOMACH MUCOSA; WESTERN BLOTTING; ANIMAL; ANTIBODY SPECIFICITY; BAGG ALBINO MOUSE; ENZYMOLOGY; EPITOPE MAPPING; GASTRITIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; HELICOBACTER INFECTION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS;

ANIMALIA; BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGENS, BACTERIAL; EPITOPE MAPPING; FEMALE; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; UREASE;

EID: 17844369166     PISSN: 03886107     EISSN: 1880313X     Source Type: Journal    
DOI: 10.2220/biomedres.26.35     Document Type: Article

References (25)

1. Akhiani AA, Pappo J, Kabok Z, Schon K, Gao W, Franzen LE and Lycke N (2002) Protection against Helicobacter pylori infection following immunization is IL-12-dependent and mediated by Th1 cells. J Immunol 169, 6977-6984.
2. Akhiani AA, Schon K, Franzen LE, Pappo J and Lycke N (2004) Helicobacter pylori-specific antibodies impair the development of gastritis, facilitate bacterial colonization, and counteract resistance against infection. J Immunol 172, 5024-5033.
3. Blanchard TG, Czinn SJ, Redline RW, Sigmund N, Harriman G and Nedrud JG (1999) Antibody-independent protective mucosal immunity to gastric helicobacter infection in mice. Cell Immunol 191, 74-80.
4. Blaser MJ (1990) Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis 161, 626-633.
5. Bunn, JE, Thomas JE, Harding M, Coward WA and Weaver LT (2003) Placental acquisition of maternal specific IgG and Helicobacter pylori colonization in infancy. Helicobacter 8, 568-572.
6. Chen W, Shu D and Chadwick VS (2001) Helicobacter pylori infection: mechanism of colonization and functional dyspepsia reduced colonization of gastric mucosa by Helicobacter pylori in mice deficient in interleukin-10. J Gastroenterol Hepatol 16, 377-383.
7. Eaton KA, Brooks CL, Morgan DR and Krakowka S (1991) Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets. Infect Immun 59, 2470-2475.
8. Eaton KA and Krakowka S (1994) Effect of gastric pH on urease-dependent colonization of gnotobiotic piglets by Helicobacter pylori. Infect Immun 62, 3604-3607.
9. Ermak TH, Giannasca PJ, Nichols R, Myers GA, Nedrud J, Weltzin R. Lee CK, Kleanthous H and Monath TP (1998) Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of anti-bodies and is mediated by MHC class II-restricted responses, J Exp Med 188, 2277-2288.
10. Fan, X, Crowe SE, Behar S, Gunasena H, Ye G, Haeberle H, Van Houten N, Gourley WK, Ernst PB and Reyes VE (1998) The effect of class II major histocompatibility complex expression on adherence of Helicobacter pylori and induction of apoptosis in gastric epithelial cells: a mechanism for T helper cell type 1-mediated damage. J Exp Med 187:1659-1669.
11. Fan X, Gunasena H, Cheng Z, Espejo R, Crowe SE, Ernst PB, and Reyes VE (2000) Helicobacter pylori urease binds to class II MHC on gastric epithelial cells and induces their apoptosis. J Immunol 165, 1918-1924.
12. Futagami S, Takahashi H, Norose Y and Kobayashi M (1998) Systemic and local immune responses against Helicobacter pylori urease in patients with chronic gastritis: distinct IgA and IgG productive sites. Gut 43, 168-175.
13. Futagami S, Takahashi H, Norose Y, Nagata K, Kobayashi M and Nomura T (1994) Analysis of immune response to Helicobacter pylori-identification of the protein recognized by anti-Helicobacter pylori antibodies from sera of patients with gastroduodenal diseases. Nippon Shokakibyo Gakkai Zasshi 91, 2202-2213.
14. Gold BD, Khanna B, Huang LM, Lee CY and Banatvala N (1997) Helicobacter pylori acquisition in infancy after decline of maternal passive immunity. Pediatr Res 41, 641-646.
15. Ha NC, Oh ST, Sung JY, Cha KA, Lee MH and Oh BH (2001) Supramolecular assembly and acid resistance of Helicobacter pylori urease. Nat Struct Biol 8, 505-509.
16. Hirota K, Nagata K, Norose Y, Futagami S, Nakagawa Y, Senpuku H, Kobayashi M and Takahashi H (2001) Identification of an antigenic epitope in Helicobacter pylori urease that induces neutralizing antibody production. Infect Immun 69, 6597-6603.
17. Hussell T, Isaacson PG, Crabtree JE and Spencer J (1993) The response of cells from low-grade B-cell gastric lymphomas of mucosa-asiociated lymphoid tissue to Helicobacter pylori. Lancet 342, 571-574.
18. Jiang B, Jordana M, Xing Z, Smaill F, Snider DP, Borojevic R, Steele-Norwood D, Hunt RH and Croitoru K (1999) Replication-defective adenovirus infection reduces Helicobacter felis colonization in the mouse in a gamma interferon- and interleukin-12-dependent manner. Infect Immun 67, 4539-4544.
19. Kopec LK, Vacca Smith AM, Wunder D, Ng-Evans L and Bowen WH (2002) Influence of antibody on the structure of glucans. Caries Res 36, 108-115.
20. Lee A, O'Rourke J, De Ungria MC, Robertson B, Daskalopoulos G and Dixon MF (1997) A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain. Gastroenterology 112, 1386-1397.
21. Nagata K, Mizuta T, Tonokatu Y, Fukuda Y, Okamura H, Hayashi Shimoyama T and Tamura T (1992) Monoclonal antibodies against the native urease of Helicobacter pylori: synergistic inhibition of urease activity by monoclonal antibody combinations. Infect Immun 60, 4826-4831.
22. Nolan KJ, McGee DJ, Mitchell HM, Kolesnikow T, Harro JM, O'Rourke J, Wilson JE, Danon SJ, Moss ND, Mobley HL and Lee A (2002) In vivo behavior of a Helicobacter pylori SS1 nixA mutant with reduced urease activity, Infect Immun 70, 685-691.
23. Panthel K, Faller G and Haas R (2003) Colonization of C57BL/6J and BALB/c wild-type and knockout mice with Helicobacter pylori: effect of vaccination and implications for innate and acquired immunity. Infect Immun 71, 794-800.
24. Sutton P and Lee A 2000. Review article: Helicobacter pylori vaccines-the current status. Aliment Pharmacol Ther 14, 1107-1118.
25. Thomas JE, Dale A, Harding M, Coward WA, Cole TJ and Weaver LT (1999) Helicobacter pylori colonization in early life. Pediatr Res 45, 218-223.