The effect of a newly synthesized indazole compound, TAS-3-124, on experimental autoimmune disease

Biological and Pharmaceutical Bulletin

Volumn 27, Issue 8, 2004, Pages 1218-1223

  Akabane, Hirotomo ^a   Miyagawa, Naoki ^a   Nii, Hiroaki ^a   Inami, Yoshihiro ^a   Togawa, Michinori ^b   Tanaka, Hiroyuki ^a   Inagaki, Naoki ^a   Nagai, Hiroichi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Collagen induced arthritis (CIA); Experimental autoimmune encephalomyelitis (EAE); IL 6; Interleukin (IL) 1 ; TAS 3 124; Tumor necrosis factor (TNF)

Indexed keywords

6 ACETOAMIDO 1 ACETYL 1 INDAZOLE; COLLAGEN TYPE 2; CYTOKINE; INDAZOLE DERIVATIVE; INTERLEUKIN 1; INTERLEUKIN 6; MESSENGER RNA; MYELIN BASIC PROTEIN; TAS 3 124; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 6-ACETOAMIDO-1-ACETYL-1-INDAZOLE; ACETAMIDE DERIVATIVE; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; BONE DESTRUCTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DRUG EFFICACY; DRUG SYNTHESIS; FEMALE; FORELIMB; HINDLIMB; HISTOPATHOLOGY; KNEE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PERIPHERAL EDEMA; PROBABILITY; PROTEIN EXPRESSION; T LYMPHOCYTE; ALLERGIC ENCEPHALOMYELITIS; ANIMAL; BIOSYNTHESIS; NUCLEOTIDE SEQUENCE; RAT;

ACETAMIDES; ANIMALS; ARTHRITIS, EXPERIMENTAL; BASE SEQUENCE; CYTOKINES; DNA PRIMERS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HYPERSENSITIVITY, DELAYED; INDAZOLES; MALE; MICE; RATS;

EID: 16644383824     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.27.1218     Document Type: Article

References (31)

1. Feldmann M., Miotla J., Paleolog E., Williams R., Malfait A. M., Taylor P., Brennan F. M., Maini R. N., Ann. Rheum. Dis., 59 (Suppl. 1), i119-122 (2000).
2. Haraoui B., Strand V., Keystone E., Curr. Pharm. Biotechnol., 1, 217-233 (2000).
3. Pascual M., Nieto A., Mataran L., Balsa A., Pascual-Salcedo D., Martin J., Genes. Immun., 1, 338-340 (2000).
4. Fernandez-Botran R., Expert. Opin. Investig. Drugs, 9, 497-514 (2000).
5. Paleolog E. M., Hunt M., Elliott M. J., Feldmann M., Maini R. N., Woody J. N., Arthritis. Rheum., 39, 1082-1091 (1996).
6. Gerritsen M. E., Kelley K. A., Ligon G., Perry C. A., Shen C. P., Szczepanski A., Carley W. W., Arthritis. Rheum., 36, 593-602 (1993).
7. Standiford T. J., Kunkel S. L., Rolfe M. W., Evanoff H. L., Allen R. M., Strieter R. M., Am. J. Respir. Cell. Mol. Biol., 6, 75-81 (1992).
8. Conlon K., Lloyd A., Chattopadhyay U., Lukacs N., Kunkel S., Schall T., Taub D., Morimoto C., Osborne J., Oppenheim J., Young H., Kelvin D., Ortaldo J., Eur. J. Immunol., 25, 751-756 (1995).
9. Nakajima Y., Sato K., Morita H., Torikai S., Hidano A., Nishioka K., Kashiwazaki S., J. Rheumatol., 19, 1643-1646 (1992).
10. Bucala R., Ritchlin C., Winchester R., Cerami A., J. Exp. Med., 173, 569-574 (1991).
11. Chu C. Q., Field M., Allamd S., Abney E., Feldmann M., Maini R. N., Br. J. Rheumatol., 31, 653-661 (1992).
12. Aigner T., Vornehm S. I., Belke J., von der Mark K., Kirchner T., Verh. Dtsch. Ges. Pathol., 80, 282-287 (1996).
13. Miller V. E., Rogers K., Muirden K. D., Rheumatol Int., 13, 77-82 (1993).
14. McGuire-Goldring M. B., Meats J. E., Wood D. D., Ihrie E. J., Ebsworth N. M., Russell R. G., Arthritis. Rheum., 27, 654-662 (1984).
15. Ollivierre F., Gubler U., Towle C. A., Laurencin C., Treadwell B. V., Biochem. Biophys. Res. Commun., 141, 904-911 (1986).
16. Alsalameh S., Amin R. J., Kunisch E., Jasin H. E., Kinne R. W., J. Rheumatol., 30, 1680-1690 (2003).
17. Dayer J. M., de Rochemonteix B., Burrus B., Demczuk S., Dinarello C. A., J. Clin. Invest., 77, 645-648 (1986).
18. Maimone D., Guazzi G. C., Annunziata P., J. Neurol. Sci., 146, 59-65 (1997).
19. Selmaj K., Raine C. S., Cannella B., Brosnan C. F., J. Clin. Invest., 87, 949-954 (1991).
20. Sharief M. K., Hentges R., N. Engl. J. Med., 325, 467-472 (1991).
21. Spuler S., Yousry T., Scheller A., Voltz R., Holler E., Hartmann M., Wick M., Hohlfeld R., J. Neuroimmunol., 66, 57-64 (1996).
22. Nagai H., Takaoka Y., Mori H., Mastuura N., Inflamm. Res., 45, 293-298 (1996).
23. Nagai H., Goto M., Kamada H., Boda K., Kitagaki K., Takaoka Y., Gen. Pharmacol., 30, 161-166 (1998).
24. Illei G. G., Lipsky P. E., Curr. Opin. Immunol., 12, 712-718 (2000).
25. Andreakos E., Expert. Opin. Biol. Ther., 3, 435-447 (2003).
26. Lorenz H. M., Expert. Opin. Investig. Drugs, 9, 1479-1490 (2000).
27. Gatto M. T., Tita B., Artico M., Saso L., Contraception, 65, 277-278 (2002).
28. Abouzid K. A., el-Abhar H. S., Arch. Pharm. Res., 26, 1-8 (2003).
29. Henke B. R., Aquino C. J., Birkemo L. S., Croom D. K., Dougherty R. W., Jr., Ervir G. N., Grizzle M. K., Hirst G. C., James M. K., Johnson M. F., Queen K. L., Sherrill R. G., Sugg E. E., Suh E. M., Szewczyk J. W., Unwalla R. J., Yingling J., Willson T. M., J. Med. Chem., 40, 2706-2725 (1997).
30. Cockerill S., Stubberfield C., Stables J., Carter M., Guntrip S., Smith K., McKeown S., Shaw R., Topley P., Thomsen L., Affleck K., Jowett A., Haye D., Willson M., Woollard P., Spalding D., Bioorg. Med. Chem. Lett., 11, 1401-1405 (2001).
31. Bruneau P., Delvare C., Edwards M. P., McMillan R. M., J. Med. Chem., 34, 1028-1036 (1991).