Towards a fully synthetic substitute of alginate: Optimization of a thermal gelation/chemical cross-linking scheme ("tandem" gelation) for the production of beads and liquid-core capsules

Biotechnology and Bioengineering

Volumn 88, Issue 6, 2004, Pages 740-749

  Cellesi, F ^a,b   Weber, W ^c   Fussenegger, M ^c   Hubbell, J A ^a   Tirelli, N ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c ETH ZURICH   (Switzerland)

Author keywords

Cell encapsulation; Michael type addition; Set break up; Thermal gelation

Indexed keywords

CROSSLINKING; GELATION; HYDROGELS; MOLECULAR STRUCTURE; PH EFFECTS; THERMAL EFFECTS;

ALGINATE; BIOACTIVITY; MICROCAPSULES; SYNTHETIC POLYMERS;

POLYSACCHARIDES;

ALGINIC ACID; CALCIUM ALGINATE; BIOMATERIAL; CROSS LINKING REAGENT; GLUCURONIC ACID; HEXURONIC ACID; MICROSPHERE;

ARTICLE; BINDING KINETICS; CHEMICAL BINDING; CHO CELL; CROSS LINKING; ELASTICITY; ENCAPSULATION; GELATION; INCUBATION TIME; MICROCAPSULE; MOLECULAR BIOLOGY; NONHUMAN; PH MEASUREMENT; POLYMERIZATION; PROCESS MONITORING; PURIFICATION; REACTION OPTIMIZATION; SYNTHESIS; TEMPERATURE MEASUREMENT; TRANSPORT KINETICS; ANIMAL; CHEMISTRY; CRICETULUS; CULTURE TECHNIQUE; HAMSTER; HYDROGEL; IMMOBILIZED CELL; MATERIALS TESTING; METHODOLOGY; PHASE TRANSITION; PHYSIOLOGY; TEMPERATURE;

ALGINATES; ANIMALS; BIOCOMPATIBLE MATERIALS; CAPSULES; CELL CULTURE TECHNIQUES; CELLS, IMMOBILIZED; CHO CELLS; CRICETINAE; CRICETULUS; CROSS-LINKING REAGENTS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGELS; MATERIALS TESTING; MICROSPHERES; PHASE TRANSITION; TEMPERATURE;

EID: 16644373125     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20264     Document Type: Article

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