Synthesis of a series of cytotoxic 2-acyl-1,2-dihydroellipticines which inhibit topoisomerase II

Anti-Cancer Drug Design

Volumn 11, Issue 4, 1996, Pages 311-324

  Devraj, Rajesh ^a   Jurayj, Jurjus ^a   Fernandez, Jeffrey A ^b   Barrett, John F ^b   Cushman, Mark ^a  

^a PURDUE UNIVERSITY   (United States)

^b R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

2 acyl 1,2 dihydroellipticine; Antitumor; Cytotoxicity; Topoisomerase II

Indexed keywords

CHLORIDE; DNA TOPOISOMERASE (ATP HYDROLYSING); ELLIPTICINE DERIVATIVE; TETRAHYDROFURAN;

ACYLATION; ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REDUCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELLS, CULTURED; DNA TOPOISOMERASES, TYPE II; DRUG SCREENING ASSAYS, ANTITUMOR; ELLIPTICINES; ENZYME INHIBITORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; TUMOR CELLS, CULTURED;

EID: 0030014417     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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