Stem cells: Implications for urology

Current Urology Reports

Volumn 6, Issue 1, 2005, Pages 49-54

  Lo, Kirk C ^b   Whirledge, Shannon ^b   Lamb, Dolores J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

Adult Stem Cell; Embryonic Stem Cell; Human Embryonic Stem Cell; Stem Cell; Stem Cell Research

Indexed keywords

EMBRYO RESEARCH; FORECASTING; HUMAN; MALE; MALE INFERTILITY; MEDICAL RESEARCH; RESEARCH ETHICS; REVIEW; RISK ASSESSMENT; STANDARD; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING; TREATMENT OUTCOME; UROLOGY;

BIOMEDICAL RESEARCH; EMBRYO RESEARCH; ETHICS, RESEARCH; FORECASTING; HUMANS; INFERTILITY, MALE; MALE; RISK ASSESSMENT; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING; TREATMENT OUTCOME; UROLOGY;

EID: 16644381686     PISSN: 15272737     EISSN: 15346285     Source Type: Journal    
DOI: 10.1007/s11934-005-0067-5     Document Type: Article

References (40)

1. Whetton AD, Graham GJ: Homing and mobilization in the stem cell niche. Trends Cell Biol 1999, 9:233–238. DOI: 10.1016/S0962-8924(99)01559-7
2. Ramalho-Santos M, Yoon S, Matsuzaki Y, et al.: “Stemness:” transcriptional profiling of embryonic and adult stem cells. Science 2002, 298:597–600. DOI: 10.1126/science.1072530
3. Ivanova NB, Dimos JT, Schaniel C, et al.: A stem cell molecular signature. Science 2002, 298:601–604. DOI: 10.1126/science.1073823
4. Evans MJ, Kaufman MH: Establishment in culture of pluripotential cells from mouse embryos. Nature 1981, 292:154–156. DOI: 10.1038/292154a0
5. Martin GR: Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 1981, 78:7634–7638. DOI: 10.1073/pnas.78.12.7634
6. Matsui Y, Zsebo K, Hogan BL: Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell 1992, 70:841–847. DOI: 10.1016/0092-8674(92)90317-6
7. Burdon T, Smith A, Savatier P: Signaling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol 2002, 12:432–438. DOI: 10.1016/S0962-8924(02)02352-8
8. Rohwedel J, Guan K, Hegert C, Wobus AM: Embryonic stem cells as an in vitro model for mutagenicity, cytotoxicity, and embryotoxicity studies: present state and future prospects. Toxicol In Vitro 2001, 15:741–753. DOI: 10.1016/S0887-2333(01)00074-1
9. Westphal CH, Leder P: Transposon-generated ‘knock-out’ and ‘knock-in’ gene-targeting constructs for use in mice. Curr Biol 1997, 7:530–533. DOI: 10.1016/S0960-9822(06)00224-7
10. Bjorklund LM, Sanchez-Pernaute R, Chung S, et al.: Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci U S A 2002, 99:2344–2349. DOI: 10.1073/pnas.022438099
11. Brustle O, Jones KN, Learish RD: Embryonic stem cell-derived glial precursors: a source of myelinating transplants. Science 1999, 285:754–756. DOI: 10.1126/science.285.5428.754
12. Lumelsky NF, Blondel OF, Laeng PF, et al.: Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001, 292:1389–1394. DOI: 10.1126/science.1058866
13. Wiles MV, Keller G: Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture. Development 1991, 111:259–267.
14. Risau W, Sariola H, Zerwes HG, et al.: Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development 1988, 102:471–478.
15. Rohwedel J, Maltsev V, Bober E, et al.: Muscle cell differentiation of embryonic stem cells reflects myogenesis in vivo: developmentally regulated expression of myogenic determination genes and functional expression of ionic currents. Dev Biol 1994, 164:87–101. DOI: 10.1006/dbio.1994.1182
16. Kramer J, Hegert C, Guan K, et al.: Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2 and BMP-4. Mech Dev 2000, 92:193–205. DOI: 10.1016/S0925-4773(99)00339-1
17. Hamazaki T, Iiboshi Y, Oka M, et al.: Hepatic maturation in differentiating embryonic stem cells in vitro. FEBS Lett 2001, 497:15–19. DOI: 10.1016/S0014-5793(01)02423-1
18. Dani C, Smith AG, Dessolin S, et al.: Differentiation of embryonic stem cells into adipocytes in vitro. J Cell Sci 1997, 110:1279–1285.
19. Hubner K, Fuhrmann G, Christenson LK, et al.: Derivation of oocytes from mouse embryonic stem cells. Science 2003, 300:1251–1256. DOI: 10.1126/science.1083452
20. Toyooka Y, Tsunekawa N, Akasu R, Noce T: Embryonic stem cells can form germ cells in vitro. Proc Natl Acad Sci U S A 2003, 100:11457–11462. st of two reports of male germ cell derivation from embryonic stem cells. These represent a major breakthrough in gem cell research in vitro DOI: 10.1073/pnas.1932826100
21. Geijsen N, Horoschak M, Kim K, et al.: Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature 2004, 427:148–154. First of two reports of male germ cell derivation from embryonic stem cells. These represent a major breakthrough in gem cell research in vitro. DOI: 10.1038/nature02247
22. Ruiz-Canela M: Embryonic stem cell research: the relevance of ethics in the progress of science. Med Sci Monit 2002, 8:SR21-SR26.
23. McLaren A: Ethical and social considerations of stem cell research. Nature 2001, 414:129–131. DOI: 10.1038/35102194
24. Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al.: Embryonic stem cell lines derived from human blastocysts. Science 1998, 282:1145–1147. DOI: 10.1126/science.282.5391.1145
25. Campbell KH, McWhir J, Ritchie WA, Wilmut I: Sheep cloned by nuclear transfer from a cultured cell line. Nature 1996, 380:64–66. DOI: 10.1038/380064a0
26. Till JE, McCulloch EA: A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res 1961, 14:213–222. DOI: 10.2307/3570892
27. Gage FH: Mammalian neural stem cells. Science 2000, 287:1433–1438. DOI: 10.1126/science.287.5457.1433
28. Vessey CJ, dela Hall PM: Hepatic stem cells: a review. Pathology 2001, 33:130–141. DOI: 10.1080/00313020120038719
29. Goldring K, Partridge T, Watt D: Muscle stem cells. J Pathol 2002, 197:457–467. DOI: 10.1002/path.1157
30. Feldman JL, Stockdale FE: Temporal appearance of satellite cells during myogenesis. Dev Biol 1992, 153:217–226. DOI: 10.1016/0012-1606(92)90107-R
31. Rando TA, Blau HM: Methods for myoblast transplantation. Methods Cell Biol 1997, 52:261–272. DOI: 10.1016/S0091-679X(08)60382-9
32. Brinster RL, Avarbock MR: Germline transmission of donor haplotype following spermatogonial transplantation. Proc Natl Acad Sci U S A 1994, 91:11303–11307. DOI: 10.1073/pnas.91.24.11303
33. Brinster RL, Zimmermann JW: Spermatogenesis following male germ-cell transplantation. Proc Natl Acad Sci U S A 1994, 91:11298–11302. DOI: 10.1073/pnas.91.24.11298
34. Clouthier DE, Avarbock MR, Maika SD, et al.: Rat spermatogenesis in mouse testis. Nature 1996, 381:418–421. DOI: 10.1038/381418a0
35. Cozzolino DJ, Lamb DJ: Germ cell transplantation: a potential treatment of severe testicular failure. Curr Urol Rep 2000, 1:262–265. DOI: 10.1007/s11934-000-0005-5
36. Lo KC, Lei Z, Rao CH, et al.: De novo testosterone production in luteinizing hormone receptor knockout mice after transplantation of Leydig stem cells. Endocrinology 2004, 145:4011–4015. This is the first report of the isolation of potential Leydig stem cells from mice. Transplantation of the Leydig stem cells leads to the production of testosterone and restoration of spermatogenesis in previously infertile recipients. DOI: 10.1210/en.2003-1729
37. Cicognani A, Pasini A, Pession A, et al.: Gonadal function and pubertal development after treatment of a childhood malignancy. J Pediatr Endocrinol Metab 2003, 16(suppl 2):321–326.
38. Atala A: Tissue engineering, stem cells, and cloning for the regeneration of urologic organs. Clin Plast Surg 2003, 30:649–667. DOI: 10.1016/S0094-1298(03)00094-4
39. Koh CJ, Atala A: Tissue engineering, stem cells, and cloning: opportunities for regenerative medicine. J Am Soc Nephrol 2004, 15:1113–1125. DOI: 10.1097/01.ASN.0000119683.59068.F0
40. Machluf M, Orsola A, Boorjian S, et al.: Microencapsulation of Leydig cells: a system for testosterone supplementation. Endocrinology 2003, 144:4975–4979. Tissue engineering using biomaterials to deliver biologic elements has come a long way. A microencapsulation system described in this article represents a potential treatment for hypogonadal individuals by supplementing testosterone. DOI: 10.1210/en.2003-0411