5-HT(2A) receptors stimulate mitogen-activated protein kinase via H2O2 generation in rat renal mesangial cells

American Journal of Physiology - Renal Physiology

Volumn 278, Issue 4 47-4, 2000, Pages

  Greene, Eddie L ^a,b   Houghton, Odette ^a   Collinsworth, Georgiann ^a   Garnovskaya, Maria N ^a   Nagai, Toshio ^a   Sajjad, Tahir ^a   Bheemanathini, Venugopala ^a   Grewal, Jasjit S ^a   Paul, Richard V ^a   Raymond, John R ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Kidney; NADP(H) oxidase; Reactive oxygen species; Serotonin receptor; Signal transduction

Indexed keywords

HYDROGEN PEROXIDE; KETANSERIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SEROTONIN; SEROTONIN 2A RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

EID: 17544370809     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2000.278.4.f650     Document Type: Article

References (43)

1. Abboud HE. Histamine and serotonin. In: Renal Endocrinology, edited by Dunn MJ. New York: Spectrum, 1986, vol. 1, p. 429-461.
2. Abe J and Berk BC. Reactive oxygen species as mediators of signal transduction in cardiovascular disease. Trends Cardiovasc Med 8: 59-64, 1998.
3. Aikawa R, Komuro I, Yamazaki T, Zou Y, Y, Kudoh S, Tanaka M, Shiojima I, Hiroi Y, and Yazaki Y. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest 100: 1813-1821, 1997.
4. Ausiello DA, Kreisberg JI, Roy C, and Karnovsky MJ. Contraction of cultured rat glomerular cells of apparent mesangial origin after stimulation with ANG II and arginine vasopressin. J Clin Invest 65: 754-760, 1980.
5. Ayo SH, Radnik R, Garoni JA, Troyer DA, and Kreisberg JI. High glucose increases diacylglycerol mass and activates protein kinase C in mesangial cell cultures. Am J Physiol Renal Fluid Electrolyte Physiol 261: F571-F577, 1991.
6. Bokemeyer D, Guglielmi KE, McGinty A, Sorokin A, Lianos EA, and Dunn M. Activation of extracellular signal-regulated kinases in proliferative glomerulonephritis in rats. J Clin Invest 100: 1813-1821, 1997.
7. Bonventre JV, Skorecki K, Kreisberg JI, and Cheung JY. Vasopressin increases cytosolic free calcium concentration in glomerular mesangial cells. Am J Physiol Renal Fluid Electrolyte Physiol 251: F94-F102, 1986.
8. Carter W, Narayanan PK, and Robinson JP. Intracellular detection of hydrogen peroxide and superoxide detection in endothelial cells. J Leukocyte Biol 55: 253-258, 1994.
9. Chanock SJ, El Benna J, Smith RM, and Babior B. The respiratory burst oxidase. J Biol Chem 269: 24519-24522, 1995.
10. Chen Q, Olashaw N, and Wu J. Participation of reactive oxygen species in the lysophosphatidic acid-stimulated mitogen-activated protein kinase activation pathway. J Biol Chem 270: 28499-28502, 1995.
11. Cross AR. Inhibitors of the leukocyte superoxide-generating oxidase. Free Radic Biol Med 8: 71-93, 1990.
12. Dean RT, Fu S, Stocker R, and Davies MJ. Biochemistry and pathology of radical-mediated protein oxidation. Biochem. J 324: 1-18, 1997.
13. Diatchuk V, Lotan O, Koshkin V, Wikstroem P, and Pick E. Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)benzenesulfonyl fluoride. J Biol Chem 272: 13292-13301, 1997.
14. Fialkow L, Chin CK, Rotin D, Grinstein S, and Downey GP. Activation of the mitogen-activated protein kinase signaling pathway in neutrophils. J Biol Chem 269: 31234-31242, 1994.
15. Fenton HJH. Oxidation of tartaric acid in the presence of iron. J Chem Soc 65: 899-910, 1894.
16. 2A receptors expressed in rat renal mesangial cells inhibit cyclic AMP accumulation. Mol Pharmacol 48: 230-237, 1995.
17. 1A receptor via a G protein βγ-subunit-initiated pathway. Biochemistry 35: 13716-13722, 1996.
18. Greiber S, Munzel T, Kastner S, Muller B, Schollmeyer P, and Pavenstadt H. NAD(P)H oxidase activity in cultured human podocytes: effects of adenosine triphosphate. Kidney Int 53: 654-663, 1998.
19. 1 expression in mesangial cells via ERL: proliferative and fibrotic signals. Am J Physiol Renal Physiol 276: F922-F930, 1999.
20. Griffith OW and Meister A. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem 254: 7558-7560, 1979.
21. Jones SA, Hancock JT, Jones OTG, Neubauer A, and Topley N. The expression of NADPH oxidase components in human glomerular mesangial cells. J Am Soc Nephrol 5: 1483-1491, 1995.
22. Knauss T and Abboud HE. Effects of serotonin on prostaglandin synthesis in rat cultured mesangial cells. Am J Physiol Renal Fluid Electrolyte Physiol 251: F844-F850, 1986.
23. Kosower NS and Kosower EM. Diamide: an oxidant probe for thiols. Methods Enzymol 251: 123-133, 1995.
24. Le Cabec V and Maridonneau-Parini I. Complete and reversible inhibition of NADPH oxidase in human neutrophils by phenylarsine oxide at a step distal to membrane translocation of the enzyme subunits. J Biol Chem 270: 2067-2073, 1995.
25. Lee S-H, Wang WW, Finlay GA, and Fanburg BL. Serotonin stimulates mitogen-activated protein kinase through the formation of superoxide anion. Am J Physiol Lung Cell Mol Physiol 277: L282-L291, 1999.
26. Liu Y, Guyton KZ, Gorospe M, Xu Q, Lee JC, and Holbrook NL. Differential activation of ERK, JNK/SAPK and p38/ CSBP/RK MAP kinase family members during the cellular response to arsenite. Free Radic Biol Med 21: 771-781, 1996.
27. Menè P, Pugliese F, and Cinotti GA. Serotonin and the glomerular mesangium. Mechanisms of intracellular signaling. Hypertension 17: 151-160, 1991.
28. 2A receptor. Am J Physiol Renal Fluid Electrolyte Physiol 268: F122-F127, 1995.
29. Packer L, Witt EH, and Tritschler HJ. α-Lipoic acid as a biological antioxidant. Free Radic Biol Med 19: 227-250, 1995.
30. Paul RV, Wackym PS, and Budisavljevic M. Destabilization of natriuretic peptide C-receptor mRNA by phorbol myristate acetate. J Am Soc Nephrol 9: 26-32, 1998.
31. Pick E and Mizel D. Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader. J Immunol Methods 46: 211-226, 1981.
32. Rajagopalan S, Kurz S, Munzel T, Tarpey M, Freeman BA, Griendling KK, and Harrison DR. ANG II-mediated hypertension in the rat increases vascular superoxide production via membrane-bound NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. J Clin Invest 97: 1916-1923, 1996.
33. 2 in cultured endothelial cells. Arch Biochem Biophys 302: 348-355, 1993.
34. Satriano J and Schlondorff D. Activation and attenuation of transcription factor NF-κB in mouse glomerular mesangial cells in response to TNF-α, immunoglobulin G, and cAMP. J Clin Invest 94: 1629-1636, 1994.
35. Sen CK and Packer L. Antioxidant and redox regulation of gene transcription. FASEB J 10: 709-720, 1996.
36. Sole MJ, Madapallimattam A, and Baines AD. An active pathway for serotonin synthesis by renal proximal tubules. Kidney Int 29: 689-694, 1986.
37. Spurney RF, Onorato JJ, Albers FJ, and Coffman TM. Thromboxane binding and signal transduction in rat glomerular mesangial cells. Am J Physiol Renal Fluid Electrolyte Physiol 264: F292-F299, 1993.
38. Stier TC Jr and Itskovitz HD. Formation of serotonin by rat kidneys in vivo. Proc Soc Exp Biol Med 180: 550-557, 1985.
39. 2 for platelet-derived growth factor signal transduction. Science 270: 296-299, 1995.
40. Takuwa N, Ganz M, Takuwa Y, Starzl RB, and Rasmussen H. Studies of the mitogenic effect of serotonin in rat renal mesangial cells. Am J Physiol Renal Fluid Electrolyte Physiol 257: F431-F439, 1989.
41. Ushio-Fukai M, Alexander RW, Akers M, and Griendling KK. p38 Mitogen-activated protein kinase is a critical component of the redox-sensitive signaling pathways activated by angiotensin II. J Biol Chem 273: 15022-15029, 1998.
42. Van Biesen T, Luttrell LM, Hawes BJ, and Lefkowitz RJ. Mitogenic signaling via G protein-coupled receptors. Endocr Rev 17: 698-714, 1996.
43. Wilmer WA, Tan LC, Dickerson JA, Danne M, and Rovin BH. Interleukin-1β induction of mitogen-activated protein kinases in human mesangial cells. Role of oxidation. J Biol Chem 272: 10877-10881, 1997.