Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 11, 2001, Pages 1401-1405

  Cockerill, Stuart ^a   Stubberfield, Colin ^a   Stables, Jeremy ^a   Carter, Malcolm ^a   Guntrip, Stephen ^a   Smith, Kathryn ^a   McKeown, Steve ^a   Shaw, Robert ^a   Topley, Peter ^a   Thomsen, Lindy ^a   Affleck, Karen ^a   Jowett, Amanda ^a   Hayes, David ^a   Willson, Malcolm ^a   Woollard, Patrick ^a   Spalding, David ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GW 974; INDAZOLE DERIVATIVE; INDAZOLYLAMINOPYRIDOPYRIMIDINE DERIVATIVE; N(1 BENZYL 1H INDAZOL 5 YL) N,N DIMETHYLPYRIDO[3,4 D]PYRIMIDINE 4,6 DIAMINE; PROTEIN TYROSINE KINASE INHIBITOR; QUINAZOLINE DERIVATIVE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; RAT; TUMOR CELL LINE; TUMOR GROWTH; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; DISEASE MODELS, ANIMAL; MICE; MICE, SCID; PYRIMIDINES; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0035806197     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00219-0     Document Type: Article

References (16)