The role of extracellular sodium in the mechanism of a neuronal in vitro circadian pacemaker

Chronobiology International

Volumn 14, Issue 1, 1997, Pages 1-8

  Khalsa, Sat Bir S ^a,b   Michel, Stephan ^a,c   Block, Gene D ^a,d  

^a Department of Medicine   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Bulla; mollusc; oscillator; rhythm

Indexed keywords

MAGNESIUM; SODIUM;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; MOLLUSC; NONHUMAN; PACEMAKER NERVE CELL; PH; REGULATORY MECHANISM; RETINA NERVE CELL;

ANIMALIA; BULLA; MOLLUSCA;

EID: 0030998025     PISSN: 07420528     EISSN: None     Source Type: Journal    
DOI: 10.3109/07420529709040536     Document Type: Article

References (21)

1. Block GD, Khalsa SBS, McMahon DG, Michel S, Geusz M. Biological clocks in the retina: cellular mechanisms of biological timekeeping. Int Rev Cytol 1993; 146: 83-144.
2. Jacklet JW. Circadian neuronal oscillators. In: Jacklet JW, ed. Neuronal and cellular oscillators. New York: Marcel Dekker, 1989: 483-527.
3. Jacklet JW. Neural organization and cellular mechanisms of circadian pacemakers. Int Rev Cytol 1984; 89:251-94.
4. Block GD, Wallace S. Localization of a circadian pacemaker in the eye of a mollusc, Bulla. Science 1982; 217:155-7.
5. McMahon DG, Wallace SF, Block GD. Cellular analysis of the Bulla ocular circadian pacemaker system. II. Neurophysiological basis of circadian rhythmicity. J Comp Physiol 1984; 155:379-85.
6. Ralph MR, Block GD. Circadian and light-induced conductance changes in putative pacemaker cells of Bulla gouldiana. J Comp Physiol 1990; 166:589-95.
7. Michel S, Geusz ME, Zaritsky JJ, Block GD. Circadian rhythm in membrane conductance expressed in isolated neurons. Science 1993; 259:239-41.
8. Michel S, Manivannan K, Zaritsky JJ, Block GD. Whole cell currents in cultured circadian pacemaker neurons of Bulla. Soc Neurosci Abstr 1993; 19:1616.
9. McMahon DG, Block GD. The Bulla ocular circadian pacemaker. I. Pacemaker membrane potential regulates phase through a calcium dependent mechanism. J Comp Physiol 1987; 161:335-46.
10. Khalsa SBS, Block GD. Calcium channels mediate phase shifts of the Bulla circadian pacemaker. J Comp Physiol 1988; 164:194-206.
11. Khalsa SBS, Block GD. Calcium in phase control of the Bulla circadian pacemaker. Brain Res 1990; 506:40-5.
12. McMahon DG, Block GD. The Bulla ocular circadian pacemaker. II. Chronic changes in membrane potential lengthen free running period. J Comp Physiol 1987; 161:347-54.
13. Khalsa SBS, Ralph MR, Block GD. The role of extracellular calcium in generating and in phase-shifting the Bulla ocular circadian rhythm. J Biol Rhythms 1993; 8: 125-39.
14. Khalsa SBS, Ralph MR, Block GD. Chloride conductance contributes to period determination of a neuronal circadian pacemaker. Brain Res 1990; 520:166-9.
15. Khalsa SBS, Ralph MR, Block GD. Does low intracellular pH stop the motion of the Bulla circadian pacemaker? J Neurosci 1991; 11:2672-9.
16. Pittendrigh CS. Circadian rhythms and the circadian organization of living systems. Cold Spring Harbor Symp Quant Biol 1960; 25:159-84.
17. Roos A, Boron WF. Intracellular pH. Physiol Rev 1981; 61:296-434.
18. Boron WF, Russell JM. Stoichiometry and ion dependencies of the intracellular-pH-regulating mechanism in squid giant axons. J Gen Physiol 1983; 81:373-99.
19. Thomas RC. The role of bicarbonate chloride and sodium ions in the regulation of intracellular pH in snail neurones. J Physiol 1977; 273:317-38.
20. Thomas RC. Snail neuron intracellular pH regulation. In: Nuccitelli R, Deamer DW, eds. Intracellular pH: its measurement, regulation and utilization in cellular functions. New York: Alan R Liss, 1982: 189-204.
21. Rensing L, Hardeland R. The cellular mechanism of circadian rhythms - a view on evidence, hypotheses and problems. Chronobiol Int 1990; 7:353-70.