Base Excision and DNA Binding Activities of Human Alkyladenine DNA Glycosylase Are Sensitive to the Base Paired with a Lesion

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 13379-13387

  Abner, Clint W ^a   Lau, Albert Y ^b   Ellenberger, Tom ^b   Bloom, Linda B ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOCHEMISTRY; SUBSTRATES;

BINDING ASSAYS; DNA BINDING ACTIVITIES;

DNA;

1,N6 ETHENOADENINE; 6 O METHYLGUANINE; 8 HYDROXYGUANINE; ADENINE; DNA BASE; DNA GLYCOSYLTRANSFERASE; GUANINE; HYPOXANTHINE; UNCLASSIFIED DRUG; 1,N(6) ETHENOADENOSINE; 1,N(6)-ETHENOADENOSINE; 3 METHYLADENINE DEOXYRIBONUCLEIC ACID GLYCOSYLASE; 3-METHYLADENINE-DNA GLYCOSYLASE; ADENOSINE; DNA; DRUG DERIVATIVE; GLYCOSIDASE; OLIGODEOXYRIBONUCLEOTIDE;

ARTICLE; BASE PAIRING; BINDING AFFINITY; BINDING ASSAY; DNA BINDING; DNA DAMAGE; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; KINETICS; PRIORITY JOURNAL; CHEMISTRY; CONFORMATION; DNA REPAIR; HUMAN; HYDROGEN BOND; METABOLISM; NUCLEOTIDE SEQUENCE;

ADENOSINE; BASE PAIRING; BASE SEQUENCE; DNA; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; HUMANS; HYDROGEN BONDING; HYPOXANTHINE; KINETICS; N-GLYCOSYL HYDROLASES; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; SUBSTRATE SPECIFICITY;

EID: 0035918230     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010641200     Document Type: Article

References (34)

1. Mol, C. D., Parikh, S. S., Putnam, C. D., Lo, T. P., and Tainer, J. A. (1999) Annu. Rev. Biophys. Biomol. Struct. 28, 101-128
2. McCullough, A. K., Dodson, M. L., and Lloyd, R. S. (1999) Annu. Rev. Biochem. 68, 255-285
3. Hollis, T., Lau, A., and Ellenberger, T. (2000) Mutat. Res. 460, 201-210
4. Stivers, J. T., Pankiewicz, K. W., and Watanabe, K. A. (1999) Biochemistry 38, 952-963
5. Chakravarti, D., Ibeanu, G. C., Tano, K., and Mitra, S. (1991) J. Biol. Chem. 266, 15710-15715
6. Samson, L., Derfler, B., Boosalis, M., and Call, K. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 9127-9131
7. O'Connor, T. R. (1993) Nucleic Acids Res. 21, 5561-5569
8. Dosanjh, M. K., Roy, R., Mitra, S., and Singer, B. (1994) Biochemistry 33, 1624-1628
9. Saparbaev, M., Kleibl, K., and Laval, J. (1995) Nucleic Acids Res. 23, 3750-3755
10. Roy, R., Kennel, S. J., and Mitra, S. (1996) Carcinogenesis 17, 2177-2182
11. Asaeda, A., Ide, H., Asagoshi, K., Matsuyama, S., Tano, K., Murakami, A., Takamori, Y., and Kubo, K. (2000) Biochemistry 39, 1959-1965
12. Dosanjh, M. K., Chenna, A., Kim, E., Fraenkel-Conrat, H., Samson, L., and Singer, B. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1024-1028
13. Bessho, T., Roy, R., Yamamoto, K., Kasai, H., Nishimura, S., Tano, K., and Mitra, S. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8901-8904
14. Saparbaev, M., and Laval, J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 5873-5877
15. Miao, F., Bouziane, M., and O'Connor, T. R. (1998) Nucleic Acids Res. 26, 4034-4041
16. Berdal, K. G., Johansen, R. F., and Seeberg, E. (1998) EMBO J. 17, 363-367
17. Wyatt, M. D., Allan, J. M., Lau, A. Y., Ellenberger, T. E., and Samson, L. D. (1999) Bioessays 21, 668-676
18. Fasman, G. (ed). (1975) Handbook of Biochemistry: Nucleic Acids, Vol. 1, p. 589, CRC Press, Inc., Boca Raton, FL
19. Secrist, J. A., III, Barrio, J. R., Leonard, N. J., and Weber, G. (1972) Biochemistry 11, 3499-3506
20. Roy, R., Biswas, T., Hazra, T. K., Roy, G., Grabowski, D. T., Izumi, T., Srinivasan, G., and Mitra, S. (1998) Biochemistry 37, 580-589
21. Lau, A. Y., Schärer, O. D., Samson, L., Verdine, G. L., and Ellenberger, T. (1998) Cell 95, 249-258
22. Porello, S. L., Leyes, A. E., and David, S. S. (1998) Biochemistry 37, 14756-14764
23. Waters, T. R., and Swann, P. F. (1998) J. Biol. Chem. 273, 20007-20014
24. Petronzelli, F., Riccio, A., Markham, G. D., Seeholzer, S. H., Stoerker, J., Genuardi, M., Yeung, A. T., Matsumoto, Y., and Bellacosa, A. (2000) J. Biol. Chem. 275, 32422-32429
25. Wyatt, M. D., and Samson, L. D. (2000) Carcinogenesis 21, 901-908
26. Lau, A. Y., Wyatt, M. D., Glassner, B. J., Samson, L. D., and Ellenberger, T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 13573-13578
27. Parikh, S. S., Mol, C. D., Slupphaug, G., Bharati, S., Krokan, H. E., and Tainer, J. A. (1998) EMBO J. 17, 5214-5226
28. Parikh, S. S., Walcher, G., Jones, G. D., Slupphaug, G., Krokan, H. E., Blackburn, G. M., and Tainer, J. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5083-5088
29. Savva, R., McAuley-Hecht, K., Brown, T., and Pearl, L. (1995) Nature 373, 487-493
30. Mol, C. D., Arvai, A. S., Slupphaug, G., Kavli, B., Alseth, I., Krokan, H. E., and Tainer, J. A. (1995) Cell 80, 869-878
31. Labahn, J., Schärer, O. D., Long, A., Ezaz-Nikpay, K., Verdine, G. L., and Ellenberger, T. E. (1996) Cell 86, 321-329
32. Yamagata, Y., Kato, M., Odawara, K., Tokuno, Y., Nakashima, Y., Matsushima, M., Yasumura, K., Tomita, K., Ihara, K., Fujii, Y., Nakabeppu, Y., Sekiguchi, M., and Fujii, S. (1996) Cell 86, 311-319
33. Kouchakdjian, M., Eisenberg, M., Yarema, K., Basu, A., Essigmann, J., and Patel, D. J. (1991) Biochemistry 30, 1820-1828
34. Kartalou, M., Samson, L. D., and Essigmann, J. M. (2000) Biochemistry 39, 8032-8038