Impairment of redox state and dopamine level induced by α-synuclein aggregation and the prevention effect of hsp70

Biochemical and Biophysical Research Communications

Volumn 331, Issue 1, 2005, Pages 278-284

  Yu, FuRong ^a   Xu, HuaTai ^c   Zhuo, Ming ^a   Sun, LanYing ^a   Dong, AiWen ^a   Liu, XinYuan ^a,b  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b ZHEJIANG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Dopamine; Lewy body; Neurodegeneration; Oxidative stress; Parkinson's disease; SK N SH cell line

Indexed keywords

ALPHA SYNUCLEIN; DOPAMINE; HEAT SHOCK PROTEIN 70;

APOPTOSIS; ARTICLE; CELL DEATH; CELL LEVEL; CELL LOSS; CELL POPULATION; CONTROLLED STUDY; CYTOPLASM; DRUG EFFECT; EXAMINATION; GENE CONTROL; GENE OVEREXPRESSION; HOMEOSTASIS; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NERVE CELL; NERVE DEGENERATION; NEUROPROTECTION; OXIDATION REDUCTION REACTION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN INDUCTION;

EID: 17444412633     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.03.148     Document Type: Article

References (15)

1. P.K. Auluck, H. Chan, J.Q. Trojanowski, V. Lee, and N.M. Bonini Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's Disease Science 295 2002 865 868.
2. N.M. Bonini Chaperoning brain degeneration Pro. Natl. Acad. Sci. USA 99 Suppl. 4 2002 16407 16411
3. J.C. De la Torre An improved approach to histofluorescence using the SPG method for tissue monoamines J. Neurosci. Methods 3 1980 1 5
4. M.B. Feany, and W.W. Bender A Drosophila model of Parkinson's disease Nature 404 2000 394 398
5. M. Goedert Alpha-synuclein and neurodegenerative disease Nat. Rev. Neurosci. 2 7 2001 492 501
6. C.S. Lee, H. Sauer, and A. Bjorklund A dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by intrastriatal 6-hydroxydopamine in the rat Neuroscience 72 1996 641 653
7. E. Masliah, E. Rockenstein, I. Veibergs, M. Mallory, M. Hashimoto, A. Takeda, Y. Sagara, A. Sisk, and L. Mucke Dopaminergic loss and inclusion body formation in α-synuclein mice: implications for neurodegenerative disorders Science 287 2000 1265 1268
8. L. Narhi, S.J. Wood, S. Steavenson, Y. Jiang, G.M. Wu, D. Anafi, S.A. Kaufman, F. Martin, K. Sitney, P. Denis, J.C. Louis, J. Wypych, A.L. Biere, and M. Citron Both familial Parkinson's disease mutations accelerate α-synuclein aggregation J. Biol. Chem. 274 14 1999 9843 9846
9. R.G. Perez, J.C. Waymire, E. Lin, J.J. Liu, F. Guo, and M.J. Zigmond A role for the α-synuclein in the regulation of dopamine biosynthesis J. Neurosci. 22 8 2002 3090 3099
10. T. Sasada, S. Iwata, N. Sato, Y. Kitaoka, K. Hirota, K. Nakamura, A. Nishiyama, Y. Taniguchi, A. Takabayashi, and J. Yodoi Redox control of resistance to cis-diamminedichloroplatinum(II) (CDDP): protective effect of human thioredoxin against ADDP-induced cytotoxicity J. Clin. Invest. 97 10 1996 2268 2276
11. H. Sauer, and W.H. Oertel Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat Neuroscience 59 1994 401 415
12. J.M. Warrick, H.Y. Chan, G.L. Gray-Board, Y. Chai, H.L. Paulson, and N.M. Bonini Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone hsp70 Nat. Genet. 23 4 1999 425 428
13. A.B. Zubrow, M. Delivoria-Papadopoulos, Q.M. Ashraf, J.R. Ballesteros, K.I. Fritz, and O.P. Mishra Nitric oxide-mediated expression of Bax protein and DNA fragmentation during hypoxia in neuronal nuclei from newborn piglets Brain Res. 954 2002 60 67
14. C. Alves Da Costa, E. Paitel, B. Vincent, and F. Checler Alpha-synuclein lowers p53 dependent apoptotic response of neuronal cells J. Biol. Chem. 277 52 2002 50980 50984
15. M. Hashimoto, L.J. Hsu, Y. Xia, A. Takeda, A. Sisk, M. Sundsmo, and E. Masliah Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro Neuroreport 10 4 1999 717 721