Successful therapeutic effect in a mouse model of erythropoietic protoporphyria by partial genetic correction and fluorescence-based selection of hematopoietic cells

Gene Therapy

Volumn 8, Issue 8, 2001, Pages 618-626

  Fontanellas, A ^a,b   Mendez, M ^a   Mazurier, F ^a   Cario Andre M ^a   Navarro, S ^b   Ged, C ^a   Taine, L ^a,c   Geronimi F ^a   Richard, E ^a   Moreau Gaudry, F ^a   Enriquez De Salamanca, R ^b   De Verneuil, H ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^c HÔPITAL PELLEGRIN   (France)

Author keywords

Animal model; Bone marrow; Cutaneous photosensitivity; Gene transfer; Genetic disease; Porphyria; Retrovirus

Indexed keywords

COMPLEMENTARY DNA; FERROCHELATASE; PROTOPORPHYRIN; VIRUS VECTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BONE MARROW CELL; CELL SELECTION; CELL TRANSPLANTATION; CLINICAL PROTOCOL; CONTROLLED STUDY; DNA MODIFICATION; ENZYME DEFICIENCY; ERYTHROCYTE; ERYTHROCYTE COUNT; ERYTHROPOIETIC PROTOPORPHYRIA; FLUORESCENCE; FLUORESCENCE ACTIVATED CELL SORTER; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HEMATOPOIESIS; HEMATOPOIETIC CELL; ILLUMINATION; IN VITRO STUDY; INJECTION; MARKER GENE; MOUSE; NONHUMAN; ORGAN; PHENOTYPE; PHOTOSENSITIVITY; PLASMA; PRIORITY JOURNAL; RETROVIRUS; SKIN SENSITIVITY; ULTRAVIOLET RADIATION;

ANIMALIA; MURINAE; UNIDENTIFIED RETROVIRUS;

EID: 17744383358     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301427     Document Type: Article

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