P38 mitogen activated protein kinase is involved in the downregulation of granulocyte CXC chemokine receptors 1 and 2 during human endotoxemia

Journal of Clinical Immunology

Volumn 24, Issue 1, 2004, Pages 37-41

  Van Den Blink, Bernt ^a   Branger, Judith ^a   Weijer, Sebastiaan ^a   Gupta, Abhya ^b   Van Deventer, Sander J H ^a   Peppelenbosch, Maikel P ^a   Van Der Poll, Tom ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Chemokines; Endotoxin; Granulocytes; Interleukin 8; Lipopolysaccharide

Indexed keywords

BIRB 796 BS; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CYTOKINE; CYTOKINE RECEPTOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 8; INTERLEUKIN 8 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PLACEBO; UNCLASSIFIED DRUG;

ARTICLE; CHEMOTAXIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ENDOTOXEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FLUORESCENCE ACTIVATED CELL SORTING; GRANULOCYTE; GROWTH REGULATED ONCOGENE ALPHA; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LEUKOCYTE ACTIVATION; MALE; NORMAL HUMAN; ONCOGENE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECEPTOR DOWN REGULATION;

CHEMOKINES, CXC; DOWN-REGULATION; ENDOTOXEMIA; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-8; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B;

EID: 1642376384     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOCI.0000018061.58504.75     Document Type: Article

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