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Volumn 26, Issue 1, 2004, Pages 63-74

Excess Bcl-XL increases the intrinsic growth potential of adult CNS neurons in vitro

Author keywords

B cell lymphoma 2 XL; Bcl 2 XL; ganglion cell layer; GCL; MAPK; mitogen activated protein kinase; nerve fiber layer; NFL; ON; optic nerve; phosphoinositide 3 OH kinase; PI3K; retinal ganglion cell; RGC; SC; superior colliculus

Indexed keywords

ADENOVIRUS VECTOR; PROTEIN BCL XL; BCL2L1 PROTEIN, RAT; PROTEIN BCL 2; PROTEIN BCL X;

EID: 17144464302     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2004.01.007     Document Type: Article
Times cited : (34)

References (52)
  • 1
    • 0028310855 scopus 로고
    • Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats
    • Berkelaar M., Clarke D.B., Wang Y.C., Bray G.M., Aguayo A.J. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J. Neurosci. 14:1994;4368-4374
    • (1994) J. Neurosci. , vol.14 , pp. 4368-4374
    • Berkelaar, M.1    Clarke, D.B.2    Wang, Y.C.3    Bray, G.M.4    Aguayo, A.J.5
  • 2
    • 0342894730 scopus 로고    scopus 로고
    • The anti-apoptosis bcl-2 proto-oncogene is preferentially expressed in limbic structures of the primate brain
    • Bernier P.J., Parent A. The anti-apoptosis bcl-2 proto-oncogene is preferentially expressed in limbic structures of the primate brain. Neuroscience. 82:1998;635-640
    • (1998) Neuroscience , vol.82 , pp. 635-640
    • Bernier, P.J.1    Parent, A.2
  • 3
    • 0028559768 scopus 로고
    • An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
    • Bett A.J., Haddara W., Prevec L., Graham F.L. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc. Natl. Acad. Sci. U. S. A. 91:1994;8802-8806
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 8802-8806
    • Bett, A.J.1    Haddara, W.2    Prevec, L.3    Graham, F.L.4
  • 4
    • 0030008918 scopus 로고    scopus 로고
    • Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2
    • Bonfanti L., Strettoi E., Chierzi S., Cenni M.C., Liu X.H., Martinou J.C., Maffei L., Rabacchi S.A. Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2. J. Neurosci. 16:1996;4186-4194
    • (1996) J. Neurosci. , vol.16 , pp. 4186-4194
    • Bonfanti, L.1    Strettoi, E.2    Chierzi, S.3    Cenni, M.C.4    Liu, X.H.5    Martinou, J.C.6    Maffei, L.7    Rabacchi, S.A.8
  • 5
    • 0036663014 scopus 로고    scopus 로고
    • In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis
    • Cao G., Pei W., Ge H., Liang Q., Luo Y., Sharp F.R., Lu A., Ran R., Graham S.H., Chen J. In vivo delivery of a Bcl-xL fusion protein containing the TAT protein transduction domain protects against ischemic brain injury and neuronal apoptosis. J. Neurosci. 22:2002;5423-5431
    • (2002) J. Neurosci. , vol.22 , pp. 5423-5431
    • Cao, G.1    Pei, W.2    Ge, H.3    Liang, Q.4    Luo, Y.5    Sharp, F.R.6    Lu, A.7    Ran, R.8    Graham, S.H.9    Chen, J.10
  • 6
    • 0023967246 scopus 로고
    • Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter
    • Caroni P., Schwab M.E. Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron. 1:1988;85-96
    • (1988) Neuron , vol.1 , pp. 85-96
    • Caroni, P.1    Schwab, M.E.2
  • 7
    • 0029738162 scopus 로고    scopus 로고
    • Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice
    • Cenni M.C., Bonfanti L., Martinou J.C., Ratto G.M., Strettoi E., Maffei L. Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice. Eur. J. Neurosci. 8:1996;1735-1745
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1735-1745
    • Cenni, M.C.1    Bonfanti, L.2    Martinou, J.C.3    Ratto, G.M.4    Strettoi, E.5    Maffei, L.6
  • 8
    • 0001343810 scopus 로고    scopus 로고
    • Bcl-2 promotes regeneration of severed axons in mammalian CNS
    • Chen D.F., Schneider G.E., Martinou J.C., Tonegawa S. Bcl-2 promotes regeneration of severed axons in mammalian CNS. Nature. 385:1997;434-439
    • (1997) Nature , vol.385 , pp. 434-439
    • Chen, D.F.1    Schneider, G.E.2    Martinou, J.C.3    Tonegawa, S.4
  • 9
    • 0033216121 scopus 로고    scopus 로고
    • Optic nerve crush: Axonal responses in wild-type and bcl-2 transgenic mice
    • Chierzi S., Strettoi E., Cenni M.C., Maffei L. Optic nerve crush: axonal responses in wild-type and bcl-2 transgenic mice. J. Neurosci. 19:1999;8367-8376
    • (1999) J. Neurosci. , vol.19 , pp. 8367-8376
    • Chierzi, S.1    Strettoi, E.2    Cenni, M.C.3    Maffei, L.4
  • 10
    • 0037285301 scopus 로고    scopus 로고
    • Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons
    • Cui Q., Yip H.K., Zhao R.C., So K.F., Harvey A.R. Intraocular elevation of cyclic AMP potentiates ciliary neurotrophic factor-induced regeneration of adult rat retinal ganglion cell axons. Mol. Cell. Neurosci. 22:2003;49-61
    • (2003) Mol. Cell. Neurosci. , vol.22 , pp. 49-61
    • Cui, Q.1    Yip, H.K.2    Zhao, R.C.3    So, K.F.4    Harvey, A.R.5
  • 11
    • 0035968887 scopus 로고    scopus 로고
    • Bcl-2 is not required in retinal ganglion cells surviving optic nerve axotomy
    • Dietz G.P., Kilic E., Bähr M., Isenmann S. Bcl-2 is not required in retinal ganglion cells surviving optic nerve axotomy. NeuroReport. 12:2001;3353-3356
    • (2001) NeuroReport , vol.12 , pp. 3353-3356
    • Dietz, G.P.1    Kilic, E.2    Bähr, M.3    Isenmann, S.4
  • 12
    • 0036395238 scopus 로고    scopus 로고
    • Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction
    • Dietz G.P., Kilic E., Bähr M. Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction. Mol. Cell. Neurosci. 21:2002;29-37
    • (2002) Mol. Cell. Neurosci. , vol.21 , pp. 29-37
    • Dietz, G.P.1    Kilic, E.2    Bähr, M.3
  • 13
    • 0033180342 scopus 로고    scopus 로고
    • The glial scar and central nervous system repair
    • Fawcett J.W., Asher R.A. The glial scar and central nervous system repair. Brain Res. Bull. 49:1999;377-391
    • (1999) Brain Res. Bull. , vol.49 , pp. 377-391
    • Fawcett, J.W.1    Asher, R.A.2
  • 14
    • 0141499228 scopus 로고    scopus 로고
    • Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
    • Filbin M.T. Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat. Rev., Neurosci. 4:2003;703-713
    • (2003) Nat. Rev., Neurosci. , vol.4 , pp. 703-713
    • Filbin, M.T.1
  • 15
    • 0035905799 scopus 로고    scopus 로고
    • Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration
    • Fournier A.E., GrandPre T., Strittmatter S.M. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature. 409:2001;341-346
    • (2001) Nature , vol.409 , pp. 341-346
    • Fournier, A.E.1    Grandpre, T.2    Strittmatter, S.M.3
  • 17
    • 0031260570 scopus 로고    scopus 로고
    • Bcl-2 influences axonal growth rate in embryonic sensory neurons
    • Hilton M., Middleton G., Davies A.M. Bcl-2 influences axonal growth rate in embryonic sensory neurons. Curr. Biol. 7:1997;798-800
    • (1997) Curr. Biol. , vol.7 , pp. 798-800
    • Hilton, M.1    Middleton, G.2    Davies, A.M.3
  • 18
  • 19
    • 0028366326 scopus 로고
    • Regulation of immediate-early gene expression in rat retinal ganglion cells after axotomy and during regeneration through a peripheral nerve graft
    • Hüll M., Bähr M. Regulation of immediate-early gene expression in rat retinal ganglion cells after axotomy and during regeneration through a peripheral nerve graft. J. Neurobiol. 25:1994;92-105
    • (1994) J. Neurobiol. , vol.25 , pp. 92-105
    • Hüll, M.1    Bähr, M.2
  • 20
    • 0036616874 scopus 로고    scopus 로고
    • Bcl-2 overexpression does not enhance in vivo axonal regeneration of retinal ganglion cells after peripheral nerve transplantation in adult mice
    • Inoue T., Hosokawa M., Morigiwa K., Ohashi Y., Fukuda Y. Bcl-2 overexpression does not enhance in vivo axonal regeneration of retinal ganglion cells after peripheral nerve transplantation in adult mice. J. Neurosci. 22:2002;4468-4477
    • (2002) J. Neurosci. , vol.22 , pp. 4468-4477
    • Inoue, T.1    Hosokawa, M.2    Morigiwa, K.3    Ohashi, Y.4    Fukuda, Y.5
  • 21
    • 0030851891 scopus 로고    scopus 로고
    • Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat
    • Isenmann S., Wahl C., Krajewski S., Reed J.C., Bähr M. Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat. Eur. J. Neurosci. 9:1997;1763-1772
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1763-1772
    • Isenmann, S.1    Wahl, C.2    Krajewski, S.3    Reed, J.C.4    Bähr, M.5
  • 22
    • 0032130217 scopus 로고    scopus 로고
    • Short communication: Protection of axotomized retinal ganglion cells by adenovirally delivered BDNF in vivo
    • Isenmann S., Klöcker N., Gravel C., Bähr M. Short communication: protection of axotomized retinal ganglion cells by adenovirally delivered BDNF in vivo. Eur. J. Neurosci. 10:1998;2751-2756
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 2751-2756
    • Isenmann, S.1    Klöcker, N.2    Gravel, C.3    Bähr, M.4
  • 23
    • 0038555748 scopus 로고    scopus 로고
    • Molecular determinants of retinal ganglion cell development, survival, and regeneration
    • Isenmann S., Kretz A., Cellerino A. Molecular determinants of retinal ganglion cell development, survival, and regeneration. Prog. Retinal Eye Res. 22:2003;483-543
    • (2003) Prog. Retinal Eye Res. , vol.22 , pp. 483-543
    • Isenmann, S.1    Kretz, A.2    Cellerino, A.3
  • 24
    • 0344333441 scopus 로고    scopus 로고
    • Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo
    • Kermer P., Klöcker N., Labes M., Bähr M. Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo. J. Neurosci. 18:1998;4656-4662
    • (1998) J. Neurosci. , vol.18 , pp. 4656-4662
    • Kermer, P.1    Klöcker, N.2    Labes, M.3    Bähr, M.4
  • 25
    • 0038076001 scopus 로고    scopus 로고
    • Axon regeneration in young adult mice lacking Nogo-A/B
    • Kim J.E., Li S., GrandPre T., Qiu D., Strittmatter S.M. Axon regeneration in young adult mice lacking Nogo-A/B. Neuron. 38:2003;153-156
    • (2003) Neuron , vol.38 , pp. 153-156
    • Kim, J.E.1    Li, S.2    Grandpre, T.3    Qiu, D.4    Strittmatter, S.M.5
  • 26
    • 0030709339 scopus 로고    scopus 로고
    • In vivo neurotrophic effects of GDNF on axotomized retinal ganglion cells
    • Klöcker N., Bräunling F., Isenmann S., Bähr M. In vivo neurotrophic effects of GDNF on axotomized retinal ganglion cells. NeuroReport. 8:1997;3439-3442
    • (1997) NeuroReport , vol.8 , pp. 3439-3442
    • Klöcker, N.1    Bräunling, F.2    Isenmann, S.3    Bähr, M.4
  • 27
    • 2342459207 scopus 로고    scopus 로고
    • A novel primary culture technique for adult RGCs for evaluation of axon regeneration in rodents
    • (in press)
    • Kretz A., Hermening S., Isenmann S. A novel primary culture technique for adult RGCs for evaluation of axon regeneration in rodents. J. Neurosci. Methods. 2004;. (in press)
    • (2004) J. Neurosci. Methods
    • Kretz, A.1    Hermening, S.2    Isenmann, S.3
  • 28
    • 17644432519 scopus 로고    scopus 로고
    • Transduction of axotomized retinal ganglion cells by adenoviral vector administration at the optic nerve stump: An in vivo model system for the inhibition of neuronal apoptotic cell death
    • Kügler S., Klöcker N., Kermer P., Isenmann S., Bähr M. Transduction of axotomized retinal ganglion cells by adenoviral vector administration at the optic nerve stump: an in vivo model system for the inhibition of neuronal apoptotic cell death. Gene Ther. 6:1999;1759-1767
    • (1999) Gene Ther. , vol.6 , pp. 1759-1767
    • Kügler, S.1    Klöcker, N.2    Kermer, P.3    Isenmann, S.4    Bähr, M.5
  • 29
    • 0035151061 scopus 로고    scopus 로고
    • Neuron-specific expression of therapeutic proteins: Evaluation of different cellular promoters in recombinant adenoviral vectors
    • Kügler S., Meyn L., Holzmüller H., Gerhardt E., Isenmann S., Schulz J.B., Bähr M. Neuron-specific expression of therapeutic proteins: evaluation of different cellular promoters in recombinant adenoviral vectors. Mol. Cell. Neurosci. 17:2001;78-96
    • (2001) Mol. Cell. Neurosci. , vol.17 , pp. 78-96
    • Kügler, S.1    Meyn, L.2    Holzmüller, H.3    Gerhardt, E.4    Isenmann, S.5    Schulz, J.B.6    Bähr, M.7
  • 31
    • 84938057807 scopus 로고    scopus 로고
    • Different signaling pathways mediate regenerative versus developmental sensory axon growth
    • Liu R.Y., Snider W.D Different signaling pathways mediate regenerative versus developmental sensory axon growth. J. Neurosci. 21(RC164):2001;1-5
    • (2001) J. Neurosci. , vol.21 , Issue.RC164 , pp. 1-5
    • Liu, R.Y.1    Snider, W.D.2
  • 32
    • 0037119581 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor
    • Liu B.P., Fournier A., GrandPre T., Strittmatter S.M. Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor. Science. 297:2002;1190-1193
    • (2002) Science , vol.297 , pp. 1190-1193
    • Liu, B.P.1    Fournier, A.2    Grandpre, T.3    Strittmatter, S.M.4
  • 33
    • 0035114317 scopus 로고    scopus 로고
    • Bcl-2 overexpression per se does not promote regeneration of neonatal crushed optic fibers
    • Lodovichi C., Di Cristo G., Cenni M.C., Maffei L. Bcl-2 overexpression per se does not promote regeneration of neonatal crushed optic fibers. Eur. J. Neurosci. 13:2001;833-838
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 833-838
    • Lodovichi, C.1    Di Cristo, G.2    Cenni, M.C.3    Maffei, L.4
  • 34
    • 0027944004 scopus 로고
    • Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
    • Martinou J.C., Dubois-Dauphin M., Staple J.K., Rodriguez I., Frankowski H., et al. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron. 13:1994;1017-1030
    • (1994) Neuron , vol.13 , pp. 1017-1030
    • Martinou, J.C.1    Dubois-Dauphin, M.2    Staple, J.K.3    Rodriguez, I.4    Frankowski, H.5
  • 35
    • 0028841089 scopus 로고
    • Injury-induced proteoglycans inhibit the potential for laminin-mediated axon growth on astrocytic scars
    • Mc Keon R., Hoke A., Silver J. Injury-induced proteoglycans inhibit the potential for laminin-mediated axon growth on astrocytic scars. Exp. Neurol. 136:1995;32-43
    • (1995) Exp. Neurol. , vol.136 , pp. 32-43
    • Mc Keon, R.1    Hoke, A.2    Silver, J.3
  • 36
    • 0028178385 scopus 로고
    • Bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS
    • Merry D.E., Veis D.J., Hickey W.F., Korsmeyer S.J. bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development. 120:1994;301-311
    • (1994) Development , vol.120 , pp. 301-311
    • Merry, D.E.1    Veis, D.J.2    Hickey, W.F.3    Korsmeyer, S.J.4
  • 38
    • 0033570319 scopus 로고    scopus 로고
    • Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycans
    • Niederöst B.P., Zimmermann D.R., Schwab M.E., Bandtlow C.E. Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycans. J. Neurosci. 19:1999;8979-8989
    • (1999) J. Neurosci. , vol.19 , pp. 8979-8989
    • Niederöst, B.P.1    Zimmermann, D.R.2    Schwab, M.E.3    Bandtlow, C.E.4
  • 39
    • 0037428719 scopus 로고    scopus 로고
    • The effect of caspase inhibitors and neurotrophic factors on damaged retinal ganglion cells
    • Oshitari T., Adachi-Usami E. The effect of caspase inhibitors and neurotrophic factors on damaged retinal ganglion cells. NeuroReport. 14:2003;289-292
    • (2003) NeuroReport , vol.14 , pp. 289-292
    • Oshitari, T.1    Adachi-Usami, E.2
  • 40
    • 0042769080 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of Bcl-xL impedes neurite regeneration in vitro
    • Oshitari T., Okada S., Tokuhisa T., Adachi-Usami E. Adenovirus-mediated gene transfer of Bcl-xL impedes neurite regeneration in vitro. NeuroReport. 14:2003;1159-1162
    • (2003) NeuroReport , vol.14 , pp. 1159-1162
    • Oshitari, T.1    Okada, S.2    Tokuhisa, T.3    Adachi-Usami, E.4
  • 43
    • 0033579301 scopus 로고    scopus 로고
    • Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
    • Riccio A., Ahn S., Davenport C.M., Blendy J.A., Ginty D.D. Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science. 286:1999;2358-2361
    • (1999) Science , vol.286 , pp. 2358-2361
    • Riccio, A.1    Ahn, S.2    Davenport, C.M.3    Blendy, J.A.4    Ginty, D.D.5
  • 44
    • 0036460130 scopus 로고    scopus 로고
    • Dose-dependent rescue of axotomized rat retinal ganglion cells by adenovirus-mediated expression of glial cell-line derived neurotrophic factor in vivo
    • Schmeer C., Straten G., Kügler S., Gravel C., Bähr M., Isenmann S. Dose-dependent rescue of axotomized rat retinal ganglion cells by adenovirus-mediated expression of glial cell-line derived neurotrophic factor in vivo. Eur. J. Neurosci. 15:2002;637-643
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 637-643
    • Schmeer, C.1    Straten, G.2    Kügler, S.3    Gravel, C.4    Bähr, M.5    Isenmann, S.6
  • 46
    • 0034141623 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of Bcl-X(L) protects neuronal cells from Bax-induced apoptosis
    • Shinoura N., Satou R., Yoshida Y., Asai A., Kirino T., Hamada H. Adenovirus-mediated transfer of Bcl-X(L) protects neuronal cells from Bax-induced apoptosis. Exp. Cell Res. 254:2000;221-231
    • (2000) Exp. Cell Res. , vol.254 , pp. 221-231
    • Shinoura, N.1    Satou, R.2    Yoshida, Y.3    Asai, A.4    Kirino, T.5    Hamada, H.6
  • 48
    • 0021943952 scopus 로고
    • Lengthy regrowth of cut axons from ganglion cells after peripheral nerve transplantation into the retina of adult rats
    • So K.F., Aguayo A.J. Lengthy regrowth of cut axons from ganglion cells after peripheral nerve transplantation into the retina of adult rats. Brain Res. 328:1985;349-354
    • (1985) Brain Res. , vol.328 , pp. 349-354
    • So, K.F.1    Aguayo, A.J.2
  • 49
    • 0036449530 scopus 로고    scopus 로고
    • Potential synergistic protection of retinal ganglion cells from axotomy-induced apoptosis by adenoviral administration of glial cell line-derived neurotrophic factor and X-chromosome-linked inhibitor of apoptosis
    • Straten G., Schmeer C., Kretz A., Gerhardt E., Kügler S., Schulz J.B., Gravel C., Bähr M., Isenmann S. Potential synergistic protection of retinal ganglion cells from axotomy-induced apoptosis by adenoviral administration of glial cell line-derived neurotrophic factor and X-chromosome-linked inhibitor of apoptosis. Neurobiol. Dis. 11:2002;123-133
    • (2002) Neurobiol. Dis. , vol.11 , pp. 123-133
    • Straten, G.1    Schmeer, C.2    Kretz, A.3    Gerhardt, E.4    Kügler, S.5    Schulz, J.B.6    Gravel, C.7    Bähr, M.8    Isenmann, S.9
  • 50
    • 0023410632 scopus 로고
    • Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat
    • Vidal-Sanz M., Bray G.M., Villegas-Perez M.P., Thanos S., Aguayo A.J. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J. Neurosci. 7:1987;2894-2909
    • (1987) J. Neurosci. , vol.7 , pp. 2894-2909
    • Vidal-Sanz, M.1    Bray, G.M.2    Villegas-Perez, M.P.3    Thanos, S.4    Aguayo, A.J.5
  • 51
    • 0027463379 scopus 로고
    • Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats
    • Villegas-Perez M.P., Vidal-Sanz M., Rasminsky M., Bray G.M., Aguayo A.J. Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats. J. Neurobiol. 24:1993;23-36
    • (1993) J. Neurobiol. , vol.24 , pp. 23-36
    • Villegas-Perez, M.P.1    Vidal-Sanz, M.2    Rasminsky, M.3    Bray, G.M.4    Aguayo, A.J.5


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