Effect of Aronia melanocarpa fruit juice on indomethacin-induced gastric mucosal damage and oxidative stress in rats

Experimental and Toxicologic Pathology

Volumn 56, Issue 6, 2005, Pages 385-392

  Valcheva Kuzmanova, S ^a   Marazova, K ^a,b   Krasnaliev, I ^a   Galunska, B ^a   Borisova, P ^a   Belcheva, A ^a  

^a MEDICAL UNIVERSITY OF VARNA   (Bulgaria)

^b HÔPITAL BROUSSAIS   (France)

Author keywords

Antioxidant activity; Aronia melanocarpa; Gastric mucosal damage; Indomethacin; Lipid peroxidation; Oxidative stress

Indexed keywords

ARONIA MELANOCARPA EXTRACT; GLUTATHIONE TRANSFERASE; INDOMETACIN; MALONALDEHYDE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARONIA MELANOCARPA; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; HISTOPATHOLOGY; MALE; MEDICINAL PLANT; MORPHOMETRICS; NONHUMAN; OXIDATION; OXIDATIVE STRESS; RAT; STOMACH MUCOSA; STOMACH MUCOSA LESION;

ARONIA; PHOTINIA MELANOCARPA;

EID: 17844366816     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2005.01.001     Document Type: Article

References (30)

1. D.L.L.C. Alarcon, M.J. Martin, and C. LaCasa Antiulcerogenic activity of flavonoids and gastric protection J Ethnopharmacol 42 1994 161 170
2. W. Beil, C. Birkholz, and K.F. Sewing Effects of flavonoids on parietal cell acid secretion, gastric mucosal prostaglandin production and Helicobacter pylori growth Arzneim Forsch 45 1995 697 700
3. K.N. Chidambara Murthy, G.K. Jayaprakasha, and R.P. Singh Studies on antioxidant activities of pomegranate (Punica granatum) peel extract using in vivo models J Agric Food Chem 50 2002 4791 4795
4. K.D. Das, and R.K. Banerjee Effect of stress on the antioxidant enzymes and gastric ulceration Mol Cell Biochem 125 1993 115 125
5. G.R. Davis, N.J. Simmonds, and N.J. Stevens Helocobacter pylori stimulates antral mucosal reactive metabolite production in vivo Gut 35 1994 179 185
6. R. Hernandez-Munoz, C. Montiel-Ruiz, and O. Vazquez-Martinez Gastric mucosal cell proliferation in ethanol-induced chronic mucosal injury is related to oxidative stress and lipid peroxidation in rats Lab Invest 80 2000 1161 1169
7. P. Hissin, and A. Hilf A fluorimetric method for determination of oxidized and reduced glutathione in tissues Annal Biochem 74 1986 214 226
8. M.T. Khayyal, M.A. el-Ghalazy, and S.A. Kenawy Antiulcerogenic effect of some gastrointestinally acting plant extracts and their combination Arzneim Forsch 51 2001 545 553
9. E. Kowalczyk, A. Kopff, and J. Niedworok Anthocyanins - an adjunct to cardiovascular therapy? Kadiologia Polska 57 2002 332 334
10. C. La Casa, I. Villegas, and C. Alarcon de la Lastra Evidence of protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions J Ethnopharamacol 71 2000 45 53
11. M.J. Magistretti, M. Conti, and A. Cristoni Anti-ulcer activity of an anthocyanidin from Vaccinium myrtillus (bilberry) fruits and cell cultures Plant Sci 131 1988 95 103
12. M.J. Martin, C. La-Casa, and C. Alarcon-de-la-Lastra Anti-oxidant mechanisms involved in gastroprotective effects of quercetin Z Naturforsch [C] 53 1998 82 88
13. Y. Naito, T. Yoshikawa, and N. Yoshida Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury Dig Dis Sci 43 1998 30S 34S
14. Y. Noda, T. Kaneyuki, and A. Mori Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin J Agric Food Chem 50 2002 166 171
15. J. Oszmiański, and J.C. Sepia Anthocyanins in fruits of Aronia Melanocarpa (Chokeberry) J Food Sci 53 1988 1241 1242
16. N.S. Parmar The gastric anti-ulcer activity of naringenin, a specific histidine decarbohylase inhibitor Int J Tissue React 4 1983 415 420
17. C. Perez-Guerrero, M.J. Martin, and E. Marhuenda Prevention by rutin of gastric lesions induced by ethanol in rats: role of endogenous prostaglandins Gen Pharmacol 25 1994 575 580
18. G. Pihan, C. Regillo, and S. Szabo Free radicals and lipid peroxidation in ethanol- and aspirin-induced gastric mucosal injury Dig Dis Sci 32 1987 1395 1401
19. N. Porter, J. Norton, and J. Ramdas Cyclic peroxidase and thiobarbituric assay Biochem Biophys Acta 441 1976 596 599
20. Q.H.M. Saad, N.M. Kassim, and G.M. Top Tocotrienol-rich fraction and its effects on parameters affecting gastric mucosal integrity after a single exposure to indomethacin Pakistan J Nutr 1 2002 89 92
21. 2 metabolism Gut 33 1992 164 169
22. J. Tanaka, and Y. Yuda Role of lipid peroxidation in gastric mucosal lesions induced by ischemia-reperfusion in the pylorus-ligated rat Biol Pharm Bull 16 1993 29 32
23. J. Tanaka, and Y. Yuda Lipid peroxidation in gastric mucosal lesions induced by indomethacin in rat Biol Pharm Bull 19 1996 716 720
24. T. Tsuda, K. Shiga, and K. Oshima Inhibition of lipid peroxidation and the active oxygen radical scavenging effect of anthocyanin pigments isolated from Phaseolus vulgaris L Biochem Pharmacol 52 1996 1033 1039
25. H. Wang, M.G. Nair, and G.M. Strasburg Antioxidant and anti-inflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries J Nat Prod 62 1999 294 296
26. B.J.R. Whittle Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis and the gastrointestinal damage induced by indomethacin in the rat Gastroenterol 80 1981 81 94
27. B.R. Whittle The defensive role played by the gastric microcirculation Methods Find Exp Clin Pharmacol 11 Suppl 1 1989 35S 43S
28. H. Yamasaki, H. Uefuji, and Y. Sakihama Bleaching of the red anthocyanin induced by superoxide radical Arch Biochem Biophys 332 1996 183 186
29. T. Yoshikawa, Y. Naito, and A. Kishi Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats Gut 34 1993 732 737
30. W. Zheng, and S. Wang Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries J Agric Food Chem 51 2003 502 509