Quantitative analysis of the immunosuppressant CP-690,550 in whole blood by column-switching high-performance liquid chromatography and mass spectrometry detection

Therapeutic Drug Monitoring

Volumn 27, Issue 5, 2005, Pages 608-616

  Paniagua, Ricardo ^a   Campbell, Andrew ^a   Changelian, Paul S ^b   Reitz, Bruce A ^a   Prakash, Chandra ^b   Borie, Dominic C ^a,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PFIZER INC   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Immunosuppression; JAK STAT; Liquid chromatography; Mass spectrometry; Transplantation

Indexed keywords

4 [N [1 (2 CYANO 1 OXOETHYL) 4 METHYL 3 PIPERIDINYL] N METHYLAMINO]PYRROLO[2,3 D]PYRIMIDINE; IMMUNOSUPPRESSIVE AGENT; JANUS KINASE 3 INHIBITOR; PF 270308; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; COLUMN SWITCHING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; MACACA; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; VALIDATION PROCESS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG MONITORING; IMMUNOSUPPRESSIVE AGENTS; JANUS KINASE 3; MACACA FASCICULARIS; MALE; PROTEIN-TYROSINE KINASES; PYRIMIDINES; PYRROLES; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 17444432050     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ftd.0000170030.13702.04     Document Type: Article

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