메뉴 건너뛰기




Volumn 286, Issue 4 55-4, 2004, Pages

Differential regulation of PHEX expression in bone and parathyroid gland by chronic renal insufficiency and 1,25-dihydroxyvitamin D3

Author keywords

Endopeptidase; Hyperphosphatemia; Parathyroid hormone

Indexed keywords

CALCITRIOL; GENE PRODUCT; PROTEIN PHEX; UNCLASSIFIED DRUG;

EID: 1642379621     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00321.2003     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 12244263475 scopus 로고    scopus 로고
    • Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression
    • Bai X, Miao D, Panda D, Grady S, McKee MD, Goltzman D, and Karaplis AC. Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression. Mol Endocrinol 16: 2913-2925, 2002.
    • (2002) Mol Endocrinol , vol.16 , pp. 2913-2925
    • Bai, X.1    Miao, D.2    Panda, D.3    Grady, S.4    McKee, M.D.5    Goltzman, D.6    Karaplis, A.C.7
  • 2
    • 0030938927 scopus 로고    scopus 로고
    • Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice
    • Beck L, Soumounou Y, Martel J, Krishnamurthy G, Gauthier C, Goodyer C, and Tenenhouse HS. Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice. J Clin Invest 99: 1200-1209, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 1200-1209
    • Beck, L.1    Soumounou, Y.2    Martel, J.3    Krishnamurthy, G.4    Gauthier, C.5    Goodyer, C.6    Tenenhouse, H.S.7
  • 3
    • 0032781733 scopus 로고    scopus 로고
    • PHEX expression in parathyroid gland and PTH dysregulation in X-linked hypophosphatemia
    • Blydt-Hansen TD, Tenenhouse HS, and Goodyer P. PHEX expression in parathyroid gland and PTH dysregulation in X-linked hypophosphatemia. Pediatr Nephrol 13: 607-611, 1999.
    • (1999) Pediatr Nephrol , vol.13 , pp. 607-611
    • Blydt-Hansen, T.D.1    Tenenhouse, H.S.2    Goodyer, P.3
  • 7
    • 0033305526 scopus 로고    scopus 로고
    • Propara-thyroid hormone processing by the proprotein convertase-7: Comparison with furin and assessment of modulation of parathyroid convertase messenger ribonucleic acid levels by calcium and 1,25-dihydroxyvitamin D
    • Canaff L, Bennett HPJ, Hou Y, Seidah NG, and Hendy GN. Propara-thyroid hormone processing by the proprotein convertase-7: comparison with furin and assessment of modulation of parathyroid convertase messenger ribonucleic acid levels by calcium and 1,25-dihydroxyvitamin D. Endocrinology 140: 3633-3642, 1999.
    • (1999) Endocrinology , vol.140 , pp. 3633-3642
    • Canaff, L.1    Bennett, H.P.J.2    Hou, Y.3    Seidah, N.G.4    Hendy, G.N.5
  • 8
    • 0030586965 scopus 로고    scopus 로고
    • cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone
    • Du L, Desbarats M, Viel J, Glorieux FH, Cawthorn C, and Ecarot B. cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone. Genomics 36: 22-28, 1996.
    • (1996) Genomics , vol.36 , pp. 22-28
    • Du, L.1    Desbarats, M.2    Viel, J.3    Glorieux, F.H.4    Cawthorn, C.5    Ecarot, B.6
  • 9
    • 0036838193 scopus 로고    scopus 로고
    • Role of abnormal neutral endopeptidase-like activities in Hyp mouse bone cells in renal phosphate transport
    • Dubois SG, Ruchon AF, Delalandre A, Boileau G, and Lajeunesse D. Role of abnormal neutral endopeptidase-like activities in Hyp mouse bone cells in renal phosphate transport. Am J Physiol Cell Physiol 283: C1414-C1421, 2002.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Dubois, S.G.1    Ruchon, A.F.2    Delalandre, A.3    Boileau, G.4    Lajeunesse, D.5
  • 10
    • 0032963140 scopus 로고    scopus 로고
    • 3 down-regulates expression of Phex, a marker of the mature osteoblast
    • 3 down-regulates expression of Phex, a marker of the mature osteoblast. Endocrinology 140: 1192-1199, 1999.
    • (1999) Endocrinology , vol.140 , pp. 1192-1199
    • Ecarot, B.1    Desbarats, M.2
  • 11
    • 0026513193 scopus 로고
    • Defective bone formation by Hyp mouse bone cells transplanted into normal mice: Evidence in favor of an intrinsic osteoblast defect
    • Ecarot B, Glorieux FH, Desbarats M, Travers R, and Labelle L. Defective bone formation by Hyp mouse bone cells transplanted into normal mice: evidence in favor of an intrinsic osteoblast defect. J Bone Miner Res 7: 215-220, 1992.
    • (1992) J Bone Miner Res , vol.7 , pp. 215-220
    • Ecarot, B.1    Glorieux, F.H.2    Desbarats, M.3    Travers, R.4    Labelle, L.5
  • 12
    • 0035723074 scopus 로고    scopus 로고
    • Evidence for a PTH-independent humoral mechanism in post-transplant hypophosphatemia and phosphaturia
    • Green J, Debby H, Lederer E, Levi M, Zajicek HK, and Bick T. Evidence for a PTH-independent humoral mechanism in post-transplant hypophosphatemia and phosphaturia. Kidney Int 60: 1182-1196, 2001.
    • (2001) Kidney Int , vol.60 , pp. 1182-1196
    • Green, J.1    Debby, H.2    Lederer, E.3    Levi, M.4    Zajicek, H.K.5    Bick, T.6
  • 14
    • 0032743354 scopus 로고    scopus 로고
    • Effects of Npt2 gene ablation and low-phosphate diet on renal Na/phosphate cotransport and cotransporter gene expression
    • Hoag HM, Martel J, Gauthier C, and Tenenhouse HS. Effects of Npt2 gene ablation and low-phosphate diet on renal Na/phosphate cotransport and cotransporter gene expression. J Clin Invest 104: 679-686, 1999.
    • (1999) J Clin Invest , vol.104 , pp. 679-686
    • Hoag, H.M.1    Martel, J.2    Gauthier, C.3    Tenenhouse, H.S.4
  • 16
    • 0029160578 scopus 로고
    • A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets
    • HYP Consortium. A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet 11: 130-136, 1995.
    • (1995) Nat Genet , vol.11 , pp. 130-136
    • Consortium, H.Y.P.1
  • 17
    • 0018485136 scopus 로고
    • Radiographic evidence of craniofacial and dental abnormalities in the X-linked hypophosphatemic mouse
    • Iorio RJ, Bell WA, Meyer MH, and Meyer RA Jr. Radiographic evidence of craniofacial and dental abnormalities in the X-linked hypophosphatemic mouse. Ann Dent 38: 31-37, 1979.
    • (1979) Ann Dent , vol.38 , pp. 31-37
    • Iorio, R.J.1    Bell, W.A.2    Meyer, M.H.3    Meyer Jr., R.A.4
  • 19
    • 0029152819 scopus 로고
    • Parathyroid hormone gene expression in hypophosphatemic rats
    • Kilav R, Silver J, and Naveh-Many T. Parathyroid hormone gene expression in hypophosphatemic rats. J Clin Invest 96: 327-333, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 327-333
    • Kilav, R.1    Silver, J.2    Naveh-Many, T.3
  • 20
    • 0029385433 scopus 로고
    • Inhibitors of renal epithelial phosphate transport in tumor-induced osteomalacia and uremia
    • Kumar R, Haugen JD, Wieben ED, Londowski JM, and Cai Q. Inhibitors of renal epithelial phosphate transport in tumor-induced osteomalacia and uremia. Proc Assoc Am Physicians 107: 296-305, 1995.
    • (1995) Proc Assoc Am Physicians , vol.107 , pp. 296-305
    • Kumar, R.1    Haugen, J.D.2    Wieben, E.D.3    Londowski, J.M.4    Cai, Q.5
  • 22
    • 0034878896 scopus 로고    scopus 로고
    • Cloning and characterization of the proximal murine Phex promoter
    • Liu S, Guo R, and Quarles LD. Cloning and characterization of the proximal murine Phex promoter. Endocrinology 142: 3987-3995, 2001.
    • (2001) Endocrinology , vol.142 , pp. 3987-3995
    • Liu, S.1    Guo, R.2    Quarles, L.D.3
  • 23
    • 0036479315 scopus 로고    scopus 로고
    • Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype
    • Liu S, Guo R, Tu Q, and Quarles LD. Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype. J Biol Chem 277: 3686-3697, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 3686-3697
    • Liu, S.1    Guo, R.2    Tu, Q.3    Quarles, L.D.4
  • 25
    • 0024330123 scopus 로고
    • Parabiosis suggests a humoral factor is involved in X-linked hypophosphatemia in mice
    • Meyer RA Jr, Meyer MH, and Gray RW. Parabiosis suggests a humoral factor is involved in X-linked hypophosphatemia in mice. J Bone Miner Res 4: 493-500, 1989.
    • (1989) J Bone Miner Res , vol.4 , pp. 493-500
    • Meyer Jr., R.A.1    Meyer, M.H.2    Gray, R.W.3
  • 26
    • 0024310077 scopus 로고
    • The renal phosphate transport defect in normal mice parabiosed to X-linked hypophosphatemic mice persists after parathyroidectomy
    • Meyer RA Jr, Tenenhouse HS, Meyer MH, and Klugerman AH. The renal phosphate transport defect in normal mice parabiosed to X-linked hypophosphatemic mice persists after parathyroidectomy. J Bone Miner Res 4: 523-532, 1989.
    • (1989) J Bone Miner Res , vol.4 , pp. 523-532
    • Meyer Jr., R.A.1    Tenenhouse, H.S.2    Meyer, M.H.3    Klugerman, A.H.4
  • 27
    • 0035107364 scopus 로고    scopus 로고
    • Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition
    • Miao D, Bai X, Panda D, McKee M, Karaplis A, and Goltzman D. Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition. Endocrinology 142: 926-939, 2001.
    • (2001) Endocrinology , vol.142 , pp. 926-939
    • Miao, D.1    Bai, X.2    Panda, D.3    McKee, M.4    Karaplis, A.5    Goltzman, D.6
  • 28
    • 0031696056 scopus 로고    scopus 로고
    • Disparate effects of mild, moderate, and severe secondary hyperparathyroidism on cancellous and cortical bone in rats with chronic renal insufficiency
    • Miller MA, Chin J, Miller SC, and Fox J. Disparate effects of mild, moderate, and severe secondary hyperparathyroidism on cancellous and cortical bone in rats with chronic renal insufficiency. Bone 23: 257-266, 1998.
    • (1998) Bone , vol.23 , pp. 257-266
    • Miller, M.A.1    Chin, J.2    Miller, S.C.3    Fox, J.4
  • 29
    • 0033930433 scopus 로고    scopus 로고
    • The effects of bone marrow transplantation on X-linked hypophosphatemic mice
    • Miyamura T, Tanaka H, Inoue M, Ichinose Y, and Seino Y. The effects of bone marrow transplantation on X-linked hypophosphatemic mice. J Bone Miner Res 15: 1451-1458, 2000.
    • (2000) J Bone Miner Res , vol.15 , pp. 1451-1458
    • Miyamura, T.1    Tanaka, H.2    Inoue, M.3    Ichinose, Y.4    Seino, Y.5
  • 30
    • 0026691973 scopus 로고
    • Cross-transplantation of kidneys in normal and Hyp mice: Evidence that the Hyp phenotype is unrelated to an intrinsic renal defect
    • Nesbitt T, Coffman TM, Griffiths R, and Drezner MK. Cross-transplantation of kidneys in normal and Hyp mice: evidence that the Hyp phenotype is unrelated to an intrinsic renal defect. J Clin Invest 89: 1453-1459, 1992.
    • (1992) J Clin Invest , vol.89 , pp. 1453-1459
    • Nesbitt, T.1    Coffman, T.M.2    Griffiths, R.3    Drezner, M.K.4
  • 31
    • 0027327616 scopus 로고
    • Parental origin of mutant allele does not explain absence of gene dose in X-linked Hyp mice
    • Qiu ZQ, Tenenhouse HS, and Scriver CR. Parental origin of mutant allele does not explain absence of gene dose in X-linked Hyp mice. Genet Res 62: 39-43, 1993.
    • (1993) Genet Res , vol.62 , pp. 39-43
    • Qiu, Z.Q.1    Tenenhouse, H.S.2    Scriver, C.R.3
  • 32
    • 0942268149 scopus 로고    scopus 로고
    • Effect of gene dose and parental origin on bone histomorphometry in X-linked Hyp mice
    • Qiu ZQ, Travers R, Rauch F, Glorieux FH, Scriver CR, and Tenenhouse HS. Effect of gene dose and parental origin on bone histomorphometry in X-linked Hyp mice. Bone 34: 134-139, 2004.
    • (2004) Bone , vol.34 , pp. 134-139
    • Qiu, Z.Q.1    Travers, R.2    Rauch, F.3    Glorieux, F.H.4    Scriver, C.R.5    Tenenhouse, H.S.6
  • 35
    • 0025202286 scopus 로고
    • Conserved loci on the X chromosome confer phosphate homeostasis in mice and humans
    • Scriver CR and Tenenhouse HS. Conserved loci on the X chromosome confer phosphate homeostasis in mice and humans. Genet Res 56: 141-152, 1990.
    • (1990) Genet Res , vol.56 , pp. 141-152
    • Scriver, C.R.1    Tenenhouse, H.S.2
  • 36
    • 0031008584 scopus 로고    scopus 로고
    • In vivo regulation of chromogranin A messenger ribonucleic acid in the parathyroid by 1,25-dihydroxyvitamin D: Studies in normal rats and in chronic renal insufficiency
    • Soliman E, Canaff L, Fox J, and Hendy GN. In vivo regulation of chromogranin A messenger ribonucleic acid in the parathyroid by 1,25-dihydroxyvitamin D: studies in normal rats and in chronic renal insufficiency. Endocrinology 138: 2596-2600, 1997.
    • (1997) Endocrinology , vol.138 , pp. 2596-2600
    • Soliman, E.1    Canaff, L.2    Fox, J.3    Hendy, G.N.4
  • 37
    • 0032893855 scopus 로고    scopus 로고
    • X-linked hypophosphatemia: A homologous disorder in humans and mice
    • Tenenhouse HS. X-linked hypophosphatemia: a homologous disorder in humans and mice. Nephrol Dial Transplant 14: 333-341, 1999.
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 333-341
    • Tenenhouse, H.S.1
  • 38
    • 0002701258 scopus 로고    scopus 로고
    • Mendelian hypophosphatemias
    • edited by Scriver CR, Beaudet AL, Sly WS, and Valle D. New York: McGraw-Hill
    • Tenenhouse HS and Econs MJ. Mendelian hypophosphatemias. In: The Metabolic and Molecular Bases of Inherited Disease, edited by Scriver CR, Beaudet AL, Sly WS, and Valle D. New York: McGraw-Hill, 2001, p. 5039-5067.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 5039-5067
    • Tenenhouse, H.S.1    Econs, M.J.2
  • 40
    • 0030899822 scopus 로고    scopus 로고
    • Mammalian membrane metallopeptidases: NEP, ECE, KELL and PEX
    • Turner AJ and Tanzawa K. Mammalian membrane metallopeptidases: NEP, ECE, KELL and PEX. FASEB J 11: 355-364, 1997.
    • (1997) FASEB J , vol.11 , pp. 355-364
    • Turner, A.J.1    Tanzawa, K.2
  • 41
    • 0032810056 scopus 로고    scopus 로고
    • Evidence for Phex haploinsufficiency in murine X-linked hypophosphatemia
    • Wang LQ, Du LS, and Ecarot B. Evidence for Phex haploinsufficiency in murine X-linked hypophosphatemia. Mamm Genome 10: 385-389, 1999.
    • (1999) Mamm Genome , vol.10 , pp. 385-389
    • Wang, L.Q.1    Du, L.S.2    Ecarot, B.3
  • 42
    • 0141525564 scopus 로고    scopus 로고
    • Serum FGF23 levels in normal and disordered phosphorus homeostasis
    • Weber TJ, Liu S, Indridason OS, and Quarles LD. Serum FGF23 levels in normal and disordered phosphorus homeostasis. J Bone Miner Res 18: 1227-1234, 2003.
    • (2003) J Bone Miner Res , vol.18 , pp. 1227-1234
    • Weber, T.J.1    Liu, S.2    Indridason, O.S.3    Quarles, L.D.4
  • 43
    • 0029798574 scopus 로고    scopus 로고
    • X-linked hypophosphatemia: A search for gender, race, anticipation, or parent of origin effects on disease expression in children
    • Whyte MP, Schrank FW, and Armamento-Villareal R. X-linked hypophosphatemia: a search for gender, race, anticipation, or parent of origin effects on disease expression in children. J Clin Endocrinol Metab 81: 4075-4080, 1996.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4075-4080
    • Whyte, M.P.1    Schrank, F.W.2    Armamento-Villareal, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.