TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain

Biochemical and Biophysical Research Communications

Volumn 317, Issue 1, 2004, Pages 230-234

  Matsumura, Takayuki ^a   Semba, Kentaro ^a   Azuma, Sakura ^a   Ikawa, Shuntaro ^b   Gohda, Jin ^a   Akiyama, Taishin ^a   Inoue, Jun Ichiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

IL 1; IRAK 1; Negative regulator; NF B; TIFA; TLR; TRAF

Indexed keywords

BINDING PROTEIN; PROTEIN; TRAF INTERACTING PROTEIN WITH A FORKHEAD ASSOCIATED DOMAIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONFORMATIONAL TRANSITION; HUMAN; IMMUNOPRECIPITATION; INFLAMMATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STIMULATION;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL LINE; GENE EXPRESSION; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PRECIPITIN TESTS; PROTEINS; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSFECTION; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 1642463450     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.03.030     Document Type: Article

References (17)

1. Arch R.H., Gedrich R.W., Thompson C.B. Tumor necrosis factor receptor-associated factors (TRAFs) - a family of adapter proteins that regulates life and death. Genes Dev. 12:1998;2821-2830.
2. Inoue J., Ishida T., Tsukamoto N., Kobayashi N., Naito A., Azuma S., Yamamoto T. Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling. Exp. Cell Res. 254:2000;14-24.
3. Cao Z., Xiong J., Takeuchi M., Kurama T., Goeddel D.V. TRAF6 is a signal transducer for interleukin-1. Nature. 383:1996;443-446.
4. Ishida T., Mizushima S., Azuma S., Kobayashi N., Tojo T., Suzuki K., Aizawa S., Watanabe T., Mosialos G., Kieff E., Yamamoto T., Inoue J. Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J. Biol. Chem. 271:1996;28745-28748.
5. Lomaga M.A., Yeh W.C., Sarosi I., Duncan G.S., Furlonger C., Ho A., Morony S., Capparelli C., Van G., Kaufman S., van der Heiden A., Itie A., Wakeham A., Khoo W., Sasaki T., Cao Z., Penninger J.M., Paige C.J., Lacey D.L., Dunstan C.R., Boyle W.J., Goeddel D.V., Mak T.W. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev. 13:1999;1015-1024.
6. Naito A., Azuma S., Tanaka S., Miyazaki T., Takaki S., Takatsu K., Nakao K., Nakamura K., Katsuki M., Yamamoto T., Inoue J. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells. 4:1999;353-362.
7. Kobayashi N., Kadono Y., Naito A., Matsumoto K., Yamamoto T., Tanaka S., Inoue J. Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO J. 20:2001;1271-1280.
8. Yoshida H., Naito A., Inoue J., Satoh M., Santee-Cooper S.M., Ware C.F., Togawa A., Nishikawa S. Different cytokines induce surface lymphotoxin-. αβ on IL-7 receptor-α cells that differentially engender lymph nodes and Peyer's patches Immunity. 17:2002;823-833.
9. Naito A., Yoshida H., Nishioka E., Satoh M., Azuma S., Yamamoto T., Nishikawa S., Inoue J. TRAF6-deficient mice display hypohidrotic ectodermal dysplasia. Proc. Natl. Acad. Sci. USA. 99:2002;8766-8771.
10. Kanamori M., Suzuki H., Saito R., Muramatsu M., Hayashizaki Y. T2BP, a novel TRAF2 binding protein, can activate NF-κB and AP-1 without TNF stimulation. Biochem. Biophys. Res. Commun. 290:2002;1108-1113.
11. Takatsuna H., Kato H., Gohda J., Akiyama T., Moriya A., Okamoto Y., Yamagata Y., Otsuka M., Umezawa K., Semba K., Inoue J. Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling. J. Biol. Chem. 278:2003;12144-12150.
12. Hofmann K., Bucher P. The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors. Trends Biochem. Sci. 20:1995;347-349.
13. Li J., Lee G.I., Van Doren S.R., Walker J.C. The FHA domain mediates phosphoprotein interactions. J. Cell Sci. 113(Pt. 23):2000;4143-4149.
14. Yaffe M.B., Cantley L.C. Signal transduction. Grabbing phosphoproteins. Nature. 402:1999;30-31.
15. Ishida T., Tojo T., Aoki T., Kobayashi N., Ohishi T., Watanabe T., Yamamoto T., Inoue J. TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling. Proc. Natl. Acad. Sci. USA. 93:1996;9437-9442.
16. Baud V., Liu Z.G., Bennett B., Suzuki N., Xia Y., Karin M. Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev. 13:1999;1297-1308.
17. Wang C., Deng L., Hong M., Akkaraju G.R., Inoue J., Chen Z.J. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature. 412:2001;346-351.