Single-channel activity of L-type Ca2+ channels reconstituted with the β2c subunit cloned from the rat heart

European Journal of Pharmacology

Volumn 487, Issue 1-3, 2004, Pages 37-45

  Kamada, Yasuhiro ^a   Yamada, Yoichi ^a   Yamakage, Michiaki ^a   Nagashima, Masato ^a   Tsutsuura, Masaaki ^a   Kobayashi, Takeshi ^a   Seki, Sumihiko ^a   Namiki, Akiyoshi ^a   Tohse, Noritsugu ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

2c Subunit; L type Ca2+ channel; Modal gating behavior; Single channel analysis

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2C ADRENERGIC RECEPTOR; CALCIUM; CALCIUM CHANNEL L TYPE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CELL ACTIVITY; CELL CLONE; CHANNEL GATING; CONTROLLED STUDY; HEART MUSCLE CELL; INTERMETHOD COMPARISON; NONHUMAN; PRIORITY JOURNAL; PROTEIN VARIANT; RAT;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; ANIMALS; CALCIUM CHANNEL AGONISTS; CALCIUM CHANNELS, L-TYPE; CERCOPITHECUS AETHIOPS; COS CELLS; ELECTROPHYSIOLOGY; HEART; ION CHANNEL GATING; MYOCARDIUM; RATS; TRANSFECTION;

EID: 1642387730     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.01.016     Document Type: Article

References (21)

1. Bers D.M. Cardiac excitation-contraction coupling. Nature. 415:2002;198-205.
2. Birnbaumer L., Qin N., Olcese R., Tareilus E., Platano D., Costantin J., Stefani E. Structures and functions of calcium channel β subunits. J. Bioenerg. Biomembranes. 30:1998;357-375.
3. 2+ channels. Annu. Rev. Cell Dev. Biol. 16:2000;521-555.
4. 2+ channel β subunits revealed by their expression in adult rat heart cells. J. Physiol. 541:2002;435-452.
5. 2+ channels. J. Physiol. 507:1998;93-103.
6. Hess P., Lansman J.B., Tsien R.W. Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature. 311:1984;538-544.
7. 2+ channel diversity. Annu. Rev. Neurosci. 17:1994;399-418.
8. Hofmann F., Lacinova L., Klugbauer N. Voltage-dependent calcium channels: from structure to function. Rev. Physiol., Biochem. Pharmacol. 139:1999;35-87.
9. Isenberg G., Klockner U. Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium" Pflugers Arch. 395:1982;6-18.
10. 2+ channel. Nature. 352:1991;527-530.
11. Masuda H., Sumii K., Sperelakis N. Long openings of calcium channels in fetal rat ventricular cardiomyocytes. Pflugers Arch. 429:1995;595-597.
12. Perez-Reyes E., Schneider T. Molecular biology of calcium channels. Kidney Int. 48:1995;1111-1124.
13. Perez-Reyes E., Castellano A., Kim H.S., Bertrand P., Baggstrom E., Lacerda A.E., Wei X.Y., Birnbaumer L. Cloning and expression of a cardiac/brain β subunit of the L-type calcium channel. J. Biol. Chem. 267:1992;1792-1797.
14. 2+-dependent inactivation of L-type calcium channels. Neuron. 22:1999;549-558.
15. Pietrobon D., Hess P. Novel mechanism of voltage-dependent gating in L-type calcium channels. Nature. 346:1990;651-655.
16. 2+ channel β subunit caused by palmitoylation. Proc. Natl. Acad. Sci. U. S. A. 95:1998;4690-4695.
17. Tohse N. Calcium-sensitive delayed rectifier potassium current in guinea pig ventricular cells. Am. J. Physiol. 258:1990;H1200-H1207.
18. 2+ channels in embryonic chick heart cells. Circ. Res. 71:1992;376-384.
19. 2+ channel modulation by recombinant auxiliary β subunits expressed in young adult heart cells. Circ. Res. 86:2002;175-184.
20. 2 subunit from rat heart. J. Biol. Chem. 276:2001;47163-47170.
21. Yue D.T., Herzig S., Marban E. β-Adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes. Proc. Natl. Acad. Sci. U. S. A. 87:1990;753-757.