메뉴 건너뛰기




Volumn 13, Issue 12, 2003, Pages 3757-3782

Mechanical interaction of heterogeneous cardiac muscle segments in silico: Effects on Ca2+ handling and action potential

Author keywords

Cardiac mechanoelectric feedback; Contractile function optimization; Dispersion of repolarization; Integrative mathematical modeling; Myocardium heterogeneity

Indexed keywords

CALCIUM; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; MATHEMATICAL MODELS; MUSCLE; OPTIMIZATION; POLARIZATION; POSITIVE IONS; TISSUE;

EID: 1642374487     PISSN: 02181274     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0218127403008983     Document Type: Article
Times cited : (45)

References (51)
  • 1
    • 0035194585 scopus 로고    scopus 로고
    • Electrical heterogeneity within the ventricular wall
    • Antzelevitch, C. & Fish, J. [2001] "Electrical heterogeneity within the ventricular wall," Basic Res. Cardiol. 96, 517-527.
    • (2001) Basic Res. Cardiol. , vol.96 , pp. 517-527
    • Antzelevitch, C.1    Fish, J.2
  • 2
    • 0035106613 scopus 로고    scopus 로고
    • Heterogeneous changes of monophasic action potential induced by sustained stretch in atrium
    • Babuty, D. & Lab, M. [2001] "Heterogeneous changes of monophasic action potential induced by sustained stretch in atrium," J. Cardiovasc. Electrophysiol. 12, 323-329.
    • (2001) J. Cardiovasc. Electrophysiol. , vol.12 , pp. 323-329
    • Babuty, D.1    Lab, M.2
  • 3
    • 0034683082 scopus 로고    scopus 로고
    • Calcium fluxes involved in control of cardiac myocyte contraction
    • Bers, D. M. [2000] "Calcium fluxes involved in control of cardiac myocyte contraction," Circ. Res. 87, 275-281.
    • (2000) Circ. Res. , vol.87 , pp. 275-281
    • Bers, D.M.1
  • 4
    • 0037049977 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling
    • Bers, D. M. [2002] "Cardiac excitation-contraction coupling," Nature 415, 198-205.
    • (2002) Nature , vol.415 , pp. 198-205
    • Bers, D.M.1
  • 5
    • 0030800885 scopus 로고    scopus 로고
    • Regional differences in electrical and mechanical properties of myocytes from guinea-pig hearts with mild left ventricular hypertrophy
    • Bryant, S. M., Shipsey, S. J. & Hart, G. [1997] "Regional differences in electrical and mechanical properties of myocytes from guinea-pig hearts with mild left ventricular hypertrophy," Cardiovasc. Res. 35, 315-323.
    • (1997) Cardiovasc. Res. , vol.35 , pp. 315-323
    • Bryant, S.M.1    Shipsey, S.J.2    Hart, G.3
  • 6
    • 0032944254 scopus 로고    scopus 로고
    • The role of calcium in the response of cardiac muscle to stretch
    • Calaghan, S. G. & White, E. [1999] "The role of calcium in the response of cardiac muscle to stretch," Prog. Biophys. Mol. Biol. 71, 59-90.
    • (1999) Prog. Biophys. Mol. Biol. , vol.71 , pp. 59-90
    • Calaghan, S.G.1    White, E.2
  • 7
    • 0033837012 scopus 로고    scopus 로고
    • Length-tension relationships of sub-epicardial and sub-endocardial single ventricular myocytes from rat and ferret hearts
    • Cazorla, O., Le Guennec, J. Y. & White, E. [2000] "Length-tension relationships of sub-epicardial and sub-endocardial single ventricular myocytes from rat and ferret hearts," J. Mol. Cell Cardiol. 32, 735-744.
    • (2000) J. Mol. Cell Cardiol. , vol.32 , pp. 735-744
    • Cazorla, O.1    Le Guennec, J.Y.2    White, E.3
  • 8
    • 0032999081 scopus 로고    scopus 로고
    • Heterogeneous distribution of the two components of delayed rectifier K+ current: A potential mechanism of the proarrhythmic effects of methanesulfonanilideclass III agents
    • Cheng, J., Kamiya, K., Liu, W., Tsuji, Y., Toyama, J. & Kodama, I. [1999] "Heterogeneous distribution of the two components of delayed rectifier K+ current: A potential mechanism of the proarrhythmic effects of methanesulfonanilideclass III agents," Cardiovasc. Res. 43, 135-147.
    • (1999) Cardiovasc. Res. , vol.43 , pp. 135-147
    • Cheng, J.1    Kamiya, K.2    Liu, W.3    Tsuji, Y.4    Toyama, J.5    Kodama, I.6
  • 9
    • 0034927316 scopus 로고    scopus 로고
    • Load-induced changes in repolarization: Evidence from experimental and clinical data
    • Eckardt, L., Kirchhof, P., Breithardt, G. & Haverkamp, W. [2001] "Load-induced changes in repolarization: Evidence from experimental and clinical data," Basic Res. Cardiol. 96, 369-380.
    • (2001) Basic Res. Cardiol. , vol.96 , pp. 369-380
    • Eckardt, L.1    Kirchhof, P.2    Breithardt, G.3    Haverkamp, W.4
  • 10
    • 0026794344 scopus 로고
    • Electrophysiological effects of myocardial stretch and mechanical determinants of stretchactivated arrhythmias
    • Franz, M. R., Cima, R., Wang, D., Profitt, D. & Kurz, R. [1992] "Electrophysiological effects of myocardial stretch and mechanical determinants of stretchactivated arrhythmias," Circul. 86, 968-978.
    • (1992) Circul. , vol.86 , pp. 968-978
    • Franz, M.R.1    Cima, R.2    Wang, D.3    Profitt, D.4    Kurz, R.5
  • 11
    • 0030183695 scopus 로고    scopus 로고
    • Mechano-electrical feedback in ventricular myocardium
    • Franz, M. R. [1996] "Mechano-electrical feedback in ventricular myocardium," Cardiovasc. Res. 32, 15-24.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 15-24
    • Franz, M.R.1
  • 12
    • 0033983563 scopus 로고    scopus 로고
    • Mechano-electrical feedback
    • Franz, M. R. [2000] "Mechano-electrical feedback," Cardiovasc. Res. 45, 263-266.
    • (2000) Cardiovasc. Res. , vol.45 , pp. 263-266
    • Franz, M.R.1
  • 13
    • 0030200991 scopus 로고    scopus 로고
    • A possible mechanism for large stretch-induced increase in [Ca2+]i in isolated guinea-pig ventricular myocytes
    • Gannier, F., White, E., Garnier & Le Guennec, J. Y. [1996] "A possible mechanism for large stretch-induced increase in [Ca2+]i in isolated guinea-pig ventricular myocytes," Cardiovasc. Res. 32, 158-167.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 158-167
    • Gannier, F.1    White, E.2    Garnier3    Le Guennec, J.Y.4
  • 15
    • 0036195894 scopus 로고    scopus 로고
    • Role of the Na(+)-Ca(2+) exchanger as an alternative trigger of CICR in mammalian cardiac myocytes
    • Han, C., Tavi, P. & Weckstrom, M. [2002] "Role of the Na(+)-Ca(2+) exchanger as an alternative trigger of CICR in mammalian cardiac myocytes," Biophys. J. 82, 1483-1496.
    • (2002) Biophys. J. , vol.82 , pp. 1483-1496
    • Han, C.1    Tavi, P.2    Weckstrom, M.3
  • 16
    • 0027532503 scopus 로고
    • Mechanoelectrical feedback effects of altering preload, afterload, and ventricular shortening
    • Hansen, D. E. [1993] "Mechanoelectrical feedback effects of altering preload, afterload, and ventricular shortening," Am. J. Physiol. 264, H423-H432.
    • (1993) Am. J. Physiol. , vol.264
    • Hansen, D.E.1
  • 17
    • 0029670185 scopus 로고    scopus 로고
    • Changes in [Ca2+]i, [Na+]i and Ca2+ current in isolated rat ventricular myocytes following an increase in cell length
    • Hongo, K., White, E., Le Guennec, J. Y. & Orchard, C. H. [1996] "Changes in [Ca2+]i, [Na+]i and Ca2+ current in isolated rat ventricular myocytes following an increase in cell length," J. Physiol. 491, 609-619.
    • (1996) J. Physiol. , vol.491 , pp. 609-619
    • Hongo, K.1    White, E.2    Le Guennec, J.Y.3    Orchard, C.H.4
  • 18
    • 0024517957 scopus 로고
    • Regulation of steady state filling in sarcoplasmic reticulum. Roles of back-inhibition, leakage, and slippage of the calcium pump
    • Inesi, G. & de Meis, L. [1989] "Regulation of steady state filling in sarcoplasmic reticulum. Roles of back-inhibition, leakage, and slippage of the calcium pump," J. Biol. Chem. 264, 5929-5936.
    • (1989) J. Biol. Chem. , vol.264 , pp. 5929-5936
    • Inesi, G.1    De Meis, L.2
  • 19
    • 0025987770 scopus 로고
    • Cooperative effects due to calcium binding by troponin and their consequences for contraction and relaxation of cardiac muscle under various conditions of mechanical loading
    • Izakov, V., Katsnelson, L. B., Blyakhman, F. A., Markhasin, V. S. & Shklyar, T. F. [1991] "Cooperative effects due to calcium binding by troponin and their consequences for contraction and relaxation of cardiac muscle under various conditions of mechanical loading," Circ. Res. 69, 1171-1184.
    • (1991) Circ. Res. , vol.69 , pp. 1171-1184
    • Izakov, V.1    Katsnelson, L.B.2    Blyakhman, F.A.3    Markhasin, V.S.4    Shklyar, T.F.5
  • 20
    • 0028855563 scopus 로고
    • Force, not sarcomere length, correlates with prolongation of isosarcometric contraction
    • Janssen, P. M. & Hunter, W. C. [1995] "Force, not sarcomere length, correlates with prolongation of isosarcometric contraction," Am. J. Physiol. 269, H676-H685.
    • (1995) Am. J. Physiol. , vol.269
    • Janssen, P.M.1    Hunter, W.C.2
  • 21
    • 0029933559 scopus 로고    scopus 로고
    • Mathematical modeling of relations between the kinetics of free intracellular calcium and mechanical function of myocardium
    • Katsnelson, L. B. & Markhasin, V. S. [1996] "Mathematical modeling of relations between the kinetics of free intracellular calcium and mechanical function of myocardium," J. Mol. Cell Cardiol. 28, 475-486.
    • (1996) J. Mol. Cell Cardiol. , vol.28 , pp. 475-486
    • Katsnelson, L.B.1    Markhasin, V.S.2
  • 22
    • 0034208549 scopus 로고    scopus 로고
    • Mathematical modeling of the effect of the sarcoplasmic reticulum calcium pump function on load dependent myocardial relaxation
    • Katsnelson, L. B., Markhasin, V. S. & Khazieva, N. S. [2000] "Mathematical modeling of the effect of the sarcoplasmic reticulum calcium pump function on load dependent myocardial relaxation," Gen. Physiol. Biophys. 19, 137-170.
    • (2000) Gen. Physiol. Biophys. , vol.19 , pp. 137-170
    • Katsnelson, L.B.1    Markhasin, V.S.2    Khazieva, N.S.3
  • 24
    • 0014987355 scopus 로고
    • Feedback interaction of mechanical and electrical events in the isolated mammalian ventricular myocardium (cat papillary muscle)
    • Kaufmann, R. L., Lab, M. J., Hennekes, R. & Krause, H. [1971] "Feedback interaction of mechanical and electrical events in the isolated mammalian ventricular myocardium (cat papillary muscle)," Pflugers. Arch. 324, 100-123.
    • (1971) Pflugers. Arch. , vol.324 , pp. 100-123
    • Kaufmann, R.L.1    Lab, M.J.2    Hennekes, R.3    Krause, H.4
  • 25
    • 0032893947 scopus 로고    scopus 로고
    • Stretch-induced changes in heart rate and rhythm: Clinical observations, experiments and mathematical models
    • Kohl, P., Hunter, P. & Noble, D. [1999] "Stretch-induced changes in heart rate and rhythm: Clinical observations, experiments and mathematical models," Prog. Biophys. Mol. Biol. 71, 91-138.
    • (1999) Prog. Biophys. Mol. Biol. , vol.71 , pp. 91-138
    • Kohl, P.1    Hunter, P.2    Noble, D.3
  • 26
    • 2042541227 scopus 로고    scopus 로고
    • Mechano-electric feedback in cardiac cells
    • Kohl, P. & Sachs, F. [2001] "Mechano-electric feedback in cardiac cells," Phil. Trans. R. Soc. Lond. A359, 1173-1185.
    • (2001) Phil. Trans. R. Soc. Lond. , vol.A359 , pp. 1173-1185
    • Kohl, P.1    Sachs, F.2
  • 27
    • 85047677311 scopus 로고
    • Transient depolarisation and action potential alterations following mechanical changes in isolated myocardium
    • Lab, M. J. [1980] "Transient depolarisation and action potential alterations following mechanical changes in isolated myocardium," Cardiovasc. Res. 14, 624-367.
    • (1980) Cardiovasc. Res. , vol.14 , pp. 624-367
    • Lab, M.J.1
  • 28
    • 0021686007 scopus 로고
    • The effects of shortening on myoplasmic calcium concentration and on the action potential in mammalian ventricular muscle
    • Lab, M. J., Allen, D. G. & Orchard, C. H. [1984] "The effects of shortening on myoplasmic calcium concentration and on the action potential in mammalian ventricular muscle," Circ. Res. 55, 825-829.
    • (1984) Circ. Res. , vol.55 , pp. 825-829
    • Lab, M.J.1    Allen, D.G.2    Orchard, C.H.3
  • 29
    • 0032926624 scopus 로고    scopus 로고
    • Mechanosensitivity as an integrative system in heart: An audit
    • Lab, M. J. [1999] "Mechanosensitivity as an integrative system in heart: An audit," Prog. Biophys. Mol. Biol. 71, 7-27.
    • (1999) Prog. Biophys. Mol. Biol. , vol.71 , pp. 7-27
    • Lab, M.J.1
  • 30
    • 0027367442 scopus 로고
    • Calcium channel currents recorded from isolated myocytes of rat basilar artery are stretch sensitive
    • Langton, P. D. [1993] "Calcium channel currents recorded from isolated myocytes of rat basilar artery are stretch sensitive," J. Physiol. 471, 1-11.
    • (1993) J. Physiol. , vol.471 , pp. 1-11
    • Langton, P.D.1
  • 32
    • 0003041054 scopus 로고
    • Functional consequences of regional heterogeneity in the left ventricle
    • eds. Glass, L., Hunter, P. & McCulloch, A. (Springer-Verlag, NY)
    • Lew, W. [1991] "Functional consequences of regional heterogeneity in the left ventricle," Theory of Heart: Biomechanics, Biophysics, and Nonlinear Dynamics of Cardiac Function, eds. Glass, L., Hunter, P. & McCulloch, A. (Springer-Verlag, NY), pp. H209-H237
    • (1991) Theory of Heart: Biomechanics, Biophysics, and Nonlinear Dynamics of Cardiac Function
    • Lew, W.1
  • 33
    • 0031151111 scopus 로고    scopus 로고
    • Mathematical modeling of the contribution of mechanical inhomogeneity in the myocardium to contractile function
    • Markhasin, V. S., Katsnelson, L. B., Nikitina, L. V. & Protsenko, Y. L. [1997] "Mathematical modeling of the contribution of mechanical inhomogeneity in the myocardium to contractile function," Gen. Physiol. Biophys. 16, 101-137.
    • (1997) Gen. Physiol. Biophys. , vol.16 , pp. 101-137
    • Markhasin, V.S.1    Katsnelson, L.B.2    Nikitina, L.V.3    Protsenko, Y.L.4
  • 35
    • 0038215383 scopus 로고    scopus 로고
    • Mechano-electric interactions in heterogeneous myocardium: Development of fundamental experimental and theoretical models
    • Markhasin, V. S., Solovyova, O., Katsnelson, L. B., Protsenko, Y., Kohl, P. & Noble, D. [2003] "Mechano-electric interactions in heterogeneous myocardium: Development of fundamental experimental and theoretical models," Prog. Biophys. Mol. Biol. 82, 207-220.
    • (2003) Prog. Biophys. Mol. Biol. , vol.82 , pp. 207-220
    • Markhasin, V.S.1    Solovyova, O.2    Katsnelson, L.B.3    Protsenko, Y.4    Kohl, P.5    Noble, D.6
  • 36
    • 0037098735 scopus 로고    scopus 로고
    • Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes
    • Natali, A. J., Wilson, L. A., Peckham, M., Turner, D. L., Harrison, S. M. & White, E. [2002] "Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes," J. Physiol. 541, 863-875.
    • (2002) J. Physiol. , vol.541 , pp. 863-875
    • Natali, A.J.1    Wilson, L.A.2    Peckham, M.3    Turner, D.L.4    Harrison, S.M.5    White, E.6
  • 37
    • 0030185302 scopus 로고    scopus 로고
    • Mechanoelectric feedback and atrial arrhythmias
    • Nazir, S. A. & Lab, M. J. [1996a] "Mechanoelectric feedback and atrial arrhythmias," Cardiovasc. Res. 32, 52-61.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 52-61
    • Nazir, S.A.1    Lab, M.J.2
  • 38
    • 0030184534 scopus 로고    scopus 로고
    • Mechanoelectric feedback in the atrium of the isolated guinea-pig heart
    • Nazir, S. A. & Lab, M. J. [1996b] "Mechanoelectric feedback in the atrium of the isolated guinea-pig heart," Cardiovasc. Res. 32, 112-119.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 112-119
    • Nazir, S.A.1    Lab, M.J.2
  • 40
    • 0031917543 scopus 로고    scopus 로고
    • Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes
    • Noble, D., Varghese, A., Kohl, P. & Noble, P. [1998] "Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes," Can. J. Cardiol. 14, 123-134.
    • (1998) Can. J. Cardiol. , vol.14 , pp. 123-134
    • Noble, D.1    Varghese, A.2    Kohl, P.3    Noble, P.4
  • 41
    • 0027535485 scopus 로고
    • Stretch-activated ion channels in tissue-cultured chick heart
    • Ruknudin, A., Sachs, F. & Bustamante, J. O. [1993] "Stretch-activated ion channels in tissue-cultured chick heart," Am. J. Physiol. 264, H960-H972.
    • (1993) Am. J. Physiol. , vol.264
    • Ruknudin, A.1    Sachs, F.2    Bustamante, J.O.3
  • 42
    • 0031792910 scopus 로고    scopus 로고
    • A critical role for L-type Ca2+ current in the regulation of Ca2+ release from the sarcoplasmic reticulum in human ventricular myocytes from dilated cardiomyopathy
    • Sipido, K. R., Stankovicova, T., Vanhaecke, J., Flameng, W. & Verdonck, F. [1998] "A critical role for L-type Ca2+ current in the regulation of Ca2+ release from the sarcoplasmic reticulum in human ventricular myocytes from dilated cardiomyopathy," Ann. N. Y. Acad. Sci. 853, 353-356.
    • (1998) Ann. N. Y. Acad. Sci. , vol.853 , pp. 353-356
    • Sipido, K.R.1    Stankovicova, T.2    Vanhaecke, J.3    Flameng, W.4    Verdonck, F.5
  • 43
  • 44
    • 0000870503 scopus 로고
    • The effect of coronary occlusion on myocardial contraction
    • Tanant, L. & Wiggers, C. [1935] "The effect of coronary occlusion on myocardial contraction," Am. J. Physiol. 112, 351-361.
    • (1935) Am. J. Physiol. , vol.112 , pp. 351-361
    • Tanant, L.1    Wiggers, C.2
  • 45
    • 0032583085 scopus 로고    scopus 로고
    • Mechanisms of stretch-induced changes in [Ca2+]i in rat atrial myocytes: Role of increased troponin C affinity and stretch-activated ion channels
    • Tavi, P., Han, C. & Weckstrom, M. [1998] "Mechanisms of stretch-induced changes in [Ca2+]i in rat atrial myocytes: Role of increased troponin C affinity and stretch-activated ion channels," Circ. Res. 83, 1165-1177.
    • (1998) Circ. Res. , vol.83 , pp. 1165-1177
    • Tavi, P.1    Han, C.2    Weckstrom, M.3
  • 46
    • 0027350688 scopus 로고
    • The effects of increasing cell length on auxotonic contractions; membrane potential and intracellular calcium transients in single guinea-pig ventricular myocytes
    • White, E., Le Guennec, J. Y., Nigretto, J. M., Gannier, F., Argibay, J. A. & Gamier, D. [1993] "The effects of increasing cell length on auxotonic contractions; membrane potential and intracellular calcium transients in single guinea-pig ventricular myocytes," Exp. Physiol. 78, 65-78.
    • (1993) Exp. Physiol. , vol.78 , pp. 65-78
    • White, E.1    Le Guennec, J.Y.2    Nigretto, J.M.3    Gannier, F.4    Argibay, J.A.5    Gamier, D.6
  • 47
    • 0001865380 scopus 로고
    • Interpretation of the intraventricular pressure curve on the basis of rapidly summated fractionate contractions
    • Wiggers, C. J. [1925] "Interpretation of the intraventricular pressure curve on the basis of rapidly summated fractionate contractions," Am. J. Physiol. 80, p. 1.
    • (1925) Am. J. Physiol. , vol.80 , pp. 1
    • Wiggers, C.J.1
  • 48
    • 0032879098 scopus 로고    scopus 로고
    • Functional, structural, and dynamic basis of electrical heterogeneity in healthy and diseased cardiac muscle: Implications for arrhythmogenesis and anti-arrhythmic drug therapy
    • Wolk, R., Cobbe, S. M., Hicks, M. N. & Kane, K. A. [1999] "Functional, structural, and dynamic basis of electrical heterogeneity in healthy and diseased cardiac muscle: Implications for arrhythmogenesis and anti-arrhythmic drug therapy," Pharmacol. Ther. 84, 207-231.
    • (1999) Pharmacol. Ther. , vol.84 , pp. 207-231
    • Wolk, R.1    Cobbe, S.M.2    Hicks, M.N.3    Kane, K.A.4
  • 49
    • 0032921368 scopus 로고    scopus 로고
    • Mapping propagation of mechanical activation in the paced heart with MRI tagging
    • Wyman, B. T., Hunter, W. C., Prinzen, F. W. & McVeigh, E. R. [1999] "Mapping propagation of mechanical activation in the paced heart with MRI tagging," Am. J. Physiol. 276, H881-H891.
    • (1999) Am. J. Physiol. , vol.276
    • Wyman, B.T.1    Hunter, W.C.2    Prinzen, F.W.3    McVeigh, E.R.4
  • 50
    • 0030200839 scopus 로고    scopus 로고
    • Stretch-induced voltage changes in the isolated beating heart: Importance of the timing of stretch and implications for stretch-activated ion channels
    • Zabel, M., Koller, B. S., Sachs, F. & Franz, M. R. [1996] "Stretch-induced voltage changes in the isolated beating heart: Importance of the timing of stretch and implications for stretch-activated ion channels," Cardiovasc. Res. 32, 120-130.
    • (1996) Cardiovasc. Res. , vol.32 , pp. 120-130
    • Zabel, M.1    Koller, B.S.2    Sachs, F.3    Franz, M.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.