Cell proliferation, apoptosis and apoptosis-related factors in odontogenic keratocysts and in dentigerous cysts

Journal of Oral Pathology and Medicine

Volumn 34, Issue 5, 2005, Pages 280-286

  Kichi, Eisuke ^a   Enokiya, Yasunobu ^a   Muramatsu, Takashi ^a   Hashimoto, Sadamitsu ^a   Inoue, Takashi ^a   Abiko, Yoshihiro ^b   Shimono, Masaki ^a  

^a TOKYO DENTAL COLLEGE   (Japan)

^b HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

Apoptosis; Apoptosis related factors: bcl 2; Cell proliferation; Dentigerous cyst; Ki67; Odontogenic keratocyst; p53

Indexed keywords

KI 67 ANTIGEN; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CYST; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NICK END LABELING; ODONTOGENIC CYST; PRIORITY JOURNAL; TERATOMA;

APOPTOSIS; CELL PROLIFERATION; DENTIGEROUS CYST; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU NICK-END LABELING; KI-67 ANTIGEN; ODONTOGENIC CYSTS; PROTO-ONCOGENE PROTEINS C-BCL-2; STATISTICS, NONPARAMETRIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 17144385512     PISSN: 09042512     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2005.00314.x     Document Type: Article

References (39)

1. Browne RM. The odontogenic keratocyst. Histological features and their correlation with clinical behaviour. Br Dent J 1971; 131: 249-59.
2. Toller PA. Autoradiography of explants from odontogenic cysts. Br Dent J 1971; 131: 57-61.
3. Matthews JB, Mason GI, Browne RM. Epithelial cell markers and proliferating cells in odontogenic jaw cysts. J Pathol 1988; 156: 283-90.
4. Shear M. Cysts of the oral regions, 3rd edn. Oxford: Butterworth- Heinemann, 1992: 4-45.
5. Li TJ, Browne RM, Matthews JB. Epithelial cell proliferation in odontogenic keratocysts: a comparative immunocytochemical study of Ki67 in simple, recurrent and basal cell naevus syndrome (BCNS) associated lesions. J Oral Pathol Med 1995; 24: 221-6.
6. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 1. Clinical and early experimental evidence of aggressive behaviour. Oral Oncol 2002; 38: 219-26.
7. Woolgar JA, Rippin JW, Browne RM. A comparative study of the clinical and histological features of recurrent and non-recurrent of ontogenic keratocysts. J Oral Pathol 1987; 16: 124-8.
8. Kondell PA, Wiberg J. Odontogenic keratocysts: a follow up study of 29 cases. Swed Dent J 1988; 12: 57-62.
9. Scharffetter K, Balz-Hwrrmann C, Lagrange W, Koberg W, Mittermayer C. Proliferation kinetics - study of the growth of keratocysts. J Craniomaxillofac Surg 1989; 17: 226-33.
10. Li TJ, Browne RM, Matthews JB. Quantification of PCNA positive cells within odontogenic jaw cyst epithelium. J Oral Pathol Med 1994; 23: 184-9.
11. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 2. Proliferation and genetic studies. Oral Oncol 2002; 38: 323-31.
12. Ogden GR, Chisholm DM, Kiddie RA, Lane DP. p53 protein in odontogenic cysts: Increased expression in some odontogenic keratocysts. J Clin Pathol 1992; 45: 1007-10.
13. Slootweg PJ. p53 protein and Ki-67 reactivity in epithelial odontogenic lesions. An immunohistochemical study. J Oral Pathol Med 1995; 24: 393-7.
14. Lombardi T, Odelll EW, Morgan PR. p53 immunohistochemistry of odontogenic keratocysts in relation to recurrence, basal cell budding and basal-cell naevus syndrome. Arch Oral Biol 1995; 40: 1081-4.
15. Li TJ, Browne RM, Prime SS, Paterson IC, Matthews JB. p53 expression in odontogenic keratocyst epithelium. J Oral Pathol Med 1996; 25: 245-55.
16. El Murtadi A, Grehan D, Toner M, Mc Cartan BE. Proliferating cell nuclear antigen staining in syndrome and nonsyndrome odontogenic keratocysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1996; 81: 217-20.
17. Piattelli A, Fioroni M, Santinelli A, Rubini C. Expression of proliferating cell nuclear antigen in ameloblastomas and odontogenic cysts. Oral Oncol 1998; 34: 408-12.
18. Lo Muzio L, Staibanot S, Pannone G, et al. Expression of cell cycle and apoptosis-related proteins in sporadic odontogenic keratocysts and odontogenic keratocysts associated with the nevoid basal cell carcinoma syndrome. J Dent Res 1999; 78: 1345-53.
19. Kimi K, Kumamoto H, Ooya K, Motegi K. Analysis of apoptosis-related factors and apoptotic cells in lining epithelium of odontogenic keratocysts. Oral Med Pathol 2000; 5: 35-40.
20. Kimi K, Kumamoto H, Ooya K, Motegi K. Immunohistochemical analysis of cell-cycle- and apoptosis-related factors in lining epithelium of odontogenic keratocysts. J Oral Pathol Med 2001; 30: 434-42.
21. Prives C, Hall PA. The p53 pathway. J Pathol 1999; 187: 112-26.
22. Lu QL, Abel P, Foster CS, Lalani EN. Bcl-2: role in epithelial differentiation and oncogenesis. Human Pathol 1996; 27: 102-10.
23. Singh BB, Chandler FW Jr, Whitaker SB, Forbes-Nelson AE. Immunohistochemical evaluation of bcl-2 oncoprotein in oral dysplasia and carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 85: 692-8.
24. Tosios KI, Angelopoulou K, Kapranos N. Immunohistochemical study of bcl-2 protein, Ki-67 antigen and p53 protein in epithelium of glandular odontogenic cysts and dentigerous cysts. J Oral Pathol Med 2000; 29: 139-44.
25. Kumamoto H. Detection of apoptosis-related factors and apoptotic cells in ameloblastomas: analysis by immunohistochemistry and an in situ DNA nick end-labeling method. J Oral Pathol Med 1997; 26: 419-25.
26. Slootweg PJ, De Weger RA. Immunohistochemical demonstration of bcl-2 protein in human tooth germs. Arch Oral Biol 1994; 39: 545-50.
27. Mitsuyasu T, Harada H, Higuchi Y, et al. Immunohistochemical demonstration of bcl-2 protein in ameloblastoma. J Oral Pathol Med 1997; 26: 345-8.
28. Kim DK, Ahn SG, Kim J, Yoon JH. Comparative Ki-67 expression and apoptosis in the odontogenic keratocyst associated with or without an impacted tooth in addition to unilocular and multilocular varieties. Yonsei Med J 2003; 44: 841-6.
29. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501.
30. Haake AR, Polakowska RR. Cell death by apoptosis in epidermal biology. J Invest Dermatol 1993; 101: 107-12.
31. Macall CA, Cohen JJ. Programmed cell death in terminally differentiating keratinocytes: role of endogenous endonuclease. J Invest Dermatol 1991; 97: 111-4.
32. Maruoka Y, Harada H, Mitsuyasu T, et al. Keratinocytes become terminally differentiated in a process involving programmed cell death. Biochem Biophys Res Commun 1997; 238: 886-90.
33. Nylander K, Nilsson P, Mehle C, Roos G. p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck. Br J Cancer 1995; 71: 826-30.
34. Sjogren S, Inganas M, Norberd T, Lindgren A, Nordgren H. The p53 gene in breast cancer: prognostic value of complementary DNA sequencing versus immunohistochemistry. J Natl Cancer Inst 1996; 88: 173-82.
35. Schmitt CA, Lowe SW. Apoptosis and therapy. J Pathol 1999; 187: 127-37.
36. Shibata T, Nakata D, Chiba I, et al. Detection of TP53 mutation in ameloblastoma by the use of a yeast functional assay. J Oral Pathol Med 2002; 31: 534-8.
37. Yokoo K, Noma H, Inoue T, Hashimoto S, Shimono M. Cell proliferation and tumor suppressor gene expression in iodine unstained area surrounding oral squamous cell carcinoma. Int J Oral Maxillofac Surg 2004; 33: 75-83.
38. Joensuu H, Pylkkanen L, Toikkanen S. Bcl-2 protein expression and long-term survival in breast cancer. Am J Pathol 1994; 145: 1191-8.
39. Hellemans P, Van Dam PA, Weyler J, Van Oosterom AT, Buytaert P, Vav Marck E. Prognostic value of bcl-2 expression in invasive breast cancer. Br J Cancer 1995; 72: 354-60.