Reciprocal Regulation of Thymus and Activation-Regulated Chemokine/Macrophage-Derived Chemokine Production by Interleukin (IL)-4/IL-13 and Interferon-γ in HaCaT Keratinocytes Is Mediated by Alternations in E-cadherin Distribution

Journal of Investigative Dermatology

Volumn 122, Issue 1, 2004, Pages 20-28

  Fujii Maeda, Shoko ^a,b   Kajiwara, Keiich ^a   Ikizawa, Kouichi ^a   Shinazawa, Miki ^a   Yu, Bin ^b   Koga, Tetsuya ^b   Furue, Masutaka ^b   Yanagihara, Yukiyoshi ^a  

^a SAGAMIHARA NATIONAL HOSPITAL   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

E cadherin; IFN g; IL 4; Keratinocyte; TARC

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CELL ADHESION MOLECULE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 4; MACROPHAGE DERIVED CHEMOKINE; PLAKOGLOBIN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UVOMORULIN;

ARTICLE; CELL JUNCTION; CELL LINE; CHELATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; HUMAN; HUMAN CELL; KERATINOCYTE; NEWBORN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; THYMUS; UPREGULATION;

EID: 1642493843     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202X.2003.22103.x     Document Type: Article

References (36)

1. Akaiwa M, Yu B, Umeshita-Suyama R, et al: Localization of human interleukin 13 receptor in non-haematopoietic cells. Cytokine 13:75-84, 2001
2. Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G: A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J Leukoc Biol 70:617-623, 2001
3. Alferink J, Lieberam I, Reindl W, et al: Compartmentalized production of CCL17 in vivo: Strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen. J Exp Med 197:585-599, 2003
4. Andrew DP, Chang M, McNinch J, et al: STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13. J Immunol 161:5027-5038, 1998
5. Bonecchi R, Sozzani S, Stine JT, et al: Divergent effects of interleukin-4 and interferon-γ on macrophage-derived chemokine production: An amplification circuit of polarized T helper 2 responses. Blood 92:2668-2671, 1998
6. Boukamp P, Petrussevska RT, Breitkreuts D, Hornung J, Markham A, Fusenig NE: Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 106:761-771, 1988
7. David M, Ford D, Bertoglio J, Maizel AL, Pierre J: Induction of the IL-13 receptor α2-chain by IL-4 and IL-13 in human keratinocytes: Involvement of STAT6, ERK and p38 MAPK pathways. Oncogene 20:6660-6668, 2001
8. Fenyves AM, Behrens J, Spanel-Borowski K: Cultured microvascular endothelial cells (MVEC) differ in cytoskeleton, expression of cadherins and fibronectin matrix: A study under the influence of interferon-γ. J Cell Sci 106:879-890, 1993
9. Fukuda K, Fujitsu Y, Seki K, Kumagai N, Nishida T: Differential expression of thymus- and activation-regulated chemokine (CCL17) and macrophage-derived chemokine (CCL22) by human fibroblasts from cornea, skin, and lung. J Allergy Clin Immunol 111:520-536, 2003
10. Gumbiner BM: Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 84:345-357, 1996
11. Hashimoto K: Regulation of keratinocyte function by growth factors. J Dermatol Sci 24 (Suppl. 1):s46-s50, 2000
12. Hirata H, Arima M, Cheng G, et al: Production of TARC and MDC by naive T cells in asthmatic patients. J Clin Immunol 23:34-45, 2003
13. Horikawa T, Nakayama T, Hikita I, et al: IFN-γ-inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/CCL22 in epidermal keratinocytes and their roles in atopic dermatitis. Int Immunol 14:767-773, 2002
14. Hu P, O'Keefe EJ, Rubenstein DS: Tyrosine phosphorylation of human keratinocyte β-catenin and plakoglobin reversibly regulates their binding to E-cadherin and α-catenin. J Invest Dermatol 117:1059-1067, 2001
15. Imai T, Nagira M, Takagi S, et al: Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokine thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol 11:82-88, 1999
16. Kakinuma T, Nakamura K, Wakugawa M, et al: Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity. J Allergy Clin Immunol 107:535-541, 2001
17. Kakinuma T, Nakamura K, Wakugawa M, et al: Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis. Clin Exp Immunol 127:270-273, 2002
18. Kakinuma T, Sugaya M, Nakamura K, Kaneko F, Wakugawa M, Matsushima K, Tamaki K: Thymus and activation-regulated chemokine (TARC/CCL17) in mycosis fungoides: Serum TARC levels reflect the disease activity of mycosis fungoides. J Am Acad Dermatol 48:23-30, 2003
19. Kanai T, Watanabe M, Hayashi A, et al: Regulatory effect of interleukin-4 and interleukin-13 on colon cancer cell adhesion. Br J Cancer 82:1717-1723, 2000
20. Kawasaki S, Takizawa H, Yoneyama H, et al: Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice. J Immunol 166:2055-2062, 2001
21. Kobayashi N, Terada N, Hamano N, Numata T, Konno A: Transepithelial migration of activated eosinophils induces a decrease of E-cadherin expression in cultured human nasal epithelial cells. Clin Exp Allergy 30:807-817, 2000
22. Kondo K, Kohno N, Yokoyama A, Hiwada K: Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines. Cancer Res 58:2014-2019, 1998
23. Kumagai N, Fukuda K, Nishida T: Synergistic effect of TNF-α and IL-4 on the expression of thymus- and activation-regulated chemokine in human corneal fibroblasts. Biochem Biophys Res Commun 279:1-5, 2000
24. Nelms K, Keegan AD, Zamorano J, Ryan JJ, Paul WE: The IL-4 receptor: Signaling mechanisms and biologic functions. Annu Rev Immunol 17:701-738, 1999
25. 125I-gamma interferon to cultured human keratinocytes. J Invest Dermatol 89:132-135, 1987
26. Pece S, Gutkind JS: Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation. J Biol Chem 275:41227-41233, 2000
27. Sekiya T, Miyamasu M, Imanishi M, et al: Inducible expression of a Th2-type CC chemokine thymus- and activation-regulated chemokine by human bronchial epithelial cells. J Immunol 165:2205-2213, 2000
28. Terada N, Nomura T, Kim WJ, et al: Expression of C-C chemokine TARC in human nasal mucosa and its regulatrion by cytokines. Clin Exp Allergy 31:1923-1931, 2001
29. Tsuda T, Tohyama M, Yamasaki K, et al: Lack of evidence for TARC/CCL17 production by normal human keratinocytes in vitro. J Dermatol Sci 31:37-42, 2003
30. Uchi H, Terao H, Koga T, Furue M: Cytokines and chemokines in the epidermis. J Dermatol Sci 24 (Suppl. 1):s29-s38, 2000
31. Vestergaard C, Yoneyama H, Murai M, et al: Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis like lesions. J Clin Invest 104:1097-1105, 1999
32. Vestergaard C, Bang K, Gesser B, Yoneyama H, Matsushima K, Larsen CG: A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA + CCR4 + lymphocytes into lesional atopic dermatitis skin. J Invest Dermatol 115:640-646, 2000
33. Vestergaard C, Kirstejn N, Gesser B, Mortensen JT, Matsushima K, Larsen CG: IL-10 augments the IFN-γ and TNF-α induced TARC production in HaCaT cells: A possible mechanism in the inflammatory reaction of atopic dermatitis. J Dermatol Sci 26:46-54, 2001
34. Vestweber D, Kelmer R: Identification of a putative cell adhesion domain of uvomorulin. EMBO J 16:3393-3398, 1985
35. Vulcano M, Albanesi C, Stoppacciaro A, et al: Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo. Eur J Immunol 31:812-822, 2001
36. Yoshie O, Imai T, Nomiyama H: Chemokines in immunity. Adv Immunol 78:57-110, 2001