-
1
-
-
0029294009
-
Intracellular antibodies (intrabodies) as research reagents and therapeutic molecules for gene therapy
-
Marasco W.A., Intracellular antibodies (intrabodies) as research reagents and therapeutic molecules for gene therapy, Immunotechnology, 1: 1-19, 1995
-
(1995)
Immunotechnology
, vol.1
, pp. 1-19
-
-
Marasco, W.A.1
-
2
-
-
0141521636
-
Intrabody and intrakine strategies for molecular therapy
-
Wheeler Y.Y., Chen S.Y., Sane D.C., Intrabody and intrakine strategies for molecular therapy, Mol Ther, 8: 355-366, 2003
-
(2003)
Mol. Ther.
, vol.8
, pp. 355-366
-
-
Wheeler, Y.Y.1
Chen, S.Y.2
Sane, D.C.3
-
3
-
-
0024293979
-
Single-chain antigen-binding proteins
-
Bird R.E., Hardman K.D., Jacobson J.W., Johnson S., Kaufman B.M., Lee S.M., Lee T., Pope S.H., Riordan G.S., Whitlow M., Single-chain antigen-binding proteins, Science, 242: 423-426, 1988
-
(1988)
Science
, vol.242
, pp. 423-426
-
-
Bird, R.E.1
Hardman, K.D.2
Jacobson, J.W.3
Johnson, S.4
Kaufman, B.M.5
Lee, S.M.6
Lee, T.7
Pope, S.H.8
Riordan, G.S.9
Whitlow, M.10
-
4
-
-
0043123378
-
Single domain intracellular antibodies: A minimal fragment for direct in vivo selection of antigen-specific intrabodies
-
Tanaka T., Lobato M.N., Rabbitts T.H., Single domain intracellular antibodies: a minimal fragment for direct in vivo selection of antigen-specific intrabodies, J Mol Biol, 331: 1109-1120, 2003
-
(2003)
J. Mol. Biol.
, vol.331
, pp. 1109-1120
-
-
Tanaka, T.1
Lobato, M.N.2
Rabbitts, T.H.3
-
5
-
-
2942724405
-
Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity
-
Aires da Silva F., Santa-Marta M., Freitas-Vieira A., Mascarenhas P., Barahona I., Moniz-Pereira J., Gabuzda D., Goncalves J., Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity, J. Mol. Biol., 340: 525-542, 2004
-
(2004)
J. Mol. Biol.
, vol.340
, pp. 525-542
-
-
Aires Da Silva, F.1
Santa-Marta, M.2
Freitas-Vieira, A.3
Mascarenhas, P.4
Barahona, I.5
Moniz-Pereira, J.6
Gabuzda, D.7
Goncalves, J.8
-
6
-
-
0024022171
-
A new means of inducibly inactivating a cellular protein
-
Carlson J.R., A new means of inducibly inactivating a cellular protein, Mol. Cell Biol., 8: 2638-2646, 1988
-
(1988)
Mol. Cell Biol.
, vol.8
, pp. 2638-2646
-
-
Carlson, J.R.1
-
7
-
-
0037416179
-
Intrabodies based on intracellular capture frameworks that bind the RAS protein with high affinity and impair oncogenic transformation
-
Tanaka T., Rabbitts T.H., Intrabodies based on intracellular capture frameworks that bind the RAS protein with high affinity and impair oncogenic transformation, EMBO J., 22: 1025-1035, 2003
-
(2003)
EMBO J.
, vol.22
, pp. 1025-1035
-
-
Tanaka, T.1
Rabbitts, T.H.2
-
8
-
-
0032521206
-
Intracellular expression of an antibody fragment-neutralizing p21 ras promotes tumor regression
-
Cochet O., Kenigsberg M., Delumeau I., Virone-Oddos A., Multon M.C., Fridman W.H., Schweighoffer F., Teillaud J.L., Tocque B., Intracellular expression of an antibody fragment-neutralizing p21 ras promotes tumor regression, Cancer. Res., 58: 1170-1176, 1988
-
(1988)
Cancer Res.
, vol.58
, pp. 1170-1176
-
-
Cochet, O.1
Kenigsberg, M.2
Delumeau, I.3
Virone-Oddos, A.4
Multon, M.C.5
Fridman, W.H.6
Schweighoffer, F.7
Teillaud, J.L.8
Tocque, B.9
-
9
-
-
0028839655
-
Targeted tumor killing via an intracellular antibody against erbB-2
-
Deshane J., Siegal G.P., Alvarez R.D., Wang M.H., Feng M., Cabrera G., Liu T., Kay M., Curiel D.T., Targeted tumor killing via an intracellular antibody against erbB-2, J. Clin. Invest., 96: 2980-2989, 1995
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 2980-2989
-
-
Deshane, J.1
Siegal, G.P.2
Alvarez, R.D.3
Wang, M.H.4
Feng, M.5
Cabrera, G.6
Liu, T.7
Kay, M.8
Curiel, D.T.9
-
10
-
-
0027275371
-
Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody
-
Marasco W.A., Haseltine W.A., Chen S.Y., Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody, Proc. Natl. Acad. Sci. U. S. A., 90: 7889-7893, 1993
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 7889-7893
-
-
Marasco, W.A.1
Haseltine, W.A.2
Chen, S.Y.3
-
11
-
-
0029064110
-
Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro
-
Maciejewski J.P., Weichold F.F., Young N.S., Cara A., Zella D., Reitz M.S., Gallo R.C., Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro, Nat. Med., 1: 667-673, 1995
-
(1995)
Nat. Med.
, vol.1
, pp. 667-673
-
-
Maciejewski, J.P.1
Weichold, F.F.2
Young, N.S.3
Cara, A.4
Zella, D.5
Reitz, M.S.6
Gallo, R.C.7
-
12
-
-
0029616053
-
Intracellular immunization against HIV-1 infection of human T lymphocytes: Utility of anti-rev single-chain variable fragments
-
Duan L., Zhu M., Bagasra O., Pomerantz R.J., Intracellular immunization against HIV-1 infection of human T lymphocytes: utility of anti-rev single-chain variable fragments, Hum. Gene. Ther., 6: 1561-1573, 1995
-
(1995)
Hum. Gene. Ther.
, vol.6
, pp. 1561-1573
-
-
Duan, L.1
Zhu, M.2
Bagasra, O.3
Pomerantz, R.J.4
-
13
-
-
0036831289
-
Stem cell medicine encounters the immune system
-
Bradley J.A., Bolton E.M., Pedersen R.A., Stem cell medicine encounters the immune system, Nat. Rev. Immuno., 2: 859-871, 2002
-
(2002)
Nat. Rev. Immuno.
, vol.2
, pp. 859-871
-
-
Bradley, J.A.1
Bolton, E.M.2
Pedersen, R.A.3
-
14
-
-
0345255186
-
An experimental platform for studying growth and invasiveness of tumor cells within teratomas derived from human embryonic stem cells
-
Tzukerman M., Rosenberg T., Ravel Y., Reiter I., Coleman R., Skorecki K., An experimental platform for studying growth and invasiveness of tumor cells within teratomas derived from human embryonic stem cells, Proc Natl. Acad. Sci. U. S. A., 100: 13507-13512, 2003
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13507-13512
-
-
Tzukerman, M.1
Rosenberg, T.2
Ravel, Y.3
Reiter, I.4
Coleman, R.5
Skorecki, K.6
-
15
-
-
2442637454
-
An overview and synopsis of techniques for directing stem cell differentiation in vitro
-
Heng B.C., Cao T., Haider H.K., Wang D.Z., Sim E.K., Ng S.C., An overview and synopsis of techniques for directing stem cell differentiation in vitro, Cell Tissue Res., 315: 291-303, 2004
-
(2004)
Cell Tissue Res.
, vol.315
, pp. 291-303
-
-
Heng, B.C.1
Cao, T.2
Haider, H.K.3
Wang, D.Z.4
Sim, E.K.5
Ng, S.C.6
-
16
-
-
0036850818
-
Adult stem cells: Assessing the case for pluripotency
-
Verfaillie C.M., Adult stem cells: assessing the case for pluripotency, Trends Cell Biol., 12: 502-508, 2002
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 502-508
-
-
Verfaillie, C.M.1
-
17
-
-
4744373229
-
Noise amidst the silence: Off-target effects of siRNAs?
-
Jackson A.L., Linsley P.S., Noise amidst the silence: off-target effects of siRNAs? Trends Genet., 20: 521-524, 2004
-
(2004)
Trends Genet.
, vol.20
, pp. 521-524
-
-
Jackson, A.L.1
Linsley, P.S.2
-
18
-
-
10644284795
-
RNA interference and double-stranded-RNA-activated pathways
-
Sledz C.A., Williams B.R., RNA interference and double-stranded-RNA- activated pathways, Biochem. Soc. Trans., 32: 952-956, 2004
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 952-956
-
-
Sledz, C.A.1
Williams, B.R.2
-
19
-
-
2442641279
-
Many commonly used siRNAs risk off-target activity
-
Snove O., Holen T., Many commonly used siRNAs risk off-target activity, Biochem. Biophys. Res. Commun., 319: 256-263, 2004
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.319
, pp. 256-263
-
-
Snove, O.1
Holen, T.2
-
20
-
-
0347623204
-
Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)
-
Persengiev S.P., Zhu X., Green M.R., Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs), RNA., 10: 12-18, 2004
-
(2004)
RNA
, vol.10
, pp. 12-18
-
-
Persengiev, S.P.1
Zhu, X.2
Green, M.R.3
-
21
-
-
0032771488
-
The selection of intracellular antibodies
-
Cattaneo A., Biocca S., The selection of intracellular antibodies, Trends Biotechnol., 17: 115-121, 1999
-
(1999)
Trends Biotechnol.
, vol.17
, pp. 115-121
-
-
Cattaneo, A.1
Biocca, S.2
-
22
-
-
0033638333
-
Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins
-
Zhou P., Bogacki R., McReynolds L., Howley P.M., Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins, Mol. Cell., 6: 751-756, 2000
-
(2000)
Mol. Cell.
, vol.6
, pp. 751-756
-
-
Zhou, P.1
Bogacki, R.2
McReynolds, L.3
Howley, P.M.4
-
23
-
-
0034710984
-
Intracellular antibody-caspase-mediated cell killing: An approach for application in cancer therapy
-
Tse E., Rabbitts T.H., Intracellular antibody-caspase-mediated cell killing: an approach for application in cancer therapy, Proc. Natl. Acad. Sci. U. S. A., 97: 12266-12271, 2000
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 12266-12271
-
-
Tse, E.1
Rabbitts, T.H.2
-
24
-
-
12144288049
-
Derivation of embryonic stem-cell lines from human blastocysts
-
Cowan C.A., Klimanskaya I., McMahon J., Atienza J., Witmyer J., Zucker J.P., Wang S., Morton C.C., McMahon A.P., Powers D., Melton D.A., Derivation of embryonic stem-cell lines from human blastocysts, N. Engl. J. Med., 350: 1353-1356, 2004
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1353-1356
-
-
Cowan, C.A.1
Klimanskaya, I.2
McMahon, J.3
Atienza, J.4
Witmyer, J.5
Zucker, J.P.6
Wang, S.7
Morton, C.C.8
McMahon, A.P.9
Powers, D.10
Melton, D.A.11
-
25
-
-
12144286557
-
Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst
-
Hwang W.S., Ryu Y.J., Park J.H., Park E.S., Lee E.G, Koo J.M., Jeon H.Y., Lee B.C., Kang S.K., Kim S.J., Ahn C., Hwang J.H., Park K.Y., Cibelli J.B., Moon S.Y., Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst, Science, 303: 1669-1674, 2004
-
(2004)
Science
, vol.303
, pp. 1669-1674
-
-
Hwang, W.S.1
Ryu, Y.J.2
Park, J.H.3
Park, E.S.4
Lee, E.G.5
Koo, J.M.6
Jeon, H.Y.7
Lee, B.C.8
Kang, S.K.9
Kim, S.J.10
Ahn, C.11
Hwang, J.H.12
Park, K.Y.13
Cibelli, J.B.14
Moon, S.Y.15
-
26
-
-
85047699270
-
Intrabody-mediated phenotypic knockout of major histocompatibility complex class I expression in human and monkey cell lines and in primary human keratinocytes
-
Mhashilkar A.M., Doebis C., Seifert M., Busch A., Zani C., Soo Hoo J., Nagy M., Ritter T., Volk H.D., Marasco W.A., Intrabody-mediated phenotypic knockout of major histocompatibility complex class I expression in human and monkey cell lines and in primary human keratinocytes, Gene Ther., 9: 307-319, 2002
-
(2002)
Gene Ther.
, vol.9
, pp. 307-319
-
-
Mhashilkar, A.M.1
Doebis, C.2
Seifert, M.3
Busch, A.4
Zani, C.5
Soo Hoo, J.6
Nagy, M.7
Ritter, T.8
Volk, H.D.9
Marasco, W.A.10
-
27
-
-
7944238552
-
Decline of surface MHC I by adenoviral gene transfer of anti-MHC I intrabodies in human endothelial cells - New perspectives for the generation of universal donor cells for tissue transplantation
-
Beyer F., Doebis C., Busch A., Ritter T., Mhashilkar A., Marasco W.M., Laube H., Volk H.D., Seifert M., Decline of surface MHC I by adenoviral gene transfer of anti-MHC I intrabodies in human endothelial cells-new perspectives for the generation of universal donor cells for tissue transplantation, J. Gene Med., 6: 616-23, 2004
-
(2004)
J. Gene Med.
, vol.6
, pp. 616-623
-
-
Beyer, F.1
Doebis, C.2
Busch, A.3
Ritter, T.4
Mhashilkar, A.5
Marasco, W.M.6
Laube, H.7
Volk, H.D.8
Seifert, M.9
-
28
-
-
0031016269
-
Intrabodies: Turning the humoral immune system outside in for intracellular immunization
-
Marasco W.A., Intrabodies: turning the humoral immune system outside in for intracellular immunization, Gene Ther., 4: 11-15, 1997
-
(1997)
Gene Ther.
, vol.4
, pp. 11-15
-
-
Marasco, W.A.1
-
29
-
-
0036200587
-
Liver-enriched transcription factors in liver function and development. I, the hepatocyte nuclear factor network and liver-specific gene expression
-
Schrem H., Klempnauer J., Borlak J., Liver-enriched transcription factors in liver function and development. I, The hepatocyte nuclear factor network and liver-specific gene expression, Pharmacol Rev., 54: 1129-1158, 2002
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 1129-1158
-
-
Schrem, H.1
Klempnauer, J.2
Borlak, J.3
-
30
-
-
0036304223
-
Transcriptional codes and the control of neuronal identity
-
Shirasaki R., Pfaff S.L., Transcriptional codes and the control of neuronal identity, Annu. Rev. Neurosci., 25: 251-281, 2002
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 251-281
-
-
Shirasaki, R.1
Pfaff, S.L.2
-
31
-
-
0038030960
-
Cardiac specific differentiation of mouse embryonic stem cells
-
Sachinidis A., Fleischmann B.K., Kolossov E., Wartenberg M., Sauer H., Hescheler J., Cardiac specific differentiation of mouse embryonic stem cells, Cardiovasc. Res., 58: 2278-2291, 2003
-
(2003)
Cardiovasc. Res.
, vol.58
, pp. 2278-2291
-
-
Sachinidis, A.1
Fleischmann, B.K.2
Kolossov, E.3
Wartenberg, M.4
Sauer, H.5
Hescheler, J.6
-
32
-
-
0031104994
-
SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse
-
Ng L.J., Wheatley S., Muscat G.E., Conway-Campbell J., Bowles J., Wright E., Bell D.M., Tam P.P., Cheah K.S., Koopman P., SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse, Dev Biol., 183: 108-121, 1997
-
(1997)
Dev. Biol.
, vol.183
, pp. 108-121
-
-
Ng, L.J.1
Wheatley, S.2
Muscat, G.E.3
Conway-Campbell, J.4
Bowles, J.5
Wright, E.6
Bell, D.M.7
Tam, P.P.8
Cheah, K.S.9
Koopman, P.10
-
33
-
-
0036830491
-
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
-
Akiyama H., Chaboissier M.C., Martin J.F., Schedl A., de Crombrugghe B., The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6, Genes Dev., 16: 2813-2828, 2002
-
(2002)
Genes Dev.
, vol.16
, pp. 2813-2828
-
-
Akiyama, H.1
Chaboissier, M.C.2
Martin, J.F.3
Schedl, A.4
De Crombrugghe, B.5
-
34
-
-
0037059614
-
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
-
Nakashima K., Zhou X., Kunkel G., Zhang Z., Deng J.M., Behringer R.R., de Crombrugghe B., The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation, Cell., 108: 117-129, 2002
-
(2002)
Cell
, vol.108
, pp. 117-129
-
-
Nakashima, K.1
Zhou, X.2
Kunkel, G.3
Zhang, Z.4
Deng, J.M.5
Behringer, R.R.6
De Crombrugghe, B.7
-
35
-
-
2342476573
-
Regulatory controls for osteoblast growth and differentiation: Role of Runx/Cbfa/AML factors
-
Lian J.B., Javed A., Zaidi S.K., Lengner C., Montecino M., Van Wijnen A.J., Stein J.L., Stein G.S., Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors, Crit. Rev. Eukaryot. Gene Expr., 14: 1-42, 2003
-
(2003)
Crit. Rev. Eukaryot. Gene Expr.
, vol.14
, pp. 1-42
-
-
Lian, J.B.1
Javed, A.2
Zaidi, S.K.3
Lengner, C.4
Montecino, M.5
Van Wijnen, A.J.6
Stein, J.L.7
Stein, G.S.8
-
36
-
-
3242707674
-
Intracellular antibodies as specific reagents for functional ablation: Future therapeutic molecules
-
Lobato M.N., Rabbitts T.H., Intracellular antibodies as specific reagents for functional ablation: future therapeutic molecules, Curr. Mol. Med., 4: 519-528, 2004
-
(2004)
Curr. Mol. Med.
, vol.4
, pp. 519-528
-
-
Lobato, M.N.1
Rabbitts, T.H.2
|