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Volumn 28, Issue 1, 2004, Pages 51-63

The Efficacy of Acamprosate in the Maintenance of Abstinence in Alcohol-Dependent Individuals: Results of a Meta-Analysis

Author keywords

Alcohol Dependency; Alcohol Drinking; Meta Analysis; Randomized Controlled Trials; Treatment Outcome

Indexed keywords

ACAMPROSATE; PLACEBO;

EID: 1642576316     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000108656.81563.05     Document Type: Review
Times cited : (303)

References (68)
  • 1
    • 0031813519 scopus 로고    scopus 로고
    • Mechanisms of action of acamprosate. Part II. Ethanol dependence modifies effects of acamprosate on NMDA receptor binding in membranes from rat cerebral cortex
    • Al Quatari M, Bouchenafa O, Littleton J (1998) Mechanisms of action of acamprosate. Part II. Ethanol dependence modifies effects of acamprosate on NMDA receptor binding in membranes from rat cerebral cortex. Alcohol Clin Exp Res 22:810-814.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 810-814
    • Al Quatari, M.1    Bouchenafa, O.2    Littleton, J.3
  • 4
    • 0033759089 scopus 로고    scopus 로고
    • An open study with acamprosate in Belgium and Luxemburg: Results on sociodemographics, supportive treatment and outcome
    • Ansoms C, Deckers F, Lehert P, Pelc I, Potgeiter A (2000) An open study with acamprosate in Belgium and Luxemburg: results on sociodemographics, supportive treatment and outcome. Eur Addict Res 6:132-140.
    • (2000) Eur Addict Res , vol.6 , pp. 132-140
    • Ansoms, C.1    Deckers, F.2    Lehert, P.3    Pelc, I.4    Potgeiter, A.5
  • 5
    • 0034813626 scopus 로고    scopus 로고
    • Pharmacological approaches to the management of alcoholism
    • Anton RF (2001) Pharmacological approaches to the management of alcoholism. J Clin Psychiatry (Suppl 20) 62:11-17.
    • (2001) J Clin Psychiatry (Suppl 20) , vol.62 , pp. 11-17
    • Anton, R.F.1
  • 6
    • 0038249078 scopus 로고    scopus 로고
    • Current pharmacotherapies of alcoholism: A U.S. perspective
    • Anton RF, Swift RM (2003) Current pharmacotherapies of alcoholism: a U.S. perspective. Am J Addict (Suppl 1) 12:S53-S68.
    • (2003) Am J Addict (Suppl 1) , vol.12
    • Anton, R.F.1    Swift, R.M.2
  • 10
    • 0031800435 scopus 로고    scopus 로고
    • Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: A controlled study
    • Besson J, Aeby F, Kasas A, Lehert P, Potgieter A (1998) Combined efficacy of acamprosate and disulfiram in the treatment of alcoholism: a controlled study. Alcohol Clin Exp Res 22:573-579.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 573-579
    • Besson, J.1    Aeby, F.2    Kasas, A.3    Lehert, P.4    Potgieter, A.5
  • 11
    • 0035970794 scopus 로고    scopus 로고
    • A comparison of statistical methods for meta-analysis
    • Brockwell SE, Gordon IR (2001) A comparison of statistical methods for meta-analysis. Stat Med 20:825-840.
    • (2001) Stat Med , vol.20 , pp. 825-840
    • Brockwell, S.E.1    Gordon, I.R.2
  • 12
    • 0026777695 scopus 로고
    • Lifetime and 6-month prevalence of abuse and dependence of alcohol in the Munich follow-up study
    • Bronisch T, Wittchen HU (1992) Lifetime and 6-month prevalence of abuse and dependence of alcohol in the Munich follow-up study. Eur Arch Psychiatry Clin Neurosci 241:273-282.
    • (1992) Eur Arch Psychiatry Clin Neurosci , vol.241 , pp. 273-282
    • Bronisch, T.1    Wittchen, H.U.2
  • 15
    • 0034116102 scopus 로고    scopus 로고
    • United Kingdom Multicentre Acamprosate Study (UKMAS): A 6-month prospective study of acamprosate versus placebo in preventing relapse after withdrawal from alcohol
    • Chick J, Howlett H, Morgan MY, Ritson B (2000) United Kingdom Multicentre Acamprosate Study (UKMAS): a 6-month prospective study of acamprosate versus placebo in preventing relapse after withdrawal from alcohol. Alcohol Alcohol 35:176-187.
    • (2000) Alcohol Alcohol , vol.35 , pp. 176-187
    • Chick, J.1    Howlett, H.2    Morgan, M.Y.3    Ritson, B.4
  • 17
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test, BMJ 315:629-634.
    • (1997) BMJ , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 18
    • 0036796173 scopus 로고    scopus 로고
    • Cognitive behavioural therapy combined with the relapse-prevention medication acamprosate: Are short-term outcomes for alcohol dependence improved?
    • Feeney GF, Young RM, Connor JP, Tucker J, McPherson A (2002) Cognitive behavioural therapy combined with the relapse-prevention medication acamprosate: are short-term outcomes for alcohol dependence improved? Aust NZ J Psychiatry 36:622-628.
    • (2002) Aust NZ J Psychiatry , vol.36 , pp. 622-628
    • Feeney, G.F.1    Young, R.M.2    Connor, J.P.3    Tucker, J.4    McPherson, A.5
  • 19
    • 0037165738 scopus 로고    scopus 로고
    • Acamprosate and psychosocial support an integrated approach to the prevention of relapse in alcohol-dependent patients in Switzerland
    • Fuchs W-J, Riebenfeld D (2002) Acamprosate and psychosocial support an integrated approach to the prevention of relapse in alcohol-dependent patients in Switzerland. Schweiz Rundsch Med Prax 91:735-742.
    • (2002) Schweiz Rundsch Med Prax , vol.91 , pp. 735-742
    • Fuchs, W.-J.1    Riebenfeld, D.2
  • 20
    • 0033553203 scopus 로고    scopus 로고
    • Pharmacological treatment of alcohol dependence: A review of the evidence
    • Garbutt JC, West SL, Carey TS, Lohr KN, Crews FT (1999) Pharmacological treatment of alcohol dependence: a review of the evidence JAMA 281:1318-1325.
    • (1999) JAMA , vol.281 , pp. 1318-1325
    • Garbutt, J.C.1    West, S.L.2    Carey, T.S.3    Lohr, K.N.4    Crews, F.T.5
  • 21
    • 0030739021 scopus 로고    scopus 로고
    • Acamprosate and prevention of relapse in alcoholics. Results of a randomized, placebo-controlled, double-blind study in out-patient alcoholics in The Netherlands, Belgium and Luxembourg
    • Geerlings PJ, Ansoms C, van den Brink W (1997) Acamprosate and prevention of relapse in alcoholics. Results of a randomized, placebo-controlled, double-blind study in out-patient alcoholics in The Netherlands, Belgium and Luxembourg. Eur Addict Res 3:129-137.
    • (1997) Eur Addict Res , vol.3 , pp. 129-137
    • Geerlings, P.J.1    Ansoms, C.2    Van Den Brink, W.3
  • 22
    • 0026744014 scopus 로고
    • Effects of fluoxetine and Ca-acetyl-homotaurinate on alcohol intake in familial and non-familial alcoholic patients
    • Gerra G, Caccavari R, Delsignore R, Bocchi R, Fertonani G, Passeri M. (1992) Effects of fluoxetine and Ca-acetyl-homotaurinate on alcohol intake in familial and non-familial alcoholic patients. Curr Ther Res Clin Exp 52:291-295.
    • (1992) Curr Ther Res Clin Exp , vol.52 , pp. 291-295
    • Gerra, G.1    Caccavari, R.2    Delsignore, R.3    Bocchi, R.4    Fertonani, G.5    Passeri, M.6
  • 23
    • 0030763094 scopus 로고    scopus 로고
    • Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States
    • Grant BF (1997) Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States. J Stud Alcohol 58:464-473.
    • (1997) J Stud Alcohol , vol.58 , pp. 464-473
    • Grant, B.F.1
  • 24
    • 0034855498 scopus 로고    scopus 로고
    • Acamprosate during and after acute alcohol withdrawal: A double-blind placebo-controlled study in Spain
    • Gual A, Lehert P (2001) Acamprosate during and after acute alcohol withdrawal: a double-blind placebo-controlled study in Spain. Alcohol Alcohol 36:413-418.
    • (2001) Alcohol Alcohol , vol.36 , pp. 413-418
    • Gual, A.1    Lehert, P.2
  • 27
    • 0024601904 scopus 로고
    • Multicenter trial of calcium bis (acetylhomotaurinate) in treatment of alcohol dependence
    • Hillemond B, Lhuintre JP, Steru L, Boismare F, Daoust M, Moore N, et al. (1989) Multicenter trial of calcium bis (acetylhomotaurinate) in treatment of alcohol dependence. Rev Alcohol 34:9-28.
    • (1989) Rev Alcohol , vol.34 , pp. 9-28
    • Hillemond, B.1    Lhuintre, J.P.2    Steru, L.3    Boismare, F.4    Daoust, M.5    Moore, N.6
  • 30
    • 0000612139 scopus 로고
    • A non parametric technique for meta-analysis effect size calculation
    • Kraemer HC, Andrews G (1982) A non parametric technique for meta-analysis effect size calculation. Psychol Bull 91:404-412.
    • (1982) Psychol Bull , vol.91 , pp. 404-412
    • Kraemer, H.C.1    Andrews, G.2
  • 31
    • 0034821702 scopus 로고    scopus 로고
    • Efficacy of naltrexone and acamprosate for alcoholism treatment: A meta-analysis
    • Kranzler HR, Van Kirk J (2001) Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis. Alcohol Clin Exp Res 25: 1335-1341.
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 1335-1341
    • Kranzler, H.R.1    Van Kirk, J.2
  • 32
    • 0027295001 scopus 로고
    • Acamprosate-a stabilizing factor in long-term withdrawal of alcoholic patients
    • Ladewig D, Knecht T, Leher P, Fendl A (1993) Acamprosate-a stabilizing factor in long-term withdrawal of alcoholic patients. Ther Umscl 50:182-188.
    • (1993) Ther Umscl , vol.50 , pp. 182-188
    • Ladewig, D.1    Knecht, T.2    Leher, P.3    Fendl, A.4
  • 33
    • 0027902912 scopus 로고
    • Review and discussion of statistical analysis of controlled clinical trials in alcoholism
    • Lehert P (1993) Review and discussion of statistical analysis of controlled clinical trials in alcoholism. Alcohol Alcohol Suppl 2:157-163.
    • (1993) Alcohol Alcohol Suppl , vol.2 , pp. 157-163
    • Lehert, P.1
  • 36
    • 0038587675 scopus 로고    scopus 로고
    • Pharmacological mechanisms of naltrexone and acamprosate in the prevention of relapse in alcohol dependence
    • Littleton J, Zieglgänsberger W (2003) Pharmacological mechanisms of naltrexone and acamprosate in the prevention of relapse in alcohol dependence. Am J Addict (Suppl 1) 12:S3-S11.
    • (2003) Am J Addict (Suppl 1) , vol.12
    • Littleton, J.1    Zieglgänsberger, W.2
  • 37
    • 10344261183 scopus 로고    scopus 로고
    • Results of the multicenter study of acamprosate in the treatment of alcoholism
    • Mason BJ (2001) Results of the multicenter study of acamprosate in the treatment of alcoholism (abstract). Biol Psychiatry (Suppl 8) 48:77S
    • (2001) Biol Psychiatry (Suppl 8) , vol.48
    • Mason, B.J.1
  • 39
    • 0030015103 scopus 로고    scopus 로고
    • Explaining abstinence rates following treatment for alcohol abuse: A quantitative synthesis of patient, research design and treatment effects
    • Monahan S, Finney JW (1996) Explaining abstinence rates following treatment for alcohol abuse: a quantitative synthesis of patient, research design and treatment effects. Addiction 91:787-805.
    • (1996) Addiction , vol.91 , pp. 787-805
    • Monahan, S.1    Finney, J.W.2
  • 40
    • 0031804862 scopus 로고    scopus 로고
    • The quality of alcohol treatment research: An examination of influential controlled trials and development of a quality rating system
    • Moncrieff J, Drummond DC (1998) The quality of alcohol treatment research: an examination of influential controlled trials and development of a quality rating system. Addiction 93:811-823.
    • (1998) Addiction , vol.93 , pp. 811-823
    • Moncrieff, J.1    Drummond, D.C.2
  • 41
    • 0036201152 scopus 로고    scopus 로고
    • Methodological characteristics and quality of alcohol treatment outcome studies, 1970-98: An expanded evaluation
    • Moyer A, Finney JW, Swearingen CE (2002) Methodological characteristics and quality of alcohol treatment outcome studies, 1970-98: an expanded evaluation. Addiction 97:253-263.
    • (2002) Addiction , vol.97 , pp. 253-263
    • Moyer, A.1    Finney, J.W.2    Swearingen, C.E.3
  • 42
    • 0031868767 scopus 로고    scopus 로고
    • Mechanisms of action of acamprosate. Part I. Characterization of spermidine-sensitive acamprosate binding site in rat brain
    • Naassila M, Hammoumi S, Legrand E, Durbin P, Daoust M (1998) Mechanisms of action of acamprosate. Part I. Characterization of spermidine-sensitive acamprosate binding site in rat brain. Alcohol Clin Exp Res 22:802-809.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 802-809
    • Naassila, M.1    Hammoumi, S.2    Legrand, E.3    Durbin, P.4    Daoust, M.5
  • 43
    • 0037347389 scopus 로고    scopus 로고
    • Acamprosate in Korean alcohol-dependent patients: A multi-centre, randomized, double-blind, placebo-controlled study
    • Namkoong K, Lee B-O, Lee P-G, Choi M-J, Lee E (2003) Acamprosate in Korean alcohol-dependent patients: a multi-centre, randomized, double-blind, placebo-controlled study. Alcohol Alcohol 38:135-141.
    • (2003) Alcohol Alcohol , vol.38 , pp. 135-141
    • Namkoong, K.1    Lee, B.-O.2    Lee, P.-G.3    Choi, M.-J.4    Lee, E.5
  • 44
    • 0029057803 scopus 로고
    • Double-blind randomized multicentre trial of acamprosate in maintaining abstinence from alcohol
    • Paille FM, Guelfi JD, Perkins AC, Royer RJ, Steru L, Parot P (1995) Double-blind randomized multicentre trial of acamprosate in maintaining abstinence from alcohol. Alcohol Alcohol 30:239-247.
    • (1995) Alcohol Alcohol , vol.30 , pp. 239-247
    • Paille, F.M.1    Guelfi, J.D.2    Perkins, A.C.3    Royer, R.J.4    Steru, L.5    Parot, P.6
  • 45
    • 0036799477 scopus 로고    scopus 로고
    • The European NEAT program: An integrated approach using acamprosate and psychosocial support for the prevention of relapse in alcohol-dependent patients with a statistical modeling of therapy success prediction
    • Pelc I, Ansoms C, Lehert P, Fischer F, Fuchs W, Landron F, Preto AJP, Morgan MY (2002) The European NEAT program: an integrated approach using acamprosate and psychosocial support for the prevention of relapse in alcohol-dependent patients with a statistical modeling of therapy success prediction. Alcohol Clin Exp Res 26:1529-1538.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 1529-1538
    • Pelc, I.1    Ansoms, C.2    Lehert, P.3    Fischer, F.4    Fuchs, W.5    Landron, F.6    Preto, A.J.P.7    Morgan, M.Y.8
  • 46
    • 0002881197 scopus 로고
    • Calcium acetyl homotaurinate for maintaining abstinence in weaned alcoholic patients: A placebo-controlled double-blind multi-centre study
    • (Naranjo C, Sellers E eds). Springer Verlag, New York
    • Pelc I, Le Bon O, Verbanck P, Lehert PH, Opsomer L (1992) Calcium acetyl homotaurinate for maintaining abstinence in weaned alcoholic patients: a placebo-controlled double-blind multi-centre study, in Novel Pharmacological Interventions for Alcoholism (Naranjo C, Sellers E eds), pp 348-352. Springer Verlag, New York.
    • (1992) Novel Pharmacological Interventions for Alcoholism , pp. 348-352
    • Pelc, I.1    Le Bon, O.2    Verbanck, P.3    Lehert, P.H.4    Opsomer, L.5
  • 47
    • 0031182913 scopus 로고    scopus 로고
    • Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients. A 90-day placebo-controlled dose-finding study
    • Pelc I, Verbanck P, Le Bon O, Gavrilovic M, Lion K, Lehert P (1997) Efficacy and safety of acamprosate in the treatment of detoxified alcohol-dependent patients. A 90-day placebo-controlled dose-finding study. Br J Psychiatry 171:73-77.
    • (1997) Br J Psychiatry , vol.171 , pp. 73-77
    • Pelc, I.1    Verbanck, P.2    Le Bon, O.3    Gavrilovic, M.4    Lion, K.5    Lehert, P.6
  • 48
    • 0034699983 scopus 로고    scopus 로고
    • Use of lipid lowering drugs for primary prevention of coronary heart disease: Meta-analysis of randomized trials
    • Pignone M, Phillips C, Mulrow C (2000) Use of lipid lowering drugs for primary prevention of coronary heart disease: meta-analysis of randomized trials. BMJ 321:983-986.
    • (2000) BMJ , vol.321 , pp. 983-986
    • Pignone, M.1    Phillips, C.2    Mulrow, C.3
  • 49
    • 0030664374 scopus 로고    scopus 로고
    • Acamprosate treatment in a long-term community-based alcohol rehabilitation programme
    • Poldrugo F (1997) Acamprosate treatment in a long-term community-based alcohol rehabilitation programme. Addiction 92:1537-1546.
    • (1997) Addiction , vol.92 , pp. 1537-1546
    • Poldrugo, F.1
  • 50
    • 0034646855 scopus 로고    scopus 로고
    • Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons
    • Popp RL, Lovinger DM (2000) Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons. Eur J Neurosci 394:221-231.
    • (2000) Eur J Neurosci , vol.394 , pp. 221-231
    • Popp, R.L.1    Lovinger, D.M.2
  • 51
    • 0035001893 scopus 로고    scopus 로고
    • The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801
    • Rammes G, Mahal B, Putzke J, Parsons C, Spielmanns P, Pestel E, Spanagel R, Zieglgänsberger W, Schadrack J (2001) The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801. Neuropharmacology 40:749-760.
    • (2001) Neuropharmacology , vol.40 , pp. 749-760
    • Rammes, G.1    Mahal, B.2    Putzke, J.3    Parsons, C.4    Spielmanns, P.5    Pestel, E.6    Spanagel, R.7    Zieglgänsberger, W.8    Schadrack, J.9
  • 52
    • 0035143093 scopus 로고    scopus 로고
    • Two methods of estimating health cost linked to alcoholism in France (with a note on social cost)
    • Reynaud M, Gaudin-Colombel AF, Le Pen C (2001) Two methods of estimating health cost linked to alcoholism in France (with a note on social cost). Alcohol Alcohol 36:89-95.
    • (2001) Alcohol Alcohol , vol.36 , pp. 89-95
    • Reynaud, M.1    Gaudin-Colombel, A.F.2    Le Pen, C.3
  • 53
    • 0002586190 scopus 로고
    • The economic cost of alcohol abuse and alcohol dependence: 1990
    • Rice DP (1993) The economic cost of alcohol abuse and alcohol dependence: 1990. Alcohol Health Res World 17:10-11.
    • (1993) Alcohol Health Res World , vol.17 , pp. 10-11
    • Rice, D.P.1
  • 54
    • 0030013090 scopus 로고    scopus 로고
    • Does acamprosate influence alcohol consumption of weaned alcoholics?
    • Roussaux JP, Hers D, Ferauge M (1996) Does acamprosate influence alcohol consumption of weaned alcoholics? J Pharm Belg 51:65-68.
    • (1996) J Pharm Belg , vol.51 , pp. 65-68
    • Roussaux, J.P.1    Hers, D.2    Ferauge, M.3
  • 55
    • 0034842012 scopus 로고    scopus 로고
    • Naltrexone versus acamprosate: One year follow-up of alcohol dependence of alcohol dependence treatment
    • Rubio G, Jimenez-Arriero MA, Ponce G, Palomo T (2001) Naltrexone versus acamprosate: one year follow-up of alcohol dependence of alcohol dependence treatment. Alcohol Alcohol 36:419-425.
    • (2001) Alcohol Alcohol , vol.36 , pp. 419-425
    • Rubio, G.1    Jimenez-Arriero, M.A.2    Ponce, G.3    Palomo, T.4
  • 56
    • 0034763373 scopus 로고    scopus 로고
    • Aspirin for primary prevention of coronary heart disease: Safety and absolute benefit related to coronary risk derived from meta-analysis of randomized trials
    • Sanmuganathan PS, Ghahramani P, Jackson PR, Wallis EJ, Ramsey LE (2001) Aspirin for primary prevention of coronary heart disease: safety and absolute benefit related to coronary risk derived from meta-analysis of randomized trials. Heart 85:265-271.
    • (2001) Heart , vol.85 , pp. 265-271
    • Sanmuganathan, P.S.1    Ghahramani, P.2    Jackson, P.R.3    Wallis, E.J.4    Ramsey, L.E.5
  • 57
    • 0029737567 scopus 로고    scopus 로고
    • Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence
    • Sass H, Soyka M, Mann K, Zieglgänsberger W (1996) Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry 53:673-680.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 673-680
    • Sass, H.1    Soyka, M.2    Mann, K.3    Zieglgänsberger, W.4
  • 58
    • 0001034535 scopus 로고    scopus 로고
    • Meta-analysis of pharmotherapeutic trials
    • (Zernig G, Saria A, Kurz M, O'Malley S eds). Innsbruck University Press, Innsbruck, Austria
    • Schoechlin C, Engel RR (2000) Meta-analysis of pharmotherapeutic trials, in Handbook of Alcoholism (Zernig G, Saria A, Kurz M, O'Malley S eds), pp 339-351. Innsbruck University Press, Innsbruck, Austria.
    • (2000) Handbook of Alcoholism , pp. 339-351
    • Schoechlin, C.1    Engel, R.R.2
  • 60
    • 1642571527 scopus 로고    scopus 로고
    • Advances in the treatment of alcohol dependence; Pharmacological relapse prevention
    • Smolka MN, Kiefer F, Mann K (2003) Advances in the treatment of alcohol dependence; Pharmacological relapse prevention (in German). MMW-Fortsch Medizin 145:65-69.
    • (2003) MMW-Fortsch Medizin , vol.145 , pp. 65-69
    • Smolka, M.N.1    Kiefer, F.2    Mann, K.3
  • 61
    • 0038587645 scopus 로고    scopus 로고
    • Use of acamprosate and opioid antagonists in the treatment of alcohol dependence: A European perspective
    • Soyka M, Chick J (2003) Use of acamprosate and opioid antagonists in the treatment of alcohol dependence: a European perspective. Am J Addict (Suppl 1) 12:S69-S80.
    • (2003) Am J Addict (Suppl 1) , vol.12
    • Soyka, M.1    Chick, J.2
  • 62
    • 0036364469 scopus 로고    scopus 로고
    • Use of acamprosate and different kinds of psychosocial support in relapse prevention of alcoholism. Results of a non-blind, multicentre study
    • Soyka M, Preuss U, Schuetz C (2002) Use of acamprosate and different kinds of psychosocial support in relapse prevention of alcoholism. Results of a non-blind, multicentre study. Drugs R D 3:1-12.
    • (2002) Drugs R D , vol.3 , pp. 1-12
    • Soyka, M.1    Preuss, U.2    Schuetz, C.3
  • 63
    • 0028677850 scopus 로고
    • Acamprosate: A new pharmacotherapeutic approach to relapse prevention in alcoholism-preliminary data
    • Soyka M, Sass H (1994) Acamprosate: a new pharmacotherapeutic approach to relapse prevention in alcoholism-preliminary data. Alcohol Alcohol Suppl 2:531-536.
    • (1994) Alcohol Alcohol Suppl , vol.2 , pp. 531-536
    • Soyka, M.1    Sass, H.2
  • 64
    • 0003276205 scopus 로고    scopus 로고
    • Drug therapy for alcohol dependence
    • Swift RM (1999) Drug therapy for alcohol dependence. N Engl J Med 340:1482-1487.
    • (1999) N Engl J Med , vol.340 , pp. 1482-1487
    • Swift, R.M.1
  • 65
    • 0034018047 scopus 로고    scopus 로고
    • Acamprosate and relapse prevention in the treatment of alcohol dependence: A placebo-controlled study
    • Tempesta E, Janiri L, Bignamini A, Chabac S, Potgieter A (2000) Acamprosate and relapse prevention in the treatment of alcohol dependence: a placebo-controlled study. Alcohol Alcohol 35:202-209.
    • (2000) Alcohol Alcohol , vol.35 , pp. 202-209
    • Tempesta, E.1    Janiri, L.2    Bignamini, A.3    Chabac, S.4    Potgieter, A.5


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