Regional differences in electrical and mechanical properties of myocytes from guinea-pig hearts with mild left ventricular hypertrophy

Cardiovascular Research

Volumn 35, Issue 2, 1997, Pages 315-323

  Bryant, Simon M ^a   Shipsey, S Jane ^a   Hart, George ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Action potential duration; Calcium current; Guinea pig; Hypertrophy; Ventricular myocytes

Indexed keywords

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; FEMALE; GUINEA PIG; HEART ELECTROPHYSIOLOGY; HEART LEFT VENTRICLE HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; RAT; REENTRY ARRHYTHMIA; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS; CELL MEMBRANE; CELL SIZE; ELECTRIC CONDUCTIVITY; ENDOCARDIUM; FEMALE; GUINEA PIGS; HEART; HYPERTROPHY, LEFT VENTRICULAR; PATCH-CLAMP TECHNIQUES; PERICARDIUM;

EID: 0030800885     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00111-9     Document Type: Article

References (31)

1. Litovsky SH, Antzelevitch C. Transient outward current prominent in canine ventricular epicardium but not endocardium. Circ Res 1988;62:116-126.
2. Liu D-W, Gintant GA, Antzelevitch C. Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle. Circ Res 1993;72:671-687.
3. Furukawa T, Myerburg RJ, Furukawa N, Bassett AL, Kimura S. Differences in transient outward currents of feline endocardial and epicardial myocytes. Circ Res 1990;67:1287-1291.
4. Fedida D, Giles WR. Regional variations in action potentials and transient outward current in myocytes isolated from rabbit left ventricle. J Physiol Lond 1991;442:191-209.
5. Wettwer E, Amos GJ, Posival H, Ravens U. Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin. Circ Res 1994;75:473-482.
6. Näbauer M, Beuckelmann DJ, Überfuhr P, Steinbeck G. Regional defferences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle. Circulation 1996;93:168-177.
7. Shipsey SJ, Ryder, KO, Bryant SM, Hart G. Regional action potential changes in isolated ventricular myocytes from rats with catecholamine-induced cardiac hypertrophy. J Physiol Lond 1995;489:142P.
8. Clark RB, Bouchard RA, Salinas-Stefanon E, Sanchez-Chapula J, Giles WR. Heterogeneity of action potential waveforms and potassium currents in rat ventricle. Cardiovasc Res 1993;27:1795-1799.
9. Hirano Y, Hiraoka M. Barium-induced automatic activity in isolated ventricular myocytes from guinea-pig hearts. J Physiol Lond 1988;395:455-472.
10. Ryder KO, Bryant SM, Hart G. Membrane current changes in left ventricular myocytes isolated from guinea pigs after abdominal aortic coarctation. Cardiovasc Res 1993;27:1278-1287.
11. Watanabe T, Rautaharju PM, McDonald TF. Ventricular action potentials, ventricular extracellular potentials, and the ECG of guinea pig. Circ Res 1985;57:362-373.
12. Main MC, Bryant SM, Hart G. Electrical and mechanical characteristics of guinea-pig ventricular myocytes from apical epicardium and basal endocardium. J Physiol Lond 1995;483:8P.
13. Furukawa T, Kimura S, Furukawa N, Bassett AL, Myerburg RJ. Potassium rectifier currents differ in myocytes of endocardial and epicardial origin. Circ Res 1992;70:91-103.
14. Antzelevitch C, Sicouri S, Litovsky SH, et al. Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells. Circ Res 1991;69:1427-1449.
15. Keung ECH, Aronson RS. Non-uniform electrophysiological properties and electrotonic interaction in hypertrophied rat myocardium. Circ Res 1981;49:150-158.
16. Bénitah J-P, Gomez AM, Bailly P, et al. Heterogeneity of the early outward current in ventricular cells isolated from normal and hypertrophied rat hearts. J Physiol Lond 1993;469:111-138.
17. Boyett MR, Moore M, Jewell BR, Montgomery RAP, Kirby MS, Orchard CH. An improved apparatus for the optical recording of contraction in single heart cells. Pflüger's Arch 1988;413:197-205.
18. Egan TM, Noble D, Noble SJ, Powell T, Spindler AJ, Twist VW. Sodium-calcium exchange during the action potential in guinea-pig ventricular cells. J Physiol Lond 1989;411:639-662.
19. Hart G. Cellular electrophysiology in cardiac hypertrophy and failure. Cardiovasc Res 1994;28:933-946.
20. Coraboeuf E, Nargeot J. Electrophysiology of human cardiac cells. Cardiovasc Res 1993;27:1713-1725.
21. Main MC, Bryant SM, Hart G. Delayed rectifier current density is greater in guinea-pig left ventricular epicardial myocytes than endocardial myocytes. J Mol Cell Cardiol 1996;28:P18.
22. 2+ exchanger in end-stage human heart failure. Circ Res 1994;75:443-453.
23. Chamunorwa JP, O'Neill SC. Regional differences in rest decay and recoveries of contraction and calcium transient in rabbit ventricular muscle. Pflüger's Arch 1995;430:195-204.
24. Lecarpentier Y, Waldenström A, Clergue M, et al. Major alterations in relaxation during cardiac hypertrophy induced by aortic stenosis in guinea pig. Circ Res 1987;61:107-116.
25. Naqvi RU, MacLeod KT. Effect of hypertrophy on mechanisms of relaxation in isolated cardiac myocytes from guinea pig. Am J Physiol 1994;267:H1851-H1861.
26. Schouten VJA, Vliegen HW, van der Laarse A, Huysmans HA. Altered calcium handling at normal contractility in hypertrophied rat heart. J Mol Cell Cardiol 1990;22:987-998.
27. Siri FM, Krueger J, Nordin C, Ming Z, Aronson RS. Depressed intracellular calcium transients and contraction in myocytes from hypertrophied and failing guinea pig hearts. Am J Physiol 1991;261:H514-H530.
28. Noble D, Cohen I. The interpretation of the T wave of the electrocardiogram. Cardiovasc Res 1978;12:13-27.
29. Kanai A, Salama G. Optical mapping reveals that repolarisation spreads anisotopically and is guided by fiber orientation in guinea pig hearts. Circ Res 1995;77:784-802.
30. Efimov IR, Huang DT, Rendt JM, Salama G. Optical mapping of repolarisation and refractoriness from intact hearts. Circulation 1994;90:1469-1480.
31. Jalife J, Gray R. Drifting vortices of electrical waves underlie ventricular fibrillation in the rabbit heart. Acta Physiol Scand 1996;157:123-131.