Nitric oxide induces apoptosis in mouse C2C12 myoblast cells

Journal of Pharmacological Sciences

Volumn 97, Issue 3, 2005, Pages 369-376

  Lee, Myoung Hwa ^a,b   Jang, Mi Hyeon ^a   Kim, Eun Kyung ^a   Han, Sang Wan ^c   Cho, Seong Yeon ^a,b   Kim, Chang Ju ^a  

^a Kyung Hee University Hospital   (South Korea)

^b SKY Sports Medicine Lab   (South Korea)

^c Gwangju Health College University   (South Korea)

Author keywords

Apoptosis; C2C12 myoblast cell; Nitric oxide

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4',6 DIAMIDINO 2 PHENYLINDOLE; CASPASE 3; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; PROTEIN BAX; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FLOW CYTOMETRY; MOUSE; MYOBLAST; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 17144374462     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.FPJ04017X     Document Type: Article

References (32)

1. Reid MB. Role of nitric oxide in skeletal muscle: synthesis, distribution and functional importance. Acta Physiol Scand. 1998;162:401-409.
2. Lawler JM, Song W. Specificity of antioxidant enzyme inhibition in skeletal muscle to reactive nitrogen species donors. Biochem Biophys Res Commun. 2002;294:1093-1100.
3. Zhuang W, Eby JC, Cheong M, Mohapatra PK, Bredt DS, Disatnik MH, et al. The susceptibility of muscle cells to oxidative stress is independent of nitric oxide synthase expression. Muscle Nerve. 2001;24:502-511.
4. Kerr JFR, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer. 1972;26:239-257.
5. Woodle ES, Kulkarni S. Programmed cell death. Transplantation. 1998;66:681-691.
6. Johnson EM Jr, Greenlund LJ, Akins PT, Hsu CY. Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischemic brain injury. J Neurotrauma. 1995;12: 843-852.
7. Smith CD, Carney JM, Starke-Reed PE, Oliver CN, Stadtman ER, Floyd RA, et al. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA. 1991;88:10540-10543.
8. Lowe SW, Ruley HE. Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev. 1993;7:535-545.
9. Xiang H, Kinoshita Y, Knudson CM, Korsmeyer SJ, Schwartzkroin PA, Morrison RS. Bax involvement in p53-mediated neuronal cell death. J Neurosci. 1998;18:1363-1373.
10. Budihardjo I, Oliver H, Lutter M, Luo X, Wang X. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol. 1999;15:269-290.
11. Korsmeyer SJ. BCL-2 gene family and the regulation of programmed cell death. Cancer Res. 1999;59:1693s-1700s.
12. Cohen GM. Caspases: the executioners of apoptosis. Biochem J. 1997;326:1-16.
13. Georges B, Galland S, Rigault C, Le Borgne F, Demarquoy J. Beneficial effects of L-carnitine in myoblastic C2C12 cells. Interaction with zidovudine. Biochem Pharmacol. 2003;65: 1483-1488.
14. Jang MH, Shin MC, Lim S, Han SM, Park HJ, Shin I, et al. Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299. J Pharmacol Sci. 2003;91:95-104.
15. Yim SV, Kim KH, Kim CJ, Chung JH. Serotonin induces apoptosis in PGT-beta pineal gland tumor cells. Jpn J Pharmacol. 2000;84:71-74.
16. Kim EH, Jang MH, Shin MC, Shin MS, Kim CJ. Protective effect of aqueous extract of Ginseng radix against 1-methyl-4-phenylpyridinium-induced apoptosis in PC12 cells. Biol Pharm Bull. 2003;26:1668-1673.
17. Brune B, von Knethen A, Sandau K. Nitric oxide and its role in apoptosis. Eur J Pharmacol. 1998;351:261-272.
18. Kroncke KD, Fehsel K, Kolb-Bachofen V. Nitric oxide: cytotoxicity versus cytoprotection - how, why, when, and where? Nitric Oxide. 1997;1:107-120.
19. Dimmeler S, Haendeler J, Nehls M, Zeiher AM. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases. J Exp Med. 1997;185:601-607.
20. Yoshioka Y, Yamamuro A, Maeda S. Nitric oxide at a low concentration protects murine macrophage RAW264 cells against nitric oxide-induced death via cGMP signaling pathway. Br J Pharmacol. 2003;139:28-34.
21. Estevez AG, Spear N, Manuel SM, Radi R, Henderson CE, Barbeito L, et al. Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. J Neurosci. 1998;18:923-931.
22. Yoo YM, Yim SV, Kim SS, Jang HY, Lea HZ, Hwang GC, et al. Melatonin suppresses NO-induced apoptosis via induction of Bcl-2 expression in PGT-beta immortalized pineal cells. J Pineal Res. 2002;33:146-150.
23. Yuyama K, Yamamoto H, Nishizaki I, Kato T, Sora I, Yamamoto T. Caspase-independent cell death by low concentrations of nitric oxide in PC 12 cells: involvement of cytochrome C oxidase inhibition and the production of reactive oxygen species in mitochondria. J Neurosci Res. 2003;73:351-363.
24. Silveira LR, Pereira-Da-Silva L, Juel C, Hellsten Y. Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions. Free Radic Biol Med. 2003;35:455-464.
25. Moncada S, Higgs A. The L-arginine-nitric oxide pathway. N Engl J Med. 1993;329:2002-2012.
26. Baron P, Galimberti D, Meda L, Prat E, Scarpini E, Conti G, et al. Synergistic effect of beta-amyloid protein and interferon gamma on nitric oxide production by C2C12 muscle cells. Brain. 2000;123:374-379.
27. Eastman A, Barry MA. The origins of DNA breaks: a consequence of DNA damage, DNA repair, or apoptosis? Cancer Invest. 1992;10:229-240.
28. Ghatan S, Lamer S, Kinoshita Y, Hetman M, Patel L, Xia Z, et al. p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. J Cell Biol. 2000;150:335-347.
29. Bal-Price A, Brown GC. Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria. J Neurochem. 2000;75:1455-1464.
30. Baud O, Li J, Zhang Y, Neve RL, Volpe JJ, Rosenberg PA. Nitric oxide-induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis-inducing factor translocation. Eur J Neurosci. 2004;20:1713-1726.
31. Matsuzaki H, Tamatani M, Mitsuda N, Namikawa K, Kiyama H, Miyake S, et al. Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons. J Neurochem. 1999;73:2037-2046.
32. Uchiyama T, Otani H, Okada T, Ninomiya H, Kido M, Imamura H, et al. Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes. J Mol Cell Cardiol. 2002;34:1049-1061.