Serotonin 5-HT(2A) receptor induces TGF-β1 expression in mesangial cells via ERK: Proliferative and fibrotic signals

American Journal of Physiology - Renal Physiology

Volumn 276, Issue 6 45-6, 1999, Pages

  Grewal, Jasjit S ^a   Mukhin, Yurii V ^a   Garnovskaya, Maria N ^a   Raymond, John R ^a   Greene, Eddie L ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Fibrosis; Mesangial cell; Proliferation; Serotonin; Transforming growth factor

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; SEROTONIN 2A RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; BORDETELLA VIRULENCE FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SEROTONIN RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FIBROGENESIS; KIDNEY FIBROSIS; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL DIVISION; CYTOLOGY; DRUG EFFECT; FIBROSIS; GENETICS; MESANGIUM; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; FIBROSIS; GLOMERULAR MESANGIUM; GTP-BINDING PROTEINS; MALE; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NADPH OXIDASE; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, SEROTONIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; VIRULENCE FACTORS, BORDETELLA;

EID: 0033143762     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1999.276.6.f922     Document Type: Article

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