Spectrum of antiviral activity of o-(acetoxyphenyl)hept-2-ynyl sulphide (APHS)

International Journal of Antimicrobial Agents

Volumn 25, Issue 5, 2005, Pages 419-426

  Pereira, Cândida F ^a   Rutten, Karla ^a   Stránská, Růžena ^a   Huigen, Marleen C D G ^a   Aerts, Piet C ^a   De Groot, Raoul J ^b   Egberink, Herman F ^b   Schuurman, Rob ^a   Nottet, Hans S L M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Antiherpetic; Antiviral; APHS; Drug resistance; HIV; HSV

Indexed keywords

2 (ACETOXYPHENYL)HEPT 2 YNYLSULFIDE; ACICLOVIR; NONSTEROID ANTIINFLAMMATORY AGENT; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FELINE IMMUNODEFICIENCY VIRUS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RNA VIRUS; VIRUS REPLICATION; VIRUS STRAIN;

EID: 17644401316     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2004.11.011     Document Type: Article

References (36)

1. E. De Clercq 2001 ASPET Otto Krayer Award Lecture. Molecular targets for antiviral agents J Pharmacol Exp Ther 297 2001 1 10
2. C.S. Crumpacker Mechanism of action of foscarnet against viral polymerases Am J Med 92 1992 3S 7S
3. TachedjianG, D.J. Hooker, and A.D. Gurusinghe Characterisation of foscarnet-resistant strains of human immunodeficiency virus type 1 Virology 212 1995 58 68
4. E. De Clercq, A. Holy, I. Rosenberg, T. Sakuma, J. Balzarini, and P.C. Maudgal A novel selective broad-spectrum anti-DNA virus agent Nature 323 1986 464 467
5. T.W. Vahlenkamp, A. de Ronde, and J. Balzarini (R)-9-(2- Phosphonylmethoxypropyl)-2,6-diaminopurine is a potent inhibitor of feline immunodeficiency virus infection Antimicrob Agents Chemother 39 1995 746 749
6. L. Naesens, J. Balzarini, and E. de Clercq The potential of acyclic nucleoside phosphonates as broad-spectrum antiviral agents Postepy Biochem 41 1995 347 351
7. H. Jonckheere, J. Anne, and E. De Clercq The HIV-1 reverse transcription (RT) process as target for RT inhibitors Med Res Rev 20 2000 129 154
8. C.F. Pereira, J.T. Paridaen, and K. Rutten Aspirin-like molecules that inhibit human immunodeficiency virus 1 replication Antiviral Res 58 2003 253 263
9. M. Guyader, M. Emerman, P. Sonigo, F. Clavel, L. Montagner, and M. Alizon Genome organization and transactivation of the human immunodeficiency virus type 2 Nature 326 1987 662 669
10. H. Egberink, M. Borst, and H. Niphuis Suppression of feline immunodeficiency virus infection in vivo by 9-(2-phosphonomethoxyethyl)adenine Proc Natl Acad Sci USA 87 1990 3087 3091
11. K. Hartmann Feline immunodeficiency virus infection - causative agent of an acquired immunodeficiency syndrome in cats Eur J Med Res 1 1996 547 550
12. T.W. North, R.C. Cronn, K.M. Remington, and R.T. Tandberg Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses Antimicrob Agents Chemother 34 1990 1505 1507
13. P.L. Ogra Respiratory syncytial virus: the virus, the disease and the immune response Paediatr Respir Rev 5 (Suppl. A) 2004 S119 S126
14. S.A. Stohlman, C.C. Bergmann, and S. Perlman Mouse hepatitis virus R. Ahmed I. Chen Persistent viral infections 1998 Wiley New York, USA 537 557
15. D.O. White FJ. Fenner Herpesviridae. Medical virology 4th ed. 1994 Academic Press San Diego, USA 317 347
16. E.C. Stabell, and P.D. Olivo Isolation of a cell line for rapid and sensitive histochemical assay for the detection of herpes simplex virus J Virol Meth 38 1992 195 204
17. S.M. Owen, D. Ellenberger, and M. Rayfield Genetically divergent strains of human immunodeficiency virus type 2 use multiple coreceptors for viral entry J Virol 72 1998 5425 5432
18. J.H. Nunberg, W.A. Schleif, and E.J. Boots Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors J Virol 65 1991 4887 4892
19. SpaanWJ, P.J. Rottier, M.C. Horzinek, and B.A. van der Zeijst Isolation and identification of virus-specific mRNAs in cells infected with mouse hepatitis virus (MHV-A59) Virology 108 1981 424 434
20. J.S. Gibbs, H.C. Chiou, K.F. Bastow, ChengYC, and D.M. Coen Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition Proc Natl Acad Sci USA 85 1988 6672 6676
21. D.M. Coen, H.E. Fleming Jr., L.K. Leslie, and M.J. Retondo Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus J Virol 53 1985 477 488
22. A.I. Marcy, C.B. Hwang, K.L. Ruffner, and D.M. Coen Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition J Virol 64 1990 5883 5890
23. F. Morfin, D. Thouvenot, G. Souillet, M. Michallet, and M. Aymard Aciclovir-resistant (ACV-R) herpes viruses (HSV, VZV) in bone marrow transplantation patients Acta Microbiol et Immunol Hungarica 46 1999 429
24. P.A. Schaffer, G.M. Aron, N. Biswal, and M. Benyesh-Melnick Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization Virology 52 1973 57 71
25. A.S. Kalgutkar, K.R. Kozak, B.C. Crews, Hochgesang GPJ, and L.J. Marnett Covalent modification of cyclooxygenase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators J Med Chem 41 1998 4800 4818
26. R. Pauwels, J. Balzarini, and M. Baba Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds J Virol Meth 20 1988 309 321
27. H.F. Egberink, C.E. Keldermans, M.J. Koolen, and M.C. Horzinek Humoral immune response to feline immunodeficiency virus in cats with experimentally induced and naturally acquired infections Am J Vet Res 53 1992 1133 1138
28. J.A. McKeating, A. McKnight, and J.P. Moore Differential loss of envelope glycoprotein gp120 from virions of human immunodeficiency virus type 1 isolates: effects on infectivity and neutralization J Virol 65 1991 852 860
29. J.P. Moore, J.A. McKeating, R.A. Weiss, and Q.J. Sattentau Dissociation of gp120 from HIV-1 virions induced by soluble CD4 Science 250 1990 1139 1142
30. ® HSV, a yield reduction assay for rapid herpes simplex virus susceptibility testing Antimicrob Agents Chemother 48 2004 2331 2333
31. T.C. Chou, and P. Talalay Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors Adv Enzyme Regul 22 1984 27 55
32. Chou TC, Hayball MP. Cambridge, UK: BIOSOFT, 1996.
33. J. Auwerx, T.W. North, B.D. Preston, G.J. Klarman, E. de Clerq, and J. Balzarini Chimeric human immunodeficiency virus type 1 and feline immunodeficiency virus reverse transcriptases: role of the subunits in resistance/sensitivity to non-nucleoside reverse transcriptase inhibitors Mol Pharmacol 61 2002 400 406
34. C.F. Pereira, J.T. Paridaen, M. van de Bovenkamp, J. Middel, J. Verhoef, and H.S. Nottet APHS can act synergically with clinically available HIV-1 reverse transcriptase and protease inhibitors and is active against several drug-resistant HIV-1 strains in vitro J Antimicrob Chemother 51 2003 1181 1189
35. M.P. Wentland, R.B. Perni, and P.H. Dorff Antiviral properties of 3-quinolinecarboxamides: a series of novel non-nucleoside antiherpetic agents Drug Des Discov 15 1997 25 38
36. T.E. Renau, L.L. Wotring, J.C. Drach, and L.B. Townsend Synthesis of non-nucleoside analogs of toyocamycin, sangivamycin, and ++thiosangivamycin: influence of various 7-substituents on antiviral activity J Med Chem 39 1996 873 880