Malignant Mammary Cells Acquire Independence from Extracellular Context for Regulation of Estrogen Receptor α

Clinical Cancer Research

Volumn 10, Issue 1, 2004, Pages

  Novaro, Virginia ^a   Radisky, Derek C ^a   Ramos Castro, Nancy E ^a   Weisz, Alessandro ^b   Bissell, Mina J ^a  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; ESTROGEN RECEPTOR ALPHA; LAMIN;

BASEMENT MEMBRANE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST CELL; BREAST EPITHELIUM; CANCER CELL; CONFERENCE PAPER; EXTRACELLULAR MATRIX; HUMAN; MAMMARY GLAND FUNCTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 1642487107     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-031209     Document Type: Conference Paper

References (40)

1. Bocchinfuso, W. P., Hively, W. P., Couse, J. F., Varmus, H. E., and Korach, K. S. A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-α. Cancer Res., 59: 1869-1876, 1999.
2. Lydon, J. P., DeMayo, F. J., Funk, C. R., Mani, S. K., Hughes, A. R., Montgomery, C. A., Jr., Shyamala, G., Conneely, O. M., and O'Malley, B. W. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev., 9: 2266-2278, 1995.
3. Shyamala, G., Chou, Y. C., Louie, S. G., Guzman, R. C., Smith, G. H., and Nandi, S. Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging. J. Steroid Biochem. Mol. Biol., 80: 137-148, 2002.
4. Shoker, B. S., Jarvis, C., Clarke, R. B., Anderson, E., Hewlett, J., Davies, M. P., Sibson, D. R., and Sloane, J. P. Estrogen receptor-positive proliferating cells in the normal and precancerous breast. Am. J. Pathol., 155: 1811-1815, 1999.
5. Russo, I. H., and Russo, J. Role of hormones in mammary cancer initiation and progression. J. Mammary Gland Biol. Neoplasia, 3: 49-61, 1998.
6. Lapidus, R. G., Nass, S. J., and Davidson, N. E. The loss of estrogen and progesterone receptor gene expression in human breast cancer. J. Mammary Gland Biol. Neoplasia, 3: 85-94, 1998.
7. Sommer, S., and Fuqua, S. A. Estrogen receptor and breast cancer. Semin. Cancer Biol., 11: 339-352, 2001.
8. Gustafsson, J. A., and Warner, M. Estrogen receptor β in the breast: role in estrogen responsiveness and development of breast cancer. J. Steroid Biochem. Mol. Biol., 74: 245-248, 2000.
9. Bissell, M. J., Weaver, V. M., Lelievre, S. A., Wang, F., Petersen, O. W., and Schmeichel, K. L. Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res., 59: 1757-1763s, 1999.
10. Hansen, R. K., and Bissell, M. J. Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones. Endocr. Relat. Cancer, 7: 95-113, 2000.
11. Haslam, S. Z., and Woodward, T. L. Host microenvironment in breast cancer development: epithelial-cell-stromal-cell interactions and steroid hormone action in normal and cancerous mammary gland. Breast Cancer Res., 5: 208-215, 2003.
12. Gudjonsson, T., Ronnov-Jessen, L., Villadsen, R., Rank, F., Bissell, M. J., and Petersen, O. W. Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J. Cell Sci., 115: 39-50, 2002.
13. Bissell, M. J., Radisky, D. C., Rizki, A., Weaver, V. M., and Petersen, O. W. The organizing principle: microenvironmental influences in the normal and malignant breast. Differentiation, 70: 537-546, 2002.
14. Parmar, H., Young, P., Emerman, J. T., Neve, R. M., Dairkee, S., and Cunha, G. R. A novel method for growing human breast epithelium in vivo using mouse and human mammary fibroblasts. Endocrinology, 143: 4886-4896, 2002.
15. Sternlicht, M. D., Lochter, A., Sympson, C. J., Huey, B., Rougier, J. P., Gray, J. W., Pinkel, D., Bissell, M. J., and Werb, Z. The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell, 98: 137-146, 1999.
16. Talhouk, R. S., Chin, J. R., Unemori, E. N., Werb, Z., and Bissell, M. J. Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture. Development, 112: 439-449, 1991.
17. Emerman, J. T., and Pitelka, D. R. Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes. In Vitro, 13: 316-328, 1977.
18. Yang, J., Liu, A., Dougherty, C., Chen, X., Guzman, R., and Nandi, S. Estrogen and progesterone receptors can be maintained in normal human breast epithelial cells in primary culture and after transplantation into nude mice. Oncol. Rep., 7: 17-21, 2000.
19. Novaro, V., Roskelley, C. D., and Bissell, M. J. Collagen-IV and laminin-1 regulate estrogen receptor (α) expression and function in mouse mammary epithelial cells. J. Cell Sci., 116: 2975-2986, 2003.
20. Nicolson, G. L., Dulski, K. M., and Trosko, J. E. Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells. Proc. Natl. Acad. Sci. USA, 85: 473-476, 1988.
21. Muthuswamy, S. K., Li, D., Lelievre, S., Bissell, M. J., and Brugge, J. S. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nat. Cell Biol., 3: 785-792, 2001.
22. Kurokawa, H., and Arteaga, C. L. ErbB (HER) Receptors can abrogate antiestrogen action in human breast cancer by multiple signaling mechanisms. Clin. Cancer Res., 9: 511S-515S, 2003.
23. Howlett, A. R., Bailey, N., Damsky, C., Petersen, O. W., and Bissell, M. J. Cellular growth and survival are mediated by β 1 integrins in normal human breast epithelium but not in breast carcinoma. J. Cell Sci., 108: 1945-1957, 1995.
24. Zutter, M. M., Sun, H., and Santoro, S. A. Altered integrin expression and the malignant phenotype: the contribution of multiple integrated integrin receptors. J. Mammary Gland Biol. Neoplasia, 3: 191-200, 1998.
25. Chrenek, M. A., Wong, P., and Weaver, V. M. Tumour-stromal interactions. Integrins and cell adhesions as modulators of mammary cell survival and transformation. Breast Cancer Res., 3: 224-229, 2001.
26. Wang, F., Weaver, V. M., Petersen, O. W., Larabell, C. A., Dedhar, S., Briand, P., Lupu, R., and Bissell, M. J. Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proc. Natl. Acad. Sci. USA, 95: 14821-14826, 1998.
27. Bissell, M. J., and Radisky, D. Putting tumours in context. Nat. Rev., 1: 46-54, 2001.
28. Giancotti, F. G., and Ruoslahti, E. Integrin signaling. Science (Wash. DC), 285: 1028-1032, 1999.
29. Liu, H., Radisky, D. C., Wang, F., and Bissell, M. J. Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in mammary epithelial tumor cells. J. Cell Biol., in press.
30. Nishida, K., Kitazawa, R., Mizuno, K., Maeda, S., and Kitazawa, S. Identification of regulatory elements of human α 6 integrin subunit gene. Biochem. Biophys. Res. Commun., 241: 258-263, 1997.
31. Lanzafame, S., Emmanuele, C., and Torrisi, A. Correlation of α 2 β 1 integrin expression with histological type and hormonal receptor status in breast carcinomas. Pathol. Res. Pract., 192: 1031-1038, 1996.
32. Fata, J. E., Ho, A. T., Leco, K. J., Moorehead, R. A., and Khokha, R. Cellular turnover and extracellular matrix remodeling in female reproductive tissues: functions of metalloproteinases and their inhibitors. Cell Mol. Life Sci., 57: 77-95, 2000.
33. Shyamala, G., Yang, X., Silberstein, G., Barcellos-Hoff, M. H., and Dale, E. Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands. Proc. Natl. Acad. Sci. USA, 95: 696-701, 1998.
34. Desprez, P. Y., Roskelley, C. D., Campisi, J., and Bissell, M. J. Isolation of functional cell lines from a mouse mammary epithelial cell strain: the importance of basement membrane and cell-cell interaction. Mol. Cell. Differ., 1: 99-110, 1993.
35. Lochter, A., Srebrow, A., Sympson, C. J., Terracio, N., Werb, Z., and Bissell, M. J. Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties. J. Biol. Chem., 272: 5607-5015, 1997.
36. Cicatiello, L., Cobellis, G., Addeo, R., Papa, M., Altucci, L., Sica, V., Bresciani, F., LeMeur, M., Lakshmi Kumar, V., Chambon, P., and Weisz, A. In vivo functional analysis of the mouse estrogen receptor gene promoter: A transgenic mouse model to study tissue-specific and developmental regulation of estrogen receptor gene transcription. Mol. Endocrinol., 9: 1077-1090, 1995.
37. Myers, C. A., Schmidhauser, C., Mellentin-Michelotti, J., Fragoso, G., Roskelley, C. D., Casperson, G., Mossi, R., Pujuguet, P., Hager, G., and Bissell, M. J. Characterization of BCE-1, a transcriptional enhancer regulated by prolactin and extracellular matrix and modulated by the state of histone acetylation. Mol. Cell Biol., 18: 2184-2195, 1998.
38. Stoecklin, E., Wissler, M., Schaetzle, D., Pfitzner, E., and Groner, B. Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family. J. Steroid Biochem. Mol. Biol., 69: 195-204, 1999.
39. Frasor, J., Barkai, U., Zhong, L., Fazleabas, A. T., and Gibori, G. PRL-induced ERα gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase. Mol. Endocrinol., 15: 1941-1952, 2001.
40. Lochter, A., Galosy, S., Muschler, J., Freedman, N., Werb, Z., and Bissell, M. J. Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J. Cell Biol., 139: 1861-1872, 1997.