메뉴 건너뛰기




Volumn 54, Issue 5, 2005, Pages 431-445

Epithelial tight junction proteins as potential antibody targets for pancarcinoma therapy

Author keywords

Antibody; Carcinoma; Claudin; Gene expression; Therapeutic target; Tight junction

Indexed keywords

ANTIBODY; CLAUDIN; CLAUDIN 1; CLAUDIN 3; CLAUDIN 4; CLAUDIN 7; CLAUDIN 8; IMMUNOGLOBULIN G; MESSENGER RNA; POLYCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 17444402091     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-004-0613-x     Document Type: Article
Times cited : (55)

References (65)
  • 3
    • 0036468297 scopus 로고    scopus 로고
    • Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines
    • Arlt A, Vorndamm J, Muerkoster S, Yu H, Schmidt WE, Folsch UR, Schafer H (2002) Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines. Cancer Res 62:910-916
    • (2002) Cancer Res , vol.62 , pp. 910-916
    • Arlt, A.1    Vorndamm, J.2    Muerkoster, S.3    Yu, H.4    Schmidt, W.E.5    Folsch, U.R.6    Schafer, H.7
  • 5
    • 0032962333 scopus 로고    scopus 로고
    • Tumor-antigen heterogeneity of disseminated breast cancer cells: Implications for immunotherapy of minimal residual disease
    • Braun S, Hepp F, Sommer HL, Pantel K (1999) Tumor-antigen heterogeneity of disseminated breast cancer cells: implications for immunotherapy of minimal residual disease. Int J Cancer 84:1-5
    • (1999) Int J Cancer , vol.84 , pp. 1-5
    • Braun, S.1    Hepp, F.2    Sommer, H.L.3    Pantel, K.4
  • 9
    • 0036644617 scopus 로고    scopus 로고
    • Assembly of the immunological synapse for T cells and NK cells
    • Davis DM (2002) Assembly of the immunological synapse for T cells and NK cells. Trends Immunol 23:356-363
    • (2002) Trends Immunol , vol.23 , pp. 356-363
    • Davis, D.M.1
  • 10
    • 0037478897 scopus 로고    scopus 로고
    • A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity
    • Di Paolo C, Willuda J, Kubetzko S, Lauffer I, Tschudi D, Waibel R, Pluckthun A, Stahel RA, Zangemeister-Wittke U (2003) A recombinant immunotoxin derived from a humanized epithelial cell adhesion molecule-specific single-chain antibody fragment has potent and selective antitumor activity. Clin Cancer Res 9:2837-2848
    • (2003) Clin Cancer Res , vol.9 , pp. 2837-2848
    • Di Paolo, C.1    Willuda, J.2    Kubetzko, S.3    Lauffer, I.4    Tschudi, D.5    Waibel, R.6    Pluckthun, A.7    Stahel, R.A.8    Zangemeister-Wittke, U.9
  • 11
    • 0034617463 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein
    • Fujita K, Katahira J, Horiguchi Y, Sonoda N, Furuse M, Tsukita S (2000) Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein. FEBS Lett 476:258-261
    • (2000) FEBS Lett , vol.476 , pp. 258-261
    • Fujita, K.1    Katahira, J.2    Horiguchi, Y.3    Sonoda, N.4    Furuse, M.5    Tsukita, S.6
  • 12
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S (1998) Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141:1539-1550
    • (1998) J Cell Biol , vol.141 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.4    Tsukita, S.5
  • 13
    • 0032547833 scopus 로고    scopus 로고
    • A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts
    • Furuse M, Sasaki H, Fujimoto K, Tsukita S (1998) A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol 143:391-401
    • (1998) J Cell Biol , vol.143 , pp. 391-401
    • Furuse, M.1    Sasaki, H.2    Fujimoto, K.3    Tsukita, S.4
  • 14
    • 0033571047 scopus 로고    scopus 로고
    • Manner of interaction of heterogeneous claudin species within and between tight junction strands
    • Furuse M, Sasaki H, Tsukita S (1999) Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol 147:891-903
    • (1999) J Cell Biol , vol.147 , pp. 891-903
    • Furuse, M.1    Sasaki, H.2    Tsukita, S.3
  • 15
    • 0034627152 scopus 로고    scopus 로고
    • EpCAM overexpression in breast cancer as a predictor of survival
    • Gastl G, Spizzo G, Obrist P, Dunser M, Mikuz G (2000) EpCAM overexpression in breast cancer as a predictor of survival. Lancet 356:1981-1982
    • (2000) Lancet , vol.356 , pp. 1981-1982
    • Gastl, G.1    Spizzo, G.2    Obrist, P.3    Dunser, M.4    Mikuz, G.5
  • 16
    • 0032005642 scopus 로고    scopus 로고
    • Levels of expression of CD52 in normal and leukemic B and T cells: Correlation with in vivo therapeutic responses to Campath-1H
    • Ginaldi L, De Martinis M, Matutes E, Farahat N, Morilla R, Dyer MJ, Catovsky D (1998) Levels of expression of CD52 in normal and leukemic B and T cells: correlation with in vivo therapeutic responses to Campath-1H. Leuk Res 22:185-191
    • (1998) Leuk Res , vol.22 , pp. 185-191
    • Ginaldi, L.1    De Martinis, M.2    Matutes, E.3    Farahat, N.4    Morilla, R.5    Dyer, M.J.6    Catovsky, D.7
  • 17
    • 0032895235 scopus 로고    scopus 로고
    • Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
    • Goldenberg MM (1999) Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin Ther 21:309-318
    • (1999) Clin Ther , vol.21 , pp. 309-318
    • Goldenberg, M.M.1
  • 18
    • 0024503472 scopus 로고
    • Establishment of tight junctions between cells from different animal species and different sealing capacities
    • Gonzalez-Mariscal L, Chavez de Ramirez B, Lazaro A, Cereijido M (1989) Establishment of tight junctions between cells from different animal species and different sealing capacities. J Membr Biol 107:43-56
    • (1989) J Membr Biol , vol.107 , pp. 43-56
    • Gonzalez-Mariscal, L.1    De Chavez Ramirez, B.2    Lazaro, A.3    Cereijido, M.4
  • 19
    • 0022480614 scopus 로고
    • The epithelial cell surface antigen 17-1A, a target for antibody-mediated tumor therapy: Its biochemical nature, tissue distribution and recognition by different monoclonal antibodies
    • Gottlinger HG, Funke I, Johnson JP, Gokel JM, Riethmuller G (1986) The epithelial cell surface antigen 17-1A, a target for antibody-mediated tumor therapy: its biochemical nature, tissue distribution and recognition by different monoclonal antibodies. Int J Cancer 38:47-53
    • (1986) Int J Cancer , vol.38 , pp. 47-53
    • Gottlinger, H.G.1    Funke, I.2    Johnson, J.P.3    Gokel, J.M.4    Riethmuller, G.5
  • 20
    • 0036175938 scopus 로고    scopus 로고
    • Rituximab as first-line and maintenance therapy for patients with indolent non-Hodgkin's lymphoma: Interim follow-up of a multicenter phase II trial
    • Hainsworth JD (2002) Rituximab as first-line and maintenance therapy for patients with indolent non-Hodgkin's lymphoma: interim follow-up of a multicenter phase II trial. Semin Oncol 29:25-29
    • (2002) Semin Oncol , vol.29 , pp. 25-29
    • Hainsworth, J.D.1
  • 21
    • 0036197421 scopus 로고    scopus 로고
    • Expression and targeting of the tight junction protein CLDN1 in CLDN1-negative human breast tumor cells
    • Hoevel T, Macek R, Mundigl O, Swisshelm K, Kubbies M (2002) Expression and targeting of the tight junction protein CLDN1 in CLDN1-negative human breast tumor cells. J Cell Physiol 191:60-68
    • (2002) J Cell Physiol , vol.191 , pp. 60-68
    • Hoevel, T.1    Macek, R.2    Mundigl, O.3    Swisshelm, K.4    Kubbies, M.5
  • 23
    • 0022006660 scopus 로고
    • Antibody density on rat red cells determines the rate of activation of the complement component C1
    • Hughes-Jones NC, Gorick BD, Howard JC, Feinstein A (1985) Antibody density on rat red cells determines the rate of activation of the complement component C1. Eur J Immunol 15:976-980
    • (1985) Eur J Immunol , vol.15 , pp. 976-980
    • Hughes-Jones, N.C.1    Gorick, B.D.2    Howard, J.C.3    Feinstein, A.4
  • 24
    • 0030716491 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo
    • Katahira J, Sugiyama H, Inoue N, Horiguchi Y, Matsuda M, Sugimoto N (1997) Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo. J Biol Chem 272:26652-26658
    • (1997) J Biol Chem , vol.272 , pp. 26652-26658
    • Katahira, J.1    Sugiyama, H.2    Inoue, N.3    Horiguchi, Y.4    Matsuda, M.5    Sugimoto, N.6
  • 27
    • 0036208599 scopus 로고    scopus 로고
    • Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments
    • Kiuchi-Saishin Y, Gotoh S, Furuse M, Takasuga A, Tano Y, Tsukita S (2002) Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. J Am Soc Nephrol 13:875-886
    • (2002) J Am Soc Nephrol , vol.13 , pp. 875-886
    • Kiuchi-Saishin, Y.1    Gotoh, S.2    Furuse, M.3    Takasuga, A.4    Tano, Y.5    Tsukita, S.6
  • 28
    • 0035910270 scopus 로고    scopus 로고
    • Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
    • Krogh A, Larsson B, von Heijne G, Sonnhammer EL (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J Mol Biol 305:567-580
    • (2001) J Mol Biol , vol.305 , pp. 567-580
    • Krogh, A.1    Larsson, B.2    Von Heijne, G.3    Sonnhammer, E.L.4
  • 29
    • 0033598188 scopus 로고    scopus 로고
    • Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions
    • Kubota K, Furuse M, Sasaki H, Sonoda N, Fujita K, Nagafuchi A, Tsukita S (1999) Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions. Curr Biol 9:1035-1038
    • (1999) Curr Biol , vol.9 , pp. 1035-1038
    • Kubota, K.1    Furuse, M.2    Sasaki, H.3    Sonoda, N.4    Fujita, K.5    Nagafuchi, A.6    Tsukita, S.7
  • 33
    • 0035503028 scopus 로고    scopus 로고
    • Expression of Clostridium perfringens enterotoxin receptors claudin-3 and claudin-4 in prostate cancer epithelium
    • Long H, Crean CD, Lee WH, Cummings OW, Gabig TG (2001) Expression of Clostridium perfringens enterotoxin receptors claudin-3 and claudin-4 in prostate cancer epithelium. Cancer Res 61:7878-7881
    • (2001) Cancer Res , vol.61 , pp. 7878-7881
    • Long, H.1    Crean, C.D.2    Lee, W.H.3    Cummings, O.W.4    Gabig, T.G.5
  • 34
    • 0029148633 scopus 로고
    • A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
    • Mack M, Riethmuller G, Kufer P (1995) A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity. Proc Natl Acad Sci U S A 92:7021-7025
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7021-7025
    • Mack, M.1    Riethmuller, G.2    Kufer, P.3
  • 35
    • 0031943571 scopus 로고    scopus 로고
    • Regulation of the movement of solutes across tight junctions
    • Madara JL (1998) Regulation of the movement of solutes across tight junctions. Annu Rev Physiol 60:143-159
    • (1998) Annu Rev Physiol , vol.60 , pp. 143-159
    • Madara, J.L.1
  • 36
    • 0031727426 scopus 로고    scopus 로고
    • Occludin and the functions of tight junctions
    • Matter K, Balda MS (1999) Occludin and the functions of tight junctions. Int Rev Cytol 186:117-146
    • (1999) Int Rev Cytol , vol.186 , pp. 117-146
    • Matter, K.1    Balda, M.S.2
  • 41
    • 0033851771 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: Lessons from mutant animals and proteins
    • Mitic LL, Van Itallie CM, Anderson JM (2000) Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins. Am J Physiol Gastrointest Liver Physiol 279:G250-G254
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Mitic, L.L.1    Van Itallie, C.M.2    Anderson, J.M.3
  • 42
    • 0033582334 scopus 로고    scopus 로고
    • Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
    • Morita K, Furuse M, Fujimoto K, Tsukita S (1999) Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci U S A 96:511-516
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 511-516
    • Morita, K.1    Furuse, M.2    Fujimoto, K.3    Tsukita, S.4
  • 43
    • 0033523758 scopus 로고    scopus 로고
    • Endothelial claudin: Claudin-5/TMVCF constitutes tight junction strands in endothelial cells
    • Morita K, Sasaki H, Furuse M, Tsukita S (1999) Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol 147:185-194
    • (1999) J Cell Biol , vol.147 , pp. 185-194
    • Morita, K.1    Sasaki, H.2    Furuse, M.3    Tsukita, S.4
  • 45
    • 0031673786 scopus 로고    scopus 로고
    • Immunohistochemical localization of epithelial glycoprotein EGP-2 and carcinoembryonic antigen in normal colonic mucosa and colorectal tumors
    • Ogura E, Senzaki H, Yoshizawa K, Hioki K, Tsubura A (1998) Immunohistochemical localization of epithelial glycoprotein EGP-2 and carcinoembryonic antigen in normal colonic mucosa and colorectal tumors. Anticancer Res 18:3669-3675
    • (1998) Anticancer Res , vol.18 , pp. 3669-3675
    • Ogura, E.1    Senzaki, H.2    Yoshizawa, K.3    Hioki, K.4    Tsubura, A.5
  • 46
    • 0029867674 scopus 로고    scopus 로고
    • Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases
    • Pantel K, Izbicki J, Passlick B, Angstwurm M, Haussinger K, Thetter O, Riethmuller G (1996) Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. Lancet 347:649-653
    • (1996) Lancet , vol.347 , pp. 649-653
    • Pantel, K.1    Izbicki, J.2    Passlick, B.3    Angstwurm, M.4    Haussinger, K.5    Thetter, O.6    Riethmuller, G.7
  • 49
    • 0035129369 scopus 로고    scopus 로고
    • Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut
    • Rahner C, Mitic LL, Anderson JM (2001) Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut. Gastroenterology 120:411-422
    • (2001) Gastroenterology , vol.120 , pp. 411-422
    • Rahner, C.1    Mitic, L.L.2    Anderson, J.M.3
  • 50
    • 0033166662 scopus 로고    scopus 로고
    • Hunting down the seminal cells of clinical metastases
    • Riethmuller G, Klein CA, Pantel K (1999) Hunting down the seminal cells of clinical metastases. Immunol Today 20:294-296
    • (1999) Immunol Today , vol.20 , pp. 294-296
    • Riethmuller, G.1    Klein, C.A.2    Pantel, K.3
  • 51
    • 0034775122 scopus 로고    scopus 로고
    • Variability in B-cell antigen expression: Implications for the treatment of B-cell lymphomas and leukemias with monoclonal antibodies
    • Rossmann ED, Lundin J, Lenkei R, Mellstedt H, Osterborg A (2001) Variability in B-cell antigen expression: implications for the treatment of B-cell lymphomas and leukemias with monoclonal antibodies. Hematol J 2:300-306
    • (2001) Hematol J , vol.2 , pp. 300-306
    • Rossmann, E.D.1    Lundin, J.2    Lenkei, R.3    Mellstedt, H.4    Osterborg, A.5
  • 53
    • 0034812866 scopus 로고    scopus 로고
    • Clinical experience with edrecolomab: A monoclonal antibody therapy for colorectal carcinoma
    • Schwartzberg LS (2001) Clinical experience with edrecolomab: a monoclonal antibody therapy for colorectal carcinoma. Crit Rev Oncol Hematol 40:17-24
    • (2001) Crit Rev Oncol Hematol , vol.40 , pp. 17-24
    • Schwartzberg, L.S.1
  • 55
    • 0033523773 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier
    • Sonoda N, Furuse M, Sasaki H, Yonemura S, Katahira J, Horiguchi Y, Tsukita S (1999) Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: evidence for direct involvement of claudins in tight junction barrier. J Cell Biol 147:195-204
    • (1999) J Cell Biol , vol.147 , pp. 195-204
    • Sonoda, N.1    Furuse, M.2    Sasaki, H.3    Yonemura, S.4    Katahira, J.5    Horiguchi, Y.6    Tsukita, S.7
  • 59
    • 0034599992 scopus 로고    scopus 로고
    • Pores in the wall: Claudins constitute tight junction strands containing aqueous pores
    • Tsukita S, Furuse M (2000) Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol 149:13-16
    • (2000) J Cell Biol , vol.149 , pp. 13-16
    • Tsukita, S.1    Furuse, M.2
  • 60
    • 0036773738 scopus 로고    scopus 로고
    • Claudin-based barrier in simple and stratified cellular sheets
    • Tsukita S, Furuse M (2002) Claudin-based barrier in simple and stratified cellular sheets. Curr Opin Cell Biol 14:531-536
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 531-536
    • Tsukita, S.1    Furuse, M.2
  • 61
    • 0032842426 scopus 로고    scopus 로고
    • Structural and signalling molecules come together at tight junctions
    • Tsukita S, Furuse M, Itoh M (1999) Structural and signalling molecules come together at tight junctions. Curr Opin Cell Biol 11:628-633
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 628-633
    • Tsukita, S.1    Furuse, M.2    Itoh, M.3
  • 63
    • 0034947347 scopus 로고    scopus 로고
    • Disseminated cytokeratin positive tumor cells in the bone marrow of patients with prostate cancer: Detection and prognostic value
    • Weckermann D, Muller P, Wawroschek F, Harzmann R, Riethmuller G, Schlimok G (2001) Disseminated cytokeratin positive tumor cells in the bone marrow of patients with prostate cancer: detection and prognostic value. J Urol 166:699-703
    • (2001) J Urol , vol.166 , pp. 699-703
    • Weckermann, D.1    Muller, P.2    Wawroschek, F.3    Harzmann, R.4    Riethmuller, G.5    Schlimok, G.6
  • 65
    • 0031912919 scopus 로고    scopus 로고
    • Expression of potential target antigens for immunotherapy on primary and metastatic prostate cancers
    • Zhang S, Zhang HS, Reuter VE, Slovin SF, Scher HI, Livingston PO (1998) Expression of potential target antigens for immunotherapy on primary and metastatic prostate cancers. Clin Cancer Res 4:295-302
    • (1998) Clin Cancer Res , vol.4 , pp. 295-302
    • Zhang, S.1    Zhang, H.S.2    Reuter, V.E.3    Slovin, S.F.4    Scher, H.I.5    Livingston, P.O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.