SCOPUS 정보 검색 플랫폼

Volumn 24, Issue 2, 2005, Pages 240-253

4D-QSAR models of HOE/BAY-793 analogues as HIV-1 protease inhibitors

(4) Ferreira Da Cunha, Elaine Fontes a Girão Albuquerque, Magaly a Ceva Antunes, Octavio Augusto a Bicca De Alencastro, Ricardo a

a FEDERAL UNIVERSITY OF RIO DE JANEIRO (Brazil)

Author keywords

4D QSAR; C2 symmetric diol; HIV protease

Indexed keywords

COMPUTATIONAL CHEMISTRY; CONFORMATIONS; GENETIC ALGORITHMS; GEOMETRY; LEAST SQUARES APPROXIMATIONS; MOLECULAR DYNAMICS; MOLECULAR GRAPHICS;

4D-QSAR; AMINO-ACIDS; C2-SYMMETRIC DIOL; HIV-1 PROTEASE; HIV-1 PROTEASE INHIBITORS; HIV-PROTEASE; HOMODIMERS; QSAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; SYMMETRICS;

CELL CULTURE;

AMPRENAVIR; ANTIVIRUS AGENT; ASPARTIC ACID; BAY 793; CARBONYL DERIVATIVE; DIAMINODIOL INHIBITOR; DIMER; GLYCINE; HOE 793; HYDROXYL GROUP; INDINAVIR; LOPINAVIR; MONOMER; NELFINAVIR; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING KINETICS; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG CONFORMATION; DRUG POTENCY; DRUG RECEPTOR BINDING; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME STRUCTURE; EVALUATION; GENETIC ALGORITHM; GEOMETRY; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; IC 50; IN VITRO STUDY; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; SIMULATION; STRUCTURE ANALYSIS; TECHNIQUE; TEMPERATURE DEPENDENCE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 17144374002 PISSN: 1611020X EISSN: None Source Type: Journal
DOI: 10.1002/qsar.200430893 Document Type: Article

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