Microencapsulation of hydrophilic drug substances using biodegradable polyesters. Part II: Implants allowing controlled drug release - A feasibility study using bisphosphonates

Journal of Microencapsulation

Volumn 21, Issue 2, 2004, Pages 137-149

  Weidenauer, U ^a   Bodmer, D ^b   Kissel, T ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Biodegradable polymers; Bisphosphonates; Hydrophilic drug salts; Implants; Melt extrusion; Microparticles; Spray drying technique

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CHITOSAN; DRUG CARRIER; PAMIDRONIC ACID; POLYESTER; POLYGLACTIN; POLYMER; SODIUM CHLORIDE; WATER;

ARTICLE; BIODEGRADABILITY; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; EMBEDDING; FEASIBILITY STUDY; HYDROPHILICITY; HYDROPHOBICITY; IMPLANT; IN VITRO STUDY; LABORATORY TEST; MICROENCAPSULATION; PARTICLE SIZE; POLYMERIZATION; SPRAY DRYING;

ADJUVANTS, PHARMACEUTIC; ANTI-INFLAMMATORY AGENTS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; CHITIN; CHITOSAN; DIPHOSPHONATES; DRUG COMPOUNDING; DRUG IMPLANTS; FEASIBILITY STUDIES; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; POLYESTERS; POLYGLYCOLIC ACID; SUCROSE; SURFACE PROPERTIES;

EID: 1642569183     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652040310001637857     Document Type: Article

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