The aggressive nature of the odontogenic keratocyst: Is it a benign cystic neoplasm? Part 2. Proliferation and genetic studies

Oral Oncology

Volumn 38, Issue 4, 2002, Pages 323-331

  Shear, Mervyn ^a  

^a UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

Cysts; Jaw cysts; Keratocyst; Odontogenic keratocyst; OKC; PCNA, Ki67, p53; Primordial cyst; PTCH

Indexed keywords

CYCLIN D1; CYCLINE; KI 67 ANTIGEN; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN P53;

BASAL CELL NEVUS SYNDROME; BASEMENT MEMBRANE; CELL PROLIFERATION; CHROMOSOME 9Q; CHROMOSOME NOR; DISEASE MARKER; EPIDERMIS; GENE LOSS; GENE MAPPING; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; ODONTOGENIC CYST; ODONTOGENIC KERATOCYST; ODONTOGENIC TUMOR; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SOMATIC CELL; STEM CELL; TERATOMA; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

EID: 0036079610     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1368-8375(01)00066-5     Document Type: Short Survey

References (22)

1. Discrimination of parakeratinised odontogenic keratocysts from other odontogenic and non-odontogenic cyst types by expression of a 38kd cell-surface glycoprotein
2. P53 protein in odontogenic cysts: Increased expression in some odontogenic keratocysts
3. Quantification of PCNA+ cells within odontogenic jaw cyst epithelium
4. Epithelial cell proliferation in odontogenic keratocysts: Immunocytochemical study of Ki67 in simple, recurrent and basal cell naevus syndrome (BCNS)-associated lesions
5. Proliferating cell nuclear antigen staining in syndrome and nonsyndrome odontogenic keratocysts
6. Expression of proliferating cell nuclear antigen in ameloblastomas and odontogenic cysts
7. Cell proliferation markers in the odontogenic keratocyst: Effect of inflammation
8. P53 protein and Ki-67 reactivity in epithelial odontogenic lesions
9. P53 immunohistochemistry of odontogenic keratocysts in relation to recurrence, basal cell budding and basal-cell naevus syndrome
10. P53 expression in odontogenic keratocyst epithelium
11. Location of gene for Gorlin syndrome
12. Expression of cell cycle and apoptosis-related proteins in sporadic odontogenic keratocysts and odontogenic keratocysts associated with the naevoid basal cell carcinoma syndrome
13. A two-hit model for developmental defects in Gorlin Syndrome
14. Investigation of chromosome 9q22.3-q31 DNA marker loss in odontogenic keratocysts
15. Mutation and cancer: Statistical study of retinoblastoma
16. Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome
17. The Gorlin syndrome gene: A tumour suppressor active in basal cell carcinogenesis and embryonic development
18. PTCH gene mutations in odontogenic keratocysts
19. Nevoid basal cell carcinoma syndrome: Molecular biology and new hypotheses
20. Allelic losses in chromosome 9q22.3-31q in odontogenic keratocysts
21. Involvement of PTCH gene in various noninflammatory cysts