T-cell-specific expression of kinase-defective Eph-family receptor protein, EphB6 in normal as well as transformed hematopoietic cells

Growth Factors

Volumn 18, Issue 1, 2000, Pages 63-78

  Shimoyama, Manabu ^a   Matsuoka, Hiroshi ^a   Tamekane, Akira ^a   Ito, Mitsuhiro ^a   Nobuko, Iwata ^a   Inoue, Ryuichi ^a   Chihara, Kazuo ^a   Furuya, Akiko ^b   Hanai, Nobuo ^b   Matsui, Toshimitsu ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

EphB6; Hematopoiesis; Leukemia lymphoma; T lymphocyte; Thymocyte

Indexed keywords

PROTEIN TYROSINE KINASE; RECEPTOR PROTEIN;

ARTICLE; FLOW CYTOMETRY; GENE EXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA; LYMPHOMA; PRIORITY JOURNAL; T LYMPHOCYTE; THYMOCYTE;

EID: 17144449379     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.3109/08977190009003234     Document Type: Article

References (48)

1. Aaronson, S.A. (1991) Growth factors and cancer. Science 254, 1146-1153.
2. Aasheim, H.C., Terstappen, L.W.M.M. and Logtenberg, T. (1997) Regulated expression of the Eph-related receptor tyrosine kinase Hek11 in early human B lymphopoiesis. Blood 90, 3613-3622.
3. Alimandi, M., Romano, A., Curia, M.C., Muraro, R., Fedi, P., Aaronson, S.A., Di Fiore, P.P. and Kraus, M.H. (1995) Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 10, 1813-1821.
4. Altiok, N., Bessereau, J.L. and Changeux, J.P. (1995) ErbB3 and ErbB2/neu mediate the effect of heregulin on acetylcholine receptor gene expression in muscle: differential expression at the end plate. EMBO J. 14, 4258-4266.
5. Anderson, G., Moore, N.C., Owen, J.J.T. and Jenkinson, E.J. (1996) Cellular interactions in thymocyte development. Annu. Rev. Immunol. 14, 73-99.
6. Andres, A.C., Reid, H.H., Zurcher, G., Blaschke, R.J., Albrecht, D. and Ziemiecki, A. (1994) Expression of two novel eph-related receptor protein tyrosine kinases in mammary gland development and carcinogenesis. Oncogene 9, 1461-1467.
7. Bennett, B.D., Wang, Z., Kuang, W.J., Wang, A., Groopman, J.E., Goeddel, D.V. and Scadden, D.T. (1994) Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily. J. Biol. Chem. 269, 14 211-14 218.
8. Berclaz, G., Andres, A.C., Albrecht, D., Dreher, E., Ziemiecki, A., Gusterson, B.A. and Crompton, M.R. (1996) Expression of the receptor protein tyrosine kinase myk-l/htk in normal and malignant mammary epithelium. Biochem. Biophys. Res. Commun. 226, 869-875.
9. Boyd, A.W., Ward, L.D., Wicks, I.P., Simpson, R.J., Salvaris, E., Wilks, A., Welch, K., Loudovaris, M., Rockman, S. and Busmanis, I. (1992) Isolation and characterization of a novel receptor-type protein tyrosine kinase (hek) from a human pre-B cell line. J. Biol. Chem. 267, 3262-3267.
10. Brambilla, R., Schnapp, A., Casagranda, F., Labrador, J.P., Bergemann, A.D., Flanagan, J.G., Pasquale, E.B. and Klein, R. (1995) Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. EMBO J. 14, 3116-3126.
11. Chou, Y.H. and Hayman, M.J. (1991) Characterization of a member of the immunoglobulin gene superfamily that possibly represents an additional class of growth factor receptor. Proc. Natl. Acad. Sci. USA 88, 4897-4901.
12. Ciossek, T., Lerch, M.M. and Ullrich, A. (1995) Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family. Oncogene 11, 2085-2095.
13. Eph Nomenclature Committee (1997) Unified nomenclature for Eph family receptors and their ligands, the ephrins [letter]. Cell 90, 403-404.
14. Flanagan, J.G. and Vanderhaeghen, P. (1998) The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci. 21, 309-345.
15. Fox, G.M., Holst, P.L., Chute, H.T., Lindberg, R.A., Janssen, A.M., Basu, R. and Welcher, A.A. (1995) cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases. Oncogene 10, 897-905.
16. Giebel, L.B. and Spritz, R.A. (1991) Mutation of the KIT (mast/ stem cell growth factor receptor) protooncogene in human piebaldism. Proc. Natl. Acad. Sci. USA 88, 8696-8699.
17. Gurniak, C.B. and Berg, L.J. (1996) A new member of the Eph family of receptors that lacks protein tyrosine kinase activity. Oncogene 13, 777-786.
18. Guy, P.M., Platko, J.V., Cantley, L.C., Cerione, R.A. and Carraway, K.L., III. (1994) Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc. Natl. Acad. Sci. USA 91, 8132-8136.
19. Henkemeyer, M., Marengere, L.E., McGlade, J., Olivier, J.P., Conlon, R.A., Holmyard, D.P., Letwin, K. and Pawson, T. (1994) Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis. Oncogene 9, 1001-1014.
20. Henkemeyer, M., Orioli, D., Henderson, J.T., Saxton, T.M., Roder, J., Pawson, T. and Klein, R. (1996) Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell 86, 35-46.
21. Hirai, H., Maru, Y., Hagiwara, K., Nishida, J. and Takaku, F. (1987) A novel putative tyrosine kinase receptor encoded by the eph gene. Science 238, 1717-1720.
22. Holland, S.J., Gale, N.W., Mbamalu, G., Yancopoulos, G.D., Henkemeyer, M. and Pawson, T. (1996) Bidirectional signaling through the EPH-family receptor Nuk and its transmcmbrane ligands. Nature 383, 722-725.
23. Inada, T., Iwama, A., Sakano, S., Ohno, M., Sawada, K. and Suda, T. (1997) Selective expression of the receptor tyrosinc kinase, HTK, on human erythroid progenitor cells. Blood 89, 2757-2765.
24. Iwase, T., Tanaka, M., Suzuki, M., Naito, Y., Sugimura, H. and Kino (1993) Identification of protein-tyrosine kinase genes preferentially expressed in embryo stomach and gastric cancer. Biochem. Biophys. Res. Commun. 194, 698-705.
25. Jcnkinson, E.J., Anderson, G. and Owen, J.J.T. (1992) Studies on T cell maturation on defined thymic stromal cell populations in vitro. J. Exp. Med. 176, 845-853.
26. Kiyokawa, E., Takai, S., Tanaka, M., Iwase, T., Suzuki, M., Xiang, Y.Y., Naito, Y., Yamada, K., Sugimura, H. and Kino, I. (1994) Ovcrcxpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors. Cancer Res. 54, 3645-3650.
27. Kraus, M.H., Issing, W., Miki, T., Popescu, N.C. and Aaronson, S.A. (1989) Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc. Natl. Acad. Sci. USA 86, 9193-9197.
28. Lickliter, J.D., Smith, F.M., Olsson, J.E., Mackwell, K.L. and Boyd, A.W. (1996) Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases. Proc. Natl. Acad. Sci. USA 93, 145-150.
29. Maru, Y., Hirai, H., Yoshida, M.C. and Takaku, F. (1988) Evolution, expression, and chromosomal location of a novel receptor tyrosine kinase gene, eph. Mol. Cell. Biol. 8, 3770-3776.
30. Maru, Y., Hirai, H. and Takaku, F. (1990) Overexpression confers an oncogenic potential upon the eph gene. Oncogene 5, 445-447.
31. Matsuoka, H., Iwata, N., Ito, M., Shimoyama, M., Nagata, A., Chihara, K., Takai, S. and Matsui, T. (1997) Expression of a kinase-defective Eph-like receptor in the normal human brain. Biochem. Biophys. Res. Commun. 235, 487-492.
32. Mellitzer, G., Xu, Q. and Wilkinson, D.G. (1999) Eph receptor and ephrins restrict cell intermingling and communication. Nature 400, 77-81.
33. Minowada, J. (1988) Leukemia cell lines. Cancer Rev. 10, 1-10.
34. Moller, D.E. and Flier, J.S. (1991) Insulin resistance-mechanisms, syndromes, and implications. N. Engl. J. Med. 325, 938-948.
35. Mossie, K., Jallal, B., Alves, F., Sures, I., Plowman, G.D. and Ullrich, A. (1995) Colon carcinoma kinase-4 defines a new subclass of the receptor tyrosine kinase family. Oncogene 11, 2179-2184.
36. Nakamoto, M., Cheng, H.J., Friedman, G.C., McLaughlin, T., Hansen, M.J., Yoon, C.H., O'Leary, D.D.M and Flanagan, J.G. (1996) Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo. Cell 86, 755-766.
37. Pandey, A., Shao, H., Marks, R.M., Polverini, P.J. and Dixit, V.M. (1995) Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis. Science 268, 567-569.
38. Rajkumar, T. and Gullick, W.J. (1994) A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. Br. J. Cancer 70, 459-465.
39. Sajjadi, F.G. and Pasquale, E.B. (1993) Five novel avian Ephrelated tyrosine kinases are differentially expressed. Oncogene 8, 1807-1813.
40. Schlessinger, J. and Ullrich, A. (1992) Growth factor signaling by receptor tyrosine kinases. Neuron 9, 383-391.
41. Shao, H., Pandey, A., O'Shea, K.S., Seldin, M. and Dixit, V.M. (1995) Characterization of B61, the ligand for the Eck receptor protein-tyrosine kinase. J. Biol. Chem. 270, 5636-5641.
42. 42 spotting phenotype results from a missense mutation in the c-kit receptor kinase. Science 247, 209-212.
43. Tuzi, N.L. and Gullick, W.J. (1994) eph, the largest known family of putative growth factor receptors. Br. J. Cancer 69, 417-421.
44. von Boehmer, H. (1990) Developmental biology of Tcells in T cell-receptor transgenic mice. Annu. Rev. Immunol 8, 531-556.
45. Wang, H.U., Chen, Z.F. and Anderson, D.J. (1998) Molecular distinction and angiogenetic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor EphB4. Cell 93, 741-753.
46. Wicks, I.P., Wilkinson, D., Salvaris, E. and Boyd, A.W. (1992) Molecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines. Proc. Natl. Acad. Sci. USA 89, 1611-1615.
47. Xu, Q., Mellitzer, G., Robinson, V. and Wilkinson, D.G. (1999) In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins. Nature 399, 267-271.
48. Zhou, R. (1998) The Eph family receptors and ligands. Pharmacol. Ther. 77, 151-181.