Flexibility Exists in the Region of [A6-A11, A7-B7] Disulfide Bonds during Insulin Precursor Folding

Journal of Biochemistry

Volumn 135, Issue 1, 2004, Pages 1-6

  Liu, Ying ^a   Wang, Zhao Hui ^a   Tang, Jian Guo ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Disulfide bond; Flexibility; Proinsulin analogue; Protein folding; Refolding yield

Indexed keywords

BIOSYNTHETIC HUMAN PROINSULIN; CYSTEINE; MUTANT PROTEIN; PROINSULIN; SERINE; SOMATOMEDIN C; THIOL GROUP; TRIFLUOROACETIC ACID;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DELETION MUTANT; DISULFIDE BOND; ENZYME ACTIVITY; GENE; HPI GENE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PROTEIN FOLDING; RECEPTOR BINDING; THERMODYNAMICS; THERMOSTABILITY; WILD TYPE;

DISULFIDES; INSULIN; INSULIN-LIKE GROWTH FACTOR I; PLIABILITY; PROINSULIN; PROTEIN BINDING; PROTEIN FOLDING;

EID: 1642422219     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvg134     Document Type: Article

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