Membrane electrical excitability is necessary for the free-running larval Drosophila circadian clock

Journal of Neurobiology

Volumn 62, Issue 1, 2005, Pages 1-13

  Nitabach, Michael N ^a,b   Sheeba, Vasu ^a   Vera, David A ^a   Blau, Justin ^a   Holmes, Tod C ^a  

^a NEW YORK UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Circadian clock; Development; Drosophila melanogaster; Ion channel; Membrane activity

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL;

ARTICLE; CELL MEMBRANE DEPOLARIZATION; CIRCADIAN RHYTHM; DARK ADAPTATION; DROSOPHILA MELANOGASTER; GENE EXPRESSION; LARVA; MEMBRANE DEPOLARIZATION; MEMBRANE ELECTROPHYSIOLOGY; NONHUMAN; OSCILLATORY POTENTIAL; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION;

ANIMALS; BIOLOGICAL CLOCKS; CELL MEMBRANE; CIRCADIAN RHYTHM; DARKNESS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEEDBACK; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LARVA; MEMBRANE POTENTIALS; NERVOUS SYSTEM; NEURAL PATHWAYS; NEURONS; NUCLEAR PROTEINS; PHOTIC STIMULATION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; SYNAPTIC TRANSMISSION;

EID: 10444290712     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.20053     Document Type: Article

References (51)

1. Baines RA, Uhler JP, Thompson A, Sweeney ST, Bate M. 2001. Altered electrical properties in Drosophila neurons developing without synaptic transmission. J Neurosci 21:1523-1531.
2. Barish ME. 1998. Intracellular calcium regulation of channel and receptor expression in the plasmalemma: potential sites of sensitivity along the pathways linking transcription, translation, and insertion. J Neurobiol 37:146-157.
3. Blanchardon E, Grima B, Klarsfeld A, Chelot E, Hardin PE, Preat T, Rouyer F. 2001. Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eclosion by targeted genetic ablation and PERIOD protein overexpression. Eur J Neurosci 13:871-888.
4. Blau J, Young MW. 1999. Cycling vrille expression is required for a functional Drosophila clock. Cell 99:661-671.
5. Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
6. Delisle MB, Carpenter S. 1984. Neurofibrillary axonal swellings and amyotrophic lateral sclerosis. J Neurol Sci 63:241-250.
7. Emery P, So WV, Kaneko M, Hall JC, Rosbash M. 1998. CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity. Cell 95:669-679.
8. Emery P, Stanewsky R, Helfrich-Förster C, Emery-Le M, Hall JC, Rosbash M. 2000. Drosophila CRY is a deep brain circadian photoreceptor. Neuron 26:493-504.
9. Gold BG. 1987. The pathophysiology of proximal neurofilamentous giant axonal swellings: implications for the pathogenesis of amyotrophic lateral sclerosis. Toxicology 46:125-139.
10. Helfrich-Förster C. 1997. Development of pigment-dispersing hormone-immunoreactive neurons in the nervous system of Drosophila melanogaster. J Comp Neurol 380:335-354.
11. Helfrich-Förster C, Winter C, Hofbauer A, Hall JC, Stanewsky R. 2001. The circadian clock of fruit flies is blind after elimination of all known photoreceptors. Neuron 30:249-261.
12. Holmes TC. 2002. Ion channel-directed therapies in autonomie neurons: a view from the bench. Clin Auton Res 12:59-65
13. Holmes TC, Berman K, Swartz JE, Dagan D, Levitan IB. 1997. Expression of voltage-gated potassium channels decreases cellular protein tyrosine phosphorylation. J Neurosci 17:8964-8974.
14. Ikeda M, Sugiyama T, Wallace CS, Gompf HS, Yoshioka T, Miyawaki A, Allen CN. 2003. Circadian dynamics of cytosolic and nuclear Ca2+ in single suprachiasmatic nucleus neurons. Neuron 38:253-263.
15. Johns DC, Marx R, Mains RE, O'Rourke B, Marban E. 1999. Inducible genetic suppression of neuronal excitability. J Neurosci 19:1691-1697.
16. Kaneko M, Hamblen MJ, Hall JC. 2000a. Involvement of the period gene in developmental time-memory: effect of the perShort mutation on phase shifts induced by light pulses delivered to Drosophila larvae. J Biol Rhythms 15:13-30.
17. Kaneko M, Helfrich-Förster C, Hall JC. 1997. Spatial and temporal expression of the period and timeless genes in the developing nervous system of Drosophila: newly identified pacemaker candidates and novel features of clock gene product cycling. J Neurosci 17:6745-6760.
18. Kaneko M, Park JH, Cheng Y, Hardin PE, Hall JC. 2000b. Disruption of synaptic transmission or clock-gene-product oscillations in circadian pacemaker cells of Drosophila cause abnormal behavioral rhythms. J Neurobiol 43:207-233.
19. Khalsa SB, Michel S, Block GD. 1993. The effects of lithium on a neuronal in vitro circadian pacemaker. Chronobiol Int 10:321-330.
20. Khalsa SB, Ralph MR, Block GD. 1990. Chloride conductance contributes to period determination of a neuronal circadian pacemaker. Brain Res 520:166-169.
21. Ko GY, Ko ML, Dryer SE. 2001. Circadian regulation of cGMP-gated cationic channels of chick retinal cones. Erk MAP Kinase and Ca2+/calmodulin-dependent protein kinase II. Neuron 29:255-266.
22. Ko GY, Ko ML, Dryer SE. 2004. Circadian regulation of cGMP-gated channels of vertebrate cone photoreceptors: role of cAMP and Ras. J Neurosci. 24:1296-1304.
23. Michel S, Geusz ME, Zaritsky JJ, Block GD. 1993. Circadian rhythm in membrane conductance expressed in isolated neurons. Science 259:239-241.
24. Michel S, Khalsa SB, Block GD. 1992. Phase shifting of the circadian rhythm in the eye of Bulla by inhibition of chloride conductance. Neurosci Lett 146:219-222.
25. Michel S, Manivannan K, Zaritsky JJ, Block GD. 1999. A delayed rectifier current is modulated by the circadian pacemaker in Bulla. J Biol Rhythms 14:141-150.
26. Nadeau H, McKinney S, Anderson DJ, Lester HA. 2000. ROMK1 (Kir1.1) causes apoptosis and chronic silencing of hippocampal neurons. J Neurophysiol 84:1062-1075.
27. Nash HA, Scott RL, Lear BC, Allada R. 2002. An unusual cation channel mediates photic control of locomotion in Drosophila. Curr Biol 2002 12:2152-2158.
28. Nitabach MN, Blau J, Holmes TC. 2002. Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock. Cell 109:485-495.
29. Park JH, Helfrich-Förster C, Lee G, Liu L, Rosbash M, Hall JC. 2000. Differential regulation of circadian pacemaker output by separate clock genes in Drosophila. Proc Natl Acad Sci USA 97:3608-3613.
30. Pennartz CM, de Jeu MT, Bos NP, Schaap J, Geurtsen AM. 2002. Diurnal modulation of pacemaker potentials and calcium current in the mammalian circadian clock. Nature 416:286-290.
31. Price JL, Blau J, Rothenfluh A, Abodeely M, Kloss B, Young MW. 1998. Double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation. Cell 94:83-95.
32. Ramon y Cajal S. 1928. Degeneration and Regeneration of the nervous system. New York: Hafner.
33. Renn SC, Park JH, Rosbash M, Hall JC, Taghert PH. 1999. A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila. Cell 99:791-802.
34. Reppert SM, Weaver DR. 2000. Comparing clockworks: mouse versus fly. J Biol Rhythms 15:357-364.
35. Schwartz WJ, Gross RA, Morton MT. 1987. The suprachiasmatic nuclei contain a tetrodotoxin-resistant circadian pacemaker. Proc Natl Acad Sci USA 84:1694-1698.
36. Sehgal A, Price J, Young MW. 1992. Ontogeny of a biological clock in Drosophila melanogaster. Proc Natl Acad Sci USA 89:1423-1427.
37. Slimko EM, McKinney S, Anderson DJ, Davidson N, Lester HA. 2002. Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligandgated chloride channels. J Neurosci 22:7373-7379.
38. Sokalove G, Bushell W. 1978. The chi square periodogram: It's utility for analysis of circadian rhythms. J Theor Biol 72:131-160.
39. Spitzer NC, Ribera AB. 1998. Development of electrical excitability in embryonic neurons: mechanisms and roles. J Neurobiol 37:190-197.
40. Stanewsky R, Kaneko M, Emery P, Beretta B, Wager-Smith K, Kay SA, Rosbash M, Hall JC. 1998. The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila. Cell 95:681-692.
41. Svoboda KR, Linares AE, Ribera AB. 2001. Activity regulates programmed cell death of zebrafish Rohon-Beard neurons. Development 128:3511-3520.
42. Sweeney ST, Broadie K, Keane J, Niemann H, O'Kane CJ. 1995. Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects. Neuron 14:341-351.
43. Turrigiano GG, Nelson SB. 2004. Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci. 5:97-107.
44. van den Pol AN, Obrietan K. 2002. Short circuiting the circadian clock. Nat Neurosci 5:616-618.
45. Welsh DK, Logothetis DE, Meister M, Reppert SM. 1995. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14:697-706.
46. West AE, Chen WG, Dalva MB, Dolmetsch RE, Kornhauser JM, Shaywitz AJ, Takasu MA, Tao X, Greenberg ME. 2001. Calcium regulation of neuronal gene expression. Proc Natl Acad Sci USA 98:11024-11031.
47. White BH, Osterwalder TP, Yoon KS, Joiner WJ, Whim MD, Kaczmarek LK, Keshishian H. 2001. Targeted attenuation of electrical activity in Drosophila using a genetically modified K+ channel. Neuron 31:699-711.
48. Williams JA, Sehgal A. 2001. Molecular components of the circadian system in Drosophila. Annu Rev Physiol 63:729-755.
49. Young MW. 1998. The molecular control of circadian behavioral rhythms and their entrainment in Drosophila. Annu Rev Biochem 67:135-152.
50. Young MW, Kay SA. 2001. Time zones: a comparative genetics of circadian clocks. Nat Rev Genet 2:702-715.
51. Zilberberg N, Ilan N, Gonzalez-Colaso R, Goldstein SA. 2000. Opening and closing of KCNKO potassium leak channels is tightly regulated. J Gen Physiol 116:721-734.