Optimisation of pyrogen testing in parenterals according to different pharmacopoeias by probabilistic modelling

Journal of Endotoxin Research

Volumn 11, Issue 1, 2005, Pages 25-31

  Hoffmann, Sebastian ^a   Lüderitz Püchel, Ursula ^b   Montag, Thomas ^b   Hartung, Thomas ^a  

^a JOINT RESEARCH CENTRE   (Italy)

^b PAUL EHRLICH INSTITUT   (Germany)

Author keywords

Animal model; Animal welfare; Pharmacopoeias; Pyrogens; Statistical model

Indexed keywords

ENDOTOXIN; PYROGEN;

ALGORITHM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL WELFARE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DATA ANALYSIS; EXPERIMENTAL DESIGN; FEVER; LINEAR REGRESSION ANALYSIS; MEDICAL LITERATURE; NONHUMAN; PROBABILITY; PROCESS OPTIMIZATION; RABBIT; REGULATORY MECHANISM; TOXICITY TESTING;

ALGORITHMS; ANIMAL WELFARE; ANIMALS; EUROPE; FEVER; JAPAN; MODELS, STATISTICAL; PHARMACOPOEIAS; PYROGENS; RABBITS; UNITED STATES;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 17344362447     PISSN: 09680519     EISSN: None     Source Type: Journal    
DOI: 10.1179/096805105225006678     Document Type: Article

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