Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis

Clinical and Experimental Immunology

Volumn 127, Issue 2, 2002, Pages 270-273

  Kakinuma, T ^a   Nakamura, K ^a   Wakugawa, M ^a   Mitsui, H ^a   Tada, Y ^a   Saeki, H ^a   Torii, H ^a   Komine, M ^a   Asahina, A ^a   Tamaki, K ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Atopic dermatitis; Disease activity; MDC

Indexed keywords

ANTIHISTAMINIC AGENT; CORTICOSTEROID; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERLEUKIN 2 RECEPTOR; MACROPHAGE DERIVED CHEMOKINE; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

ARTICLE; ATOPIC DERMATITIS; BLOOD ANALYSIS; CELL COUNT; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE SEVERITY; EOSINOPHIL; HUMAN; MACROPHAGE; MAJOR CLINICAL STUDY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PSORIASIS VULGARIS; SCORING SYSTEM; SOLUBILITY; TREATMENT OUTCOME;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ADRENAL CORTEX HORMONES; CHEMOKINES, CC; DERMATITIS, ATOPIC; E-SELECTIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTAMINE H1 ANTAGONISTS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; PSORIASIS; RECEPTORS, INTERLEUKIN-2; SEVERITY OF ILLNESS INDEX; SOLUBILITY;

EID: 0036128086     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2002.01727.x     Document Type: Article

References (22)

1. Diagnostic features of atopic dermatitis
2. Atopic dermatitis: Immunobiology and treatment with immune modulators
3. Differential in situ cytokine gene expression in acute vs. chronic atopic dermatitis
4. Responsiveness to interleukin 4 and interleukin 2 of peripheral blood cells in atopic dermatitis
5. Soluble intercellular adhesion molecule-1 and soluble E-selectin levels in patients with atopic dermatitis
6. Soluble E-selectin as a marker of disease activity in atopic dermatitis
7. Elevated levels of interleukin 2 receptor in sera of patients with atopic dermatitis and psoriasis
8. Chemokines. A new classification system and their role in immunity
9. Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells
10. Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4
11. Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine
12. Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions
13. Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity
14. Macrophage-derived chemokine production by activated human T cells in vitro and in vivo: Preferential association with the production of type 2 cytokines
15. Severity scoring of atopic dermatitis. The SCORAD index
16. Clinical validation and guidelines for the SCORAD index: Consensus report of the Europian Task Force on atopic dermatitis
17. Macrophage-derived chemokine is located to thymic medullary epithelial cells and is a chemoattractant for CD3 (+), CD4 (+), CD8 (low) thymocytes
18. Macrophage-derived chemokine induces human eosinophil chemotaxis in a CC chemokine receptor 3- and CC chemokine receptor 4-independent manner
19. Divergent effect of IL-4 and interferon gamma on macrophage-derived chemokine (MDC) production: An amplification circuit of polarized T helper 2 response
20. STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13
21. Selective upregulation of chemokine receptors CCR4 and CCR8 upon activation of polarized human type 2 T helper cells
22. Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation