Expression of functional hexahistidine-tagged ricin B in tobacco

Plant Cell Reports

Volumn 24, Issue 1, 2005, Pages 15-24

  Reed, Deborah G ^a   Nopo Olazabal, Luis H ^a   Funk, Vanessa ^a   Woffenden, Bonnie J ^a   Reidy, Michael J ^a   Dolan, Maureen C ^a   Cramer, Carole L ^a   Medina Bolivar, Fabricio ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Histidine tagged proteins; Mucosal delivery; Plant glycosylation; Plant based vaccines; Ricin B

Indexed keywords

ANTIBODIES; IMMUNOLOGY; MASS SPECTROMETRY; PLANTS (BOTANY); PROTEINS; PURIFICATION; TOXIC MATERIALS;

ASIALOFETUIN; GLYCOSYLATED PRODUCTS; IMMUNOBLOTTING; RICIN B;

TOBACCO;

HIS HIS HIS HIS HIS HIS; HIS-HIS-HIS-HIS-HIS-HIS; HISTIDINE; OLIGOPEPTIDE; RECOMBINANT PROTEIN; RICIN;

ARTICLE; BIOSYNTHESIS; CHEMISTRY; GENE EXPRESSION; GENETICS; METABOLISM; PHYSIOLOGY; TOBACCO; TRANSGENIC PLANT;

GENE EXPRESSION; HISTIDINE; OLIGOPEPTIDES; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; RICIN; TOBACCO;

ANTIBODIES; GALACTOSE; LACTOSE; MASS SPECTRA; PLANTS; PROTEINS; PURIFICATION; TOBACCO;

NICOTIANA TABACUM; TABACUM;

EID: 17444427747     PISSN: 07217714     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00299-004-0901-0     Document Type: Article

References (38)

1. Ausubel A, Brent R, Kingston R, Moore D, Seidman J, Smith J, Struhl K (2002) Current protocols in molecular biology. Wiley, New York
2. Bardor M, Faye L, Lerouge P (1999) Analysis of the N-glycosylation of recombinant glycoproteins produced in transgenic plants. Trends Plant Sci 4:376-380
3. Becker D (1990) Binary vectors which allow the exchange of plant selectable markers and reporter genes. Nucleic Acid Res 18:203-210
4. Butterworth AJ, Lord JM (1983) Ricin and Ricinus communis agglutinin subunits are all derived from a single-size polypeptide precursor. Eur J Biochem 137:57-65
5. Chang M-S, Russell D, Uhr J, Vitetta E (1987) Cloning and expression of recombinant, functional ricin B chain. Proc Natl Acad Sci USA 84:5640-5644
6. Di Cola A, Frigerio L, Lord JM, Ceriotti A, Roberts LM (2001) Ricin A chain without its partner B chain is degraded after retrotranslocation from the endoplasmic reticulum to the cytosol in plant cells. Proc Natl Acad Sci USA 98:14726-14731
7. Faye L, Gomord V, Fitchette-Laine AC, Chrispeels MJ (1993) Affinity purification of antibodies specific for Asn-linked glycans containing alpha 1→3 fucose or beta 1→2 xylose. Anal Biochem 209:104-108
8. Feinberg H, Mitchell D, Drickamer K, Weis W (2001) Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR. Science 294:2163-2166
9. Ferrini J, Martin M, Taupiac M, Beaumelle B (1995) Expression of functional ricin B chain using the baculovirus system. Eur J Biochem 233:772-777
10. Frankel A, Fu T, Burbage C, Tagge E, Harris B, Vesely J, Willingham MC (1997) Lectin-deficient ricin toxin intoxicates cells bearing the D-mannose receptor. Carbohydr Res 300:251-258
11. Frigerio L, Vitale A, Lord J, Ceriotti A, Roberts L (1998) Free ricin A chain, proricin, and native toxin have different cellular fates when expressed in tobacco protoplasts. J Biol Chem 273:14194-14199
12. Frigerio L, Jolliffe N, Di Cola A, Filipe D, Paris N, Neuhaus J, Lord J, Ceriotti A, Roberts L (2001) The internal propeptide of the ricin precursor carries a sequence-specific determinant for vacuolar sorting. Plant Physiol 126:167-175
13. Holsters M, de Waele D, Depicker A, Messens E, Van Montangu M, Schell J (1978) Transfection and transformation of A. tumefaciens. Mol Gen Genet 163:181-187
14. Jepson M, Clark M, Hirst B (2004) M-cell targeting by lectins: a strategy for mucosal vaccination and drug delivery. Adv Drug Deliv Rev 56:511-525
15. Kimura Y, Hase S, Kobayashi Y, Kyogoku Y, Ikenaka T, Funatsu G (1988) Structures of sugar chains of ricin D. J Biochem 103:944-949
16. Lavelle EC, Grant G, Pusztai A, Pfuller U, O'Hagan DT (2001) The identification of plant lectins with mucosal adjuvant activity. Immunology 102:77-86
17. Lavelle EC, Grant G, Pusztai A, Pfuller U, Leavy O, McNeela E, Mills K, O'Hagan D (2002) Mistletoe lectins enhance immune responses to intranasally co-administered herpes simplex virus glycoprotein D2. Immunology 107:268-274
18. Lerouge P, Cabanes-Macheteau M, Rayon C, Fischette-Laine AC, Gomord V, Faye L (1998) N-glycoprotein biosynthesis in plants: recent developments and future trends. Plant Mol Biol 38:31-48
19. Lord JM, Roberts LM (1998) Toxin entry: retrograde transport through the secretory pathway. J Cell Biol 140:733-736
20. Lord JM, Jolliffe NA, Marsden CJ, Pateman CS, Smith DC, Spooner RA, Watson PD, Roberts LM (2003) Ricin, Mechanisms of cytotoxicity. Toxicol Rev 22:53-64
21. Magnusson S, Kjeken R, Berg T (1993) Characterization of two distinct pathways of endocytosis of ricin by rat liver endothelial cells. Exp Cell Res 205:118-125
22. Martin SE, Shabanowitz J, Hunt DF, Marto JA (2000) Subfemtomole MS and MS/MS peptide sequence analysis using nano-HPLC micro-ESI fourier transform ion cyclotron resonance mass spectrometry. Anal Chem 72:4266-4274
23. Medina-Bolivar F, Wright R, Funk V, Sentz D, Barroso L, Wilkins T, Petri W Jr, Cramer C (2003) A non-toxic lectin for antigen delivery of plant-based mucosal vaccines. Vaccine 21:997-1005
24. Medina-Bolivar F, Cramer C (2004) Production of recombinant proteins in hairy roots cultured in plastic sleeve bioreactors. In: Balbas P, Lorence A (eds) Recombinant gene expression: reviews and protocols. Humana Press, Totowa, pp 351-363
25. Montfort W, Villafranca J, Monzingo A, Ernst S, Katzin B, Rutenber E, Xuong N, Hamlin R, Robertus J (1987) The three-dimensional structure of ricin at 2.8 A. J Biol Chem 262:5398-5403
26. Olsnes S, Kozlov JV (2001) Ricin. Toxicon 39:1723-1728
27. Richardson P, Gilmartin P, Colman A, Roberts L, Lord J (1988a) Expression of functional ricin B chain in Xenopus oocytes. Biotechnology 6:565-570
28. Richardson P, Roberts L, Gould J, Lord J (1988b) The expression of functional ricin B-chain in Saccharomyces cerevisiae. Biochim Biophys Acta 950:385-394
29. Richardson P, Hussain K, Woodland H, Lord J, Roberts L (1991) The effects of N-glycosylation on the lectin activity of recombinant ricin B chain. Carbohydr Res 213:19-25
30. Roberts L, Lord J (2004) Ribosome-inactivating proteins: entry into mammalian cells and intracellular routing. Mini Rev Med Chem 4:505-512
31. Sambrook J, Fritsch E, Maniatis T (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Plainview
32. Sehnke P, Pedrosa L, Paul A, Frankel A, Ferl R (1994) Expression of active, processed ricin in transgenic tobacco. J Biol Chem 269:22473-22476
33. Shevchenko A, Wilm M, Vorm O, Mann M (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68:850-858
34. Simmons BM, Stahl PD, Russell JH (1986) Mannose receptor-mediated uptake of ricin toxin and ricin A chain by macrophages. J Biol Chem 261:7912-7920
35. Smith D, Gallimore A, Jones E, Roberts B, Lord J, Deeks E, Cerundolo V, Roberts L (2002) Exogenous peptides delivered by ricin require processing by signal peptidase for transporter associated with antigen processing-independent MHC class I-restricted presentation. J Immunol 169:99-107
36. Spooner R, Watson P, Marsden C, Smith D, Moore K, Cook J, Lord J, Roberts L (2004) Protein disulfide isomerase reduces ricin to it's a and B chains in the endoplasmic reticulum. Biochem J 383:285-293
37. Tonevitsky A, Agapov I, Bushueva T, Toptygin A, Shamshiev A, Sweeney E, Palmer R, Frankel A (1994) Stability and biological activity of native and recombinant ricin toxin B-chain. Protein Pept Lett 1:195-201
38. Van Kooyk Y, Geijtenbeek T (2002) A novel adhesion pathway that regulates dendritic cell trafficking and T cell interactions. Immunol Rev 186:47-46