Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation

Molecular Brain Research

Volumn 123, Issue 1-2, 2004, Pages 27-36

  Galigniana, Mario D ^a   Harrell, Jennifer M ^a   Housley, Paul R ^b   Patterson, Cam ^c   Fisher, Stephen K ^a   Pratt, William B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Cellular and molecular biology; CHIP; Cytoskeleton transport and membrane targeting; Geldanamycin; GFP; Glucocorticoid receptor; GR; Green fluorescent protein; Heat shock protein; hsp; hsp90; Proteasomal degradation; Protein trafficking

Indexed keywords

CARBOXYL TERMINUS OF HEAT SHOCK PROTEIN 70 INTERACTING PROTEIN; CHAPERONE; DEXAMETHASONE; GELDANAMYCIN; GLUCOCORTICOID RECEPTOR; GREEN FLUORESCENT PROTEIN; HEAT SHOCK PROTEIN 90; PROTEASOME; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CHIMERA; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DYNAMICS; ENZYME DEGRADATION; NERVE CELL; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN TRANSPORT; RAT;

AXONS; BENZOQUINONES; CELL COMPARTMENTATION; CELL LINE, TUMOR; CELL NUCLEUS; CYSTEINE ENDOPEPTIDASES; CYTOPLASM; DENDRITES; DEXAMETHASONE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MACROMOLECULAR SUBSTANCES; MULTIENZYME COMPLEXES; NEURITES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; QUINONES; RECEPTORS, GLUCOCORTICOID; RECOMBINANT FUSION PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 1642392035     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2003.12.015     Document Type: Article

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