Membranes, ions, and clocks: Testing the Njus-Sulzman-Hastings model of the circadian oscillator

Methods in Enzymology

Volumn 393, Issue , 2005, Pages 682-693

  Nitabach, Michael N ^a   Holmes, Todd C ^b   Blau, Justin ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL;

AUTOREGULATION; CELL MEMBRANE; CIRCADIAN RHYTHM; ION CURRENT; ION TRANSPORT; MOLECULAR GENETICS; NEGATIVE FEEDBACK; NONHUMAN; OSCILLATOR; PRIORITY JOURNAL; REVIEW; SUPRACHIASMATIC NUCLEUS; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

EID: 16844382553     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(05)93036-X     Document Type: Article

References (55)

1. Akasu T., Shoji S., Hasuo H. Inward rectifier and low-threshold calcium currents contribute to the spontaneous firing mechanism in neurons of the rat suprachiasmatic nucleus. Pflug. Arch. 425:1993;109-116
2. Baines R.A., Uhler J.P., Thompson A., Sweeney S.T., Bate M. Altered electrical properties in Drosophila neurons developing without synaptic transmission. J. Neurosci. 21:2001;1523-1531
3. Blanchardon E., Grima B., Klarsfeld A., Chelot E., Hardin P.E., Preat T., Rouyer F. Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eclosion by targeted genetic ablation and PERIOD protein overexpression. Eur. J. Neurosci. 13:2001;871-888
4. Block G.D. In vivo recording of the ocular circadian rhythm in Aplysia. Brain Res. 222:1981;138-143
5. Block G.D., Wallace S.F. Localization of a circadian pacemaker in the eye of a mollusc. Bulla. Science. 217:1982;155-157
6. Blumenthal E.M., Block G.D., Eskin A. Cellular and molecular analysis of molluscan circadian pacemakers. "Handbook of Behavioral Neurobiology: Circadian Clocks." 2001;Plenum, New York
7. Bos N.P., Mirmiran M. Circadian rhythms in spontaneous neuronal discharges of the cultured suprachiasmatic nucleus. Brain Res. 511:1990;158-162
8. Brand A.H., Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:1993;401-415
9. Cloues R.K., Sather W.A. Afterhyperpolarization regulates firing rate in neurons of the suprachiasmatic nucleus. J. Neurosci. 23:2003;1593-1604
10. Colwell C.S. Circadian modulation of calcium levels in cells in the suprachiasmatic nucleus. Eur. J. Neurosci. 12:2000;571-576
11. de Jeu M., Hermes M., Pennartz C. Circadian modulation of membrane properties in slices of rat suprachiasmatic nucleus. Neuroreport. 9:1998;3725-3729
12. de Jeu M.T., Pennartz C.M. Functional characterization of the H-current in SCN neurons in subjective day and night: A whole-cell patch-clamp study in acutely prepared brain slices. Brain Res. 767:1997;72-80
13. Earnest D.J., Digiorgio S.M., Sladek C.D. Effects of tetrodotoxin on the circadian pacemaker mechanism in suprachiasmatic explants in vitro. Brain Res. Bull. 26:1991;677-682
14. Frisch B., Hardin P.E., Hamblen-Coyle M.J., Rosbash M., Hall J.C. A promoterless period gene mediates behavioral rhythmicity and cyclical per expression in a restricted subset of the Drosophila nervous system. Neuron. 12:1994;555-570
15. Gillette M.U., Reppert S.M. The hypothalamic suprachiasmatic nuclei: Circadian patterns of vasopressin secretion and neuronal activity in vitro. Brain Res. Bull. 19:1987;135-139
16. Goldstein S.A., Price L.A., Rosenthal D.N., Pausch M.H. ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA. 93:1996;13256-13261
17. Green D.J., Gillette R. Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice. Brain Res. 245:1982;198-200
18. Groos G., Hendriks J. Circadian rhythms in electrical discharge of rat suprachiasmatic neurones recorded in vitro. Neurosci. Lett. 34:1982;283-288
19. Herzog E.D., Geusz M.E., Khalsa S.B., Straume M., Block G.D. Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates. Brain Res. 757:1997;285-290
20. 2+ in single suprachiasmatic nucleus neurons. Neuron. 38:2003;253-263
21. Jacklet J.W. Circadian rhythm of optic nerve impulses recorded in darkness from isolated eye of Aplysia. Science. 164:1969;562-563
22. Jobst E.E., Allen C.N. Calbindin neurons in the hamster suprachiasmatic nucleus do not exhibit a circadian variation in spontaneous firing rate. Eur. J. Neurosci. 16:2002;2469-2474
23. Kaneko M., Park J.H., Cheng Y., Hardin P.E., Hall J.C. Disruption of synaptic transmission or clock-gene-product oscillations in circadian pacemaker cells of Drosophila cause abnormal behavioral rhythms. J. Neurobiol. 43:2000;207-233
24. Khalsa S.B., Michel S., Block G.D. The role of extracellular sodium in the mechanism of a neuronal in vitro circadian pacemaker. Chronobiol. Int. 14:1997;1-8
25. Khalsa S.B., Ralph M.R., Block G.D. Chloride conductance contributes to period determination of a neuronal circadian pacemaker. Brain Res. 520:1990;166-169
26. Khalsa S.B., Ralph M.R., Block G.D. The role of extracellular calcium in generating and in phase-shifting the Bulla ocular circadian rhythm. J. Biol. Rhythms. 8:1993;125-139
27. Kononenko N.I., Shao L.R., Dudek F.E. Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons. J. Neurophysiol. 91:2004;710-718
28. Lee H.S., Billings H.J., Lehman M.N. The suprachiasmatic nucleus: A clock of multiple components. J. Biol. Rhythms. 18:2003;435-449
29. McMahon D.G., Block G.D. The Bulla ocular circadian pacemaker. II. Chronic changes in membrane potential lengthen free running period. J. Comp. Physiol. A. 161:1987;347-354
30. Michel S., Geusz M.E., Zaritsky J.J., Block G.D. Circadian rhythm in membrane conductance expressed in isolated neurons. Science. 259:1993;239-241
31. Michel S., Manivannan K., Zaritsky J.J., Block G.D. A delayed rectifier current is modulated by the circadian pacemaker in Bulla. J. Biol. Rhythms. 14:1999;141-150
32. Nitabach M.N., Blau J., Holmes T.C. Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock. Cell. 109:2002;485-495
33. Nitabach M.N., Blau J., Holmes T.C. Program No. 284.11. 2003 Abstract Viewer/Itinerary Planner. Pacemaker membrane excitability controls the period and coherence of the free running Drosophila circadian oscillator. 2003;Society for Neuroscience, Washington, DC., 2003.
34. Nitabach M.N., Sheeba V., Vera D.A., Blau J., Holmes T.C. Membrane electrical excitability is necessary for the free-running larval Drosophila circadian clock. J. Neurobiol. 6:2005;1-13
35. Njus D., Gooch V.D., Mergenhagen D., Sulzman F., Hastings J.W. Membranes and molecules in circadian systems. Fed. Proc. 35:1976;2353-2357
36. Njus D., Sulzman F.M., Hastings J.W. Membrane model for the circadian clock. Nature. 248:1974;116-120
37. Park J.H., Helfrich-Forster C., Lee G., Liu L., Rosbash M., Hall J.C. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila. Proc. Natl. Acad. Sci. USA. 97:2000;3608-3613
38. Pennartz C.M., de Jeu M.T., Bos N.P., Schaap J., Geurtsen A.M. Diurnal modulation of pacemaker potentials and calcium current in the mammalian circadian clock. Nature. 416:2002;286-290
39. Quintero J.E., Kuhlman S.J., McMahon D.G. The biological clock nucleus: A multiphasic oscillator network regulated by light. J. Neurosci. 23:2003;8070-8076
40. Ralph M.R., Block G.D. Circadian and light-induced conductance changes in putative pacemaker cells of Bulla gouldiana. J. Comp. Physiol. A. 166:1990;589-595
41. Renn S.C., Park J.H., Rosbash M., Hall J.C., Taghert P.H. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. Cell. 99:1999;791-802
42. Roberts M.H., Block G.D. Mutual coupling between the ocular circadian pacemakers of Bulla gouldiana. Science. 221:1983;87-89
43. Schwartz W.J., Gross R.A., Morton M.T. The suprachiasmatic nuclei contain a tetrodotoxin-resistant circadian pacemaker. Proc. Natl. Acad. Sci. USA. 84:1987;1694-1698
44. Shibata S., Moore R.Y. Tetrodotoxin does not affect circadian rhythms in neuronal activity and metabolism in rodent suprachiasmatic nucleus in vitro. Brain Res. 606:1993;259-266
45. Shibata S., Oomura Y., Kita H., Hattori K. Circadian rhythmic changes of neuronal activity in the suprachiasmatic nucleus of the rat hypothalamic slice. Brain Res. 247:1982;154-158
46. Shimura M., Akaike N., Harata N. Circadian rhythm in intracellular Cl(-) activity of acutely dissociated neurons of suprachiasmatic nucleus. Am. J. Physiol. Cell. Physiol. 282:2002;C366-C373
47. Silver R., Sookhoo A.I., LeSauter J., Stevens P., Jansen H.T., Lehman M.N. Multiple regulatory elements result in regional specificity in circadian rhythms of neuropeptide expression in mouse SCN. Neuroreport. 10:1999;3165-3174
48. Stanewsky R., Kaneko M., Emery P., Beretta B., Wager-Smith K., Kay S.A., Rosbash M., Hall J.C. The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila. Cell. 95:1998;681-692
49. Teshima K., Kim S.H., Allen C.N. Characterization of an apamin-sensitive potassium current in suprachiasmatic nucleus neurons. Neuroscience. 120:2003;65-73
50. van den Pol A.N., Finkbeiner S.M., Cornell-Bell A.H. Calcium excitability and oscillations in suprachiasmatic nucleus neurons and glia in vitro. J. Neurosci. 12:1992;2648-2664
51. Walsh I.B., van den Berg R.J., Rietveld W.J. Ionic currents in cultured rat suprachiasmatic neurons. Neuroscience. 69:1995;915-929
52. Welsh D.K., Logothetis D.E., Meister M., Reppert S.M. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron. 14:1995;697-706
53. Yamaguchi S., Isejima H., Matsuo T., Okura R., Yagita K., Kobayashi M., Okamura H. Synchronization of cellular clocks in the suprachiasmatic nucleus. Science. 302:2003;1408-1412
54. 2+ oscillation in cultured hypothalamus: Similarity to the mammalian circadian pacemaker. Neuroreport. 6:1995;1306-1308
55. Zilberberg N., Ilan N., Gonzalez-Colaso R., Goldstein S.A. Opening and closing of KCNK0 potassium leak channels is tightly regulated. J. Gen. Physiol. 116:2000;721-734